Search Results - "CHAPONDA, M"

Failure of malaria control in Nchelenge District, Zambia by Chaponda, M, Mulenga, M

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Managing potential drug-drug interactions between gastric acid-reducing agents and antiretroviral therapy: experience from a large HIV-positive cohort by Lewis, J M, Stott, K E, Monnery, D, Seden, K, Beeching, N J, Chaponda, M, Khoo, S, Beadsworth, M B J

“…Drug-drug interactions between antiretroviral therapy and other drugs are well described. Gastric acid-reducing agents are one such class. However, few data…”
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PP122—Regulation of human leukocyte antigen expression and nevirapine-induced adverse drug reactions in a malawian hiv-positive population by Cornejo Castro, E.M, Carr, D.F, Marshall, V.A, Chaponda, M, Lane, S, Alfirevic, A, Whitby, D, Carrington, M, Pirmohamed, M

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Favourable one-year ART outcomes in adult Malawians with hepatitis B and C co-infection by Moore, E, Beadsworth, M.B.J, Chaponda, M, Mhango, B, Faragher, B, Njala, J, Hofland, H.W.C, Davies, J, Hart, I.J, Beeching, N.J, Zijlstra, E.E, van Oosterhout, J.J

“…Summary Background Few studies have investigated the impact of chronic hepatitis B and C infection on antiretroviral therapy (ART) outcomes in sub-Saharan…”
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Bacteraemia and mortality among adult medical admissions in Malawi: Predominance of non-typhi salmonellae and Streptococcus pneumoniae by GORDON, M. A, WALSH, A. L, CHAPONDA, M, SOKO, D, MBVWINJI, M, MOLYNEUX, M. E, GORDON, S. B

“…The high seroprevalence of HIV in Malawi might be expected to alter the pattern of pathogens isolated from bacteraemic patients. We aimed to describe the…”
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A rapid and sensitive HPLC–MS method for the detection of plasma and cellular rifampicin by Hartkoorn, Ruben C., Khoo, Saye, Back, David J., Tjia, John F., Waitt, Catriona J., Chaponda, Masautso, Davies, Geraint, Ardrey, Alison, Ashleigh, Samantha, Ward, Stephen A.

“…Rifampicin is active against both intracellular and extracellular Mycobacterium tuberculosis. The ability to measure rifampicin drug concentrations in both…”
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Reliability of rapid testing for hepatitis B in a region of high HIV endemicity by Davies, J., van Oosterhout, J.J.G., Nyirenda, M., Bowden, J., Moore, E., Hart, I.J., Zijlstra, E.E., Chaponda, M., Faragher, B., Beeching, N.J., Beadsworth, M.B.J.

“…Hepatitis B (HBV) and HIV co-infection is common in resource-poor settings. A recent study from Malawi revealed poor correlation between hepatitis B surface…”
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Utility of therapeutic drug monitoring in the management of HIV-infected pregnant women in receipt of lopinavir by Caswell, R J, Phillips, D, Chaponda, M, Khoo, S H, Taylor, G P, Ghanem, M, Poulton, M, Welch, J, Gibbons, S, Jackson, V, Lambert, J S

“…The pharmacokinetics of antiretroviral drugs in pregnancy is poorly understood. We reviewed the use of therapeutic drug monitoring (TDM) in clinical settings…”
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The value of the post-take ward round: are new working patterns compromising junior doctor education? by Chaponda, M, Borra, M, Beeching, NJ, Almond, DS, Williams, PS, Hammond, MA, Price, VA, Tarry, L, Taegtmeyer, M

“…This prospective observational study assessed the impact of the changes in junior doctors' working hours and waiting-time initiatives on teaching and learning…”
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Cost-saving through microscopy-based versus presumptive diagnosis of malaria in adult outpatients in Malawi by JONKMAN, A, CHIBWE, R. A, KHOROMANA, C. O, LIABUNYA, U. L, CHAPONDA, M. E, KANDIERO, G. E, MOLYNEUX, M. E, TAYLOR, T. E

“…The cost implications of changing from a policy of presumptive diagnosis to one of microscopy-based diagnosis in the management of uncomplicated malaria in an…”
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Bacteraemia and Mortality Among Adult Medical Admissions in Malawi – Predominance of Non-typhi Salmonellae andStreptococcus pneumoniae by Gordon, M.A., Walsh, A.L., Chaponda, M., Soko, D., Mbvwinji, M., Molyneux, M.E., Gordon, S.B.

“…Objectives: The high seroprevalence of HIV in Malawi might be expected to alter the pattern of pathogens isolated from bacteraemic patients. We aimed to…”
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Monitoring of older HIV‐1‐positive adults by HIV clinics in the United Kingdom: a national quality improvement initiative by Ekong, N, Curtis, H, Ong, E, Sabin, CA, Chadwick, D, Asboe, D., Balasubramaniam, V., Burns, F., Chadwick, D., Chaponda, M., Churchill, D., Delpech, V., Ekong, N., Freedman, A., Kaide, E., Kulasegaram, R., Larbalestier, N., Lowndes, K., Mbewe, R., Olarinde, O., Ong, E., Pires, S., Sabin, C., Sullivan, A., Vera, J.

“…Objectives The aim of the study was to describe a UK‐wide process to assess adherence to guidelines for the routine investigation and monitoring of…”
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Hepatitis B Virus Sub-genotype A1 Infection Is Characterized by High Replication Levels and Rapid Emergence of Drug Resistance in HIV-Positive Adults Receiving First-line Antiretroviral Therapy in Malawi by Aoudjane, Samir, Chaponda, Mas, del Castillo, Antonio Adrián González, O'Connor, Jemma, Noguera, Marc, Beloukas, Apostolos, Hopkins, Mark, Khoo, Saye, van Oosterhout, Joep J., Geretti, Anna Maria

“…Background. It has been proposed that hepatitis B virus (HBV) sub-genotype A1 infections have mild outcomes and a low risk of drug-resistance among patients…”
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Characteristics of people brought in dead at the Ndola Teaching Hospital in Zambia between 2012 and 2016 by Hachizovu, S, Chaponda, M, Manyando, C, Mubikayi, D, Mulenga, M, Makupe, A

“…Background: Death is the end spectrum of everyone's life. From a policy maker's point of view, the cause of death and the place of death are important…”
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Characteristics of people brought in dead at the Ndola Teaching Hospital in Zambia between 2012 and 2016 by Hachizovu, S, Chaponda, M, Manyando, C, Mubikayi, D, Mulenga, M, Makupe, A

“…Background: Death is the end spectrum of everyone's life. From a policy maker's point of view, the cause of death and the place of death are important…”
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Psychological wellbeing and use of alcohol and recreational drugs: results of the British HIV Association (BHIVA) national audit 2017 by Parry, S, Curtis, H, Chadwick, D

“…Objectives The aim of this national audit was to assess adherence of services providing HIV care in the UK to national standards and guidelines regarding…”
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CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations by Carr, Daniel F, Chaponda, Mas, Cornejo Castro, Elena M, Jorgensen, Andrea L, Khoo, Saye, Van Oosterhout, Joep J, Dandara, Collet, Kampira, Elizabeth, Ssali, Francis, Munderi, Paula, Lalloo, David G, Heyderman, Robert S, Pirmohamed, Munir

“…Nevirapine, an NNRTI used in HIV treatment, can cause hypersensitivity reactions in 6%-10% of patients. In the most serious cases (1.3%) this can manifest as…”
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Self-harm in young people with perinatal HIV and HIV negative young people in England: cross sectional analysis by Copelyn, Julie, Thompson, Lindsay C, Le Prevost, Marthe, Castro, Hannah, Sturgeon, Kate, Rowson, Katie, Brice, Susie, Foster, Caroline, Gibb, Diana M, Judd, Ali

“…Self-harm in adolescents is of growing concern internationally but limited evidence exists on the prevalence of self-harm in those living with HIV, who may be…”
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Sociodemographic features and treatment outcomes of patients with HIV and hepatitis C co-infection: a descriptive study by Williams, J, Railton, E, Wingfield, T, Chaponda, M

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potential of cytokines as safety biomarkers for drug-induced liver injury by Laverty, Hugh G, Antoine, Daniel J, Benson, Craig, Chaponda, Masautso, Williams, Dominic, Park, B. Kevin

“…Drug-induced liver injury (DILI) is an event that has a detrimental impact on drug development and patient safety; therefore the identification of novel…”
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