Search Results - "CHARLES, Pierre Emmanuel"
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Combination biomarkers to diagnose sepsis in the critically ill patient
Published in American journal of respiratory and critical care medicine (01-07-2012)“…Although the outcome of sepsis benefits from the prompt administration of appropriate antibiotics on correct diagnosis, the assessment of infection in…”
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CXCL10 could drive longer duration of mechanical ventilation during COVID-19 ARDS
Published in Critical care (London, England) (02-11-2020)“…COVID-19-related ARDS has unique features when compared with ARDS from other origins, suggesting a distinctive inflammatory pathogenesis. Data regarding the…”
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The dysregulated innate immune response in severe COVID-19 pneumonia that could drive poorer outcome
Published in Journal of translational medicine (03-12-2020)“…Although immune modulation is a promising therapeutic avenue in coronavirus disease 2019 (COVID-19), the most relevant targets remain to be found. COVID-19 has…”
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Mitochondrial alarmins are tissue mediators of ventilator-induced lung injury and ARDS
Published in PloS one (22-11-2019)“…Endogenous tissue mediators inducing lung inflammation in the context of ventilator-induced lung injury (VILI) and acute respiratory distress syndrome (ARDS)…”
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Incidence and Predictors of New-Onset Atrial Fibrillation in Septic Shock Patients in a Medical ICU: Data from 7-Day Holter ECG Monitoring
Published in PloS one (12-05-2015)“…We investigated incidence, risk factors for new-onset atrial fibrillation (NAF), and prognostic impact during septic shock in medical Intensive Care Unit (ICU)…”
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Ten-year experience with arterial embolization for peptic ulcer bleeding: N-butyl cyanoacrylate glue versus other embolic agents
Published in European radiology (01-05-2021)“…Objectives To compare our experience with N-butyl cyanoacrylate glue as the primary embolic agent versus other embolic agents for transcatheter arterial…”
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Pneumococcal pneumonia and endotoxemia: An experimental and clinical reappraisal
Published in European journal of clinical investigation (01-01-2024)“…Background Circulating endotoxins could result from bacterial digestive translocation during sepsis, thus contributing to uncontrolled systemic inflammation,…”
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Are adipokines the missing link between obesity, immune response, and outcomes in severe COVID-19?
Published in International Journal of Obesity (01-09-2021)“…Introduction Obesity is commonly reported in COVID-19 patients and is associated with poorer outcomes. It is suggested that leptin could be the missing link…”
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Usefulness of the “Candida score” for discriminating between Candida colonization and invasive candidiasis in non-neutropenic critically ill patients: A prospective multicenter study
Published in Critical care medicine (01-05-2009)“…OBJECTIVE:To assess the usefulness of the “Candida score” (CS) for discriminating between Candida species colonization and invasive candidiasis (IC) in…”
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Role of the interstitium during septic shock: a key to the understanding of fluid dynamics?
Published in Journal of intensive care (10-10-2023)“…Background While not traditionally included in the conceptual understanding of circulation, the interstitium plays a critical role in maintaining fluid…”
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Linezolid and atorvastatin impact on pneumonia caused by Staphyloccocus aureus in rabbits with or without mechanical ventilation
Published in PloS one (17-11-2017)“…Pneumonia may involve methicillin-resistant Staphylococcus aureus (MRSA), with elevated rates of antibiotics failure. The present study aimed to assess the…”
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Biomarker-guided antifungal therapy in patients with suspected invasive candidiasis: Ready for prime time?
Published in Intensive care medicine (01-12-2017)Get full text
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Septic patients without obvious signs of infection at baseline are more likely to die in the ICU
Published in BMC infectious diseases (02-03-2022)“…Early identification of sepsis is mandatory. However, clinical presentation is sometimes misleading given the lack of infection signs. The objective of the…”
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Safety and efficacy of transcatheter embolization with Glubran®2 cyanoacrylate glue for acute arterial bleeding: a single-center experience with 104 patients
Published in Abdominal radiology (New York) (01-03-2018)“…Purpose To assess the efficacy and the safety of Glubran ® 2 n -butyl cyanoacrylate metacryloxysulfolane (NBCA-MS) transcatheter arterial embolization (TAE)…”
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High plasma concentration of non-esterified polyunsaturated fatty acids is a specific feature of severe COVID-19 pneumonia
Published in Scientific reports (24-05-2021)“…COVID-19 pneumonia has specific features and outcomes that suggests a unique immunopathogenesis. Severe forms of COVID-19 appear to be more frequent in obese…”
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Mechanical Ventilation Alters the Development of Staphylococcus aureus Pneumonia in Rabbit
Published in PloS one (08-07-2016)“…Ventilator-associated pneumonia (VAP) is common during mechanical ventilation (MV). Beside obvious deleterious effects on muco-ciliary clearance, MV could…”
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Empirical antifungal therapy with an echinocandin in critically-ill patients: prospective evaluation of a pragmatic Candida score-based strategy in one medical ICU
Published in BMC infectious diseases (11-07-2014)“…Invasive candidiasis (IC) is a life-threatening ICU-acquired infection. A strong correlation between time to antifungal therapy (AFT) administration and…”
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Which algorithm diagnoses invasive pulmonary aspergillosis best in ICU patients with COPD?
Published in The European respiratory journal (01-09-2017)“…Invasive pulmonary aspergillosis (IPA) is a potentially lethal opportunistic infection, mainly affecting immunocompromised patients, particularly those with…”
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Correction to: CXCL10 could drive longer duration of mechanical ventilation during COVID-19 ARDS
Published in Critical care (London, England) (13-04-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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Corporeal Compression at the Onset of Septic shock (COCOONs): a compression method to reduce fluid balance of septic shock patients
Published in Scientific reports (09-08-2019)“…Fluid overload in septic intensive care unit (ICU) patients is common and strongly associated with poor outcome. There is currently no treatment for capillary…”
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