Search Results - "CHAPMAN, Sinead B"

The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum by Neafsey, Daniel E, Galinsky, Kevin, Jiang, Rays H Y, Young, Lauren, Sykes, Sean M, Saif, Sakina, Gujja, Sharvari, Goldberg, Jonathan M, Young, Sarah, Zeng, Qiandong, Chapman, Sinéad B, Dash, Aditya P, Anvikar, Anupkumar R, Sutton, Patrick L, Birren, Bruce W, Escalante, Ananias A, Barnwell, John W, Carlton, Jane M

“…Jane Carlton and colleagues report the genome sequencing, de novo assembly and annotation of four Plasmodium vivax reference strains from diverse geographic…”
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Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal by Cohen, Keira A, Abeel, Thomas, Manson McGuire, Abigail, Desjardins, Christopher A, Munsamy, Vanisha, Shea, Terrance P, Walker, Bruce J, Bantubani, Nonkqubela, Almeida, Deepak V, Alvarado, Lucia, Chapman, Sinéad B, Mvelase, Nomonde R, Duffy, Eamon Y, Fitzgerald, Michael G, Govender, Pamla, Gujja, Sharvari, Hamilton, Susanna, Howarth, Clinton, Larimer, Jeffrey D, Maharaj, Kashmeel, Pearson, Matthew D, Priest, Margaret E, Zeng, Qiandong, Padayatchi, Nesri, Grosset, Jacques, Young, Sarah K, Wortman, Jennifer, Mlisana, Koleka P, O'Donnell, Max R, Birren, Bruce W, Bishai, William R, Pym, Alexander S, Earl, Ashlee M

“…The continued advance of antibiotic resistance threatens the treatment and control of many infectious diseases. This is exemplified by the largest global…”
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Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events by Lemieux, Jacob E, Siddle, Katherine J, Shaw, Bennett M, Loreth, Christine, Schaffner, Stephen F, Gladden-Young, Adrianne, Adams, Gordon, Fink, Timelia, Tomkins-Tinch, Christopher H, Krasilnikova, Lydia A, DeRuff, Katherine C, Rudy, Melissa, Bauer, Matthew R, Lagerborg, Kim A, Normandin, Erica, Chapman, Sinéad B, Reilly, Steven K, Anahtar, Melis N, Lin, Aaron E, Carter, Amber, Myhrvold, Cameron, Kemball, Molly E, Chaluvadi, Sushma, Cusick, Caroline, Flowers, Katelyn, Neumann, Anna, Cerrato, Felecia, Farhat, Maha, Slater, Damien, Harris, Jason B, Branda, John A, Hooper, David, Gaeta, Jessie M, Baggett, Travis P, O'Connell, James, Gnirke, Andreas, Lieberman, Tami D, Philippakis, Anthony, Burns, Meagan, Brown, Catherine M, Luban, Jeremy, Ryan, Edward T, Turbett, Sarah E, LaRocque, Regina C, Hanage, William P, Gallagher, Glen R, Madoff, Lawrence C, Smole, Sandra, Pierce, Virginia M, Rosenberg, Eric, Sabeti, Pardis C, Park, Daniel J, MacInnis, Bronwyn L

“…Analysis of 772 complete severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes from early in the Boston-area epidemic revealed numerous…”
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Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak by Gire, Stephen K., Goba, Augustine, Andersen, Kristian G., Sealfon, Rachel S. G., Park, Daniel J., Kanneh, Lansana, Jalloh, Simbirie, Momoh, Mambu, Fullah, Mohamed, Dudas, Gytis, Wohl, Shirlee, Moses, Lina M., Yozwiak, Nathan L., Winnicki, Sarah, Matranga, Christian B., Malboeuf, Christine M., Qu, James, Gladden, Adrianne D., Schaffner, Stephen F., Yang, Xiao, Jiang, Pan-Pan, Nekoui, Mahan, Colubri, Andres, Coomber, Moinya Ruth, Fonnie, Mbalu, Moigboi, Alex, Gbakie, Michael, Kamara, Fatima K., Tucker, Veronica, Konuwa, Edwin, Saffa, Sidiki, Sellu, Josephine, Jalloh, Abdul Azziz, Kovoma, Alice, Koninga, James, Mustapha, Ibrahim, Kargbo, Kandeh, Foday, Momoh, Yillah, Mohamed, Kanneh, Franklyn, Robert, Willie, Massally, James L. B., Chapman, Sinéad B., Bochicchio, James, Murphy, Cheryl, Nusbaum, Chad, Young, Sarah, Birren, Bruce W., Grant, Donald S., Scheiffelin, John S., Lander, Eric S., Happi, Christian, Gevao, Sahr M., Gnirke, Andreas, Rambaut, Andrew, Garry, Robert F., Khan, S. Humarr, Sabeti, Pardis C.

“…In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78…”
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Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks by Cerqueira, Gustavo C., Earl, Ashlee M., Ernst, Christoph M., Grad, Yonatan H., Dekker, John P., Feldgarden, Michael, Chapman, Sinéad B., Reis-Cunha, João L., Shea, Terrance P., Young, Sarah, Zeng, Qiandong, Delaney, Mary L., Kim, Diane, Peterson, Ellena M., O’Brien, Thomas F., Ferraro, Mary Jane, Hooper, David C., Huang, Susan S., Kirby, James E., Onderdonk, Andrew B., Birren, Bruce W., Hung, Deborah T., Cosimi, Lisa A., Wortman, Jennifer R., Murphy, Cheryl I., Hanage, William P.

“…Carbapenem-resistant Enterobacteriaceae (CRE) are among the most severe threats to the antibiotic era. Multiple different species can exhibit resistance due to…”
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Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance by Manson, Abigail L, Cohen, Keira A, Abeel, Thomas, Desjardins, Christopher A, Armstrong, Derek T, Barry, Clifton E, Brand, Jeannette, Chapman, Sinéad B, Cho, Sang-Nae, Gabrielian, Andrei, Gomez, James, Jodals, Andreea M, Joloba, Moses, Jureen, Pontus, Lee, Jong Seok, Malinga, Lesibana, Maiga, Mamoudou, Nordenberg, Dale, Noroc, Ecaterina, Romancenco, Elena, Salazar, Alex, Ssengooba, Willy, Velayati, A A, Winglee, Kathryn, Zalutskaya, Aksana, Via, Laura E, Cassell, Gail H, Dorman, Susan E, Ellner, Jerrold, Farnia, Parissa, Galagan, James E, Rosenthal, Alex, Crudu, Valeriu, Homorodean, Daniela, Hsueh, Po-Ren, Narayanan, Sujatha, Pym, Alexander S, Skrahina, Alena, Swaminathan, Soumya, Van der Walt, Martie, Alland, David, Bishai, William R, Cohen, Ted, Hoffner, Sven, Birren, Bruce W, Earl, Ashlee M

“…Ashlee Earl and colleagues analyze whole-genome sequences from 5,310 Mycobacterium tuberculosis isolates from five continents. They find that resistance to…”
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Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia by Palmer, Duncan S., Howrigan, Daniel P., Chapman, Sinéad B., Adolfsson, Rolf, Bass, Nick, Blackwood, Douglas, Boks, Marco P. M., Chen, Chia-Yen, Churchhouse, Claire, Corvin, Aiden P., Craddock, Nicholas, Curtis, David, Di Florio, Arianna, Dickerson, Faith, Freimer, Nelson B., Goes, Fernando S., Jia, Xiaoming, Jones, Ian, Jones, Lisa, Jonsson, Lina, Kahn, Rene S., Landén, Mikael, Locke, Adam E., McIntosh, Andrew M., McQuillin, Andrew, Morris, Derek W., O’Donovan, Michael C., Ophoff, Roel A., Owen, Michael J., Pedersen, Nancy L., Posthuma, Danielle, Reif, Andreas, Risch, Neil, Schaefer, Catherine, Scott, Laura, Singh, Tarjinder, Smoller, Jordan W., Solomonson, Matthew, Clair, David St, Stahl, Eli A., Vreeker, Annabel, Walters, James T. R., Wang, Weiqing, Watts, Nicholas A., Yolken, Robert, Zandi, Peter P., Neale, Benjamin M.

“…We report results from the Bipolar Exome (BipEx) collaboration analysis of whole-exome sequencing of 13,933 patients with bipolar disorder (BD) matched with…”
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Increasing diversity in genomics requires investment in equitable partnerships and capacity building by Martin, Alicia R., Stroud, Rocky E., Abebe, Tamrat, Akena, Dickens, Alemayehu, Melkam, Atwoli, Lukoye, Chapman, Sinéad B., Flowers, Katelyn, Gelaye, Bizu, Gichuru, Stella, Kariuki, Symon M., Kinyanjui, Sam, Korte, Kristina J., Koen, Nastassja, Koenen, Karestan C., Newton, Charles R. J. C., Olivares, Ana Maria, Pollock, Sam, Post, Kristianna, Singh, Ilina, Stein, Dan J., Teferra, Solomon, Zingela, Zukiswa, Chibnik, Lori B.

“…Calls for diversity in genomics have motivated new global research collaborations across institutions with highly imbalanced resources. We describe practical…”
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Low-coverage sequencing cost-effectively detects known and novel variation in underrepresented populations by Martin, Alicia R., Atkinson, Elizabeth G., Chapman, Sinéad B., Stevenson, Anne, Stroud, Rocky E., Abebe, Tamrat, Akena, Dickens, Alemayehu, Melkam, Ashaba, Fred K., Atwoli, Lukoye, Bowers, Tera, Chibnik, Lori B., Daly, Mark J., DeSmet, Timothy, Dodge, Sheila, Fekadu, Abebaw, Ferriera, Steven, Gelaye, Bizu, Gichuru, Stella, Injera, Wilfred E., James, Roxanne, Kariuki, Symon M., Kigen, Gabriel, Koenen, Karestan C., Kwobah, Edith, Kyebuzibwa, Joseph, Majara, Lerato, Musinguzi, Henry, Mwema, Rehema M., Neale, Benjamin M., Newman, Carter P., Newton, Charles R.J.C., Pickrell, Joseph K., Ramesar, Raj, Shiferaw, Welelta, Stein, Dan J., Teferra, Solomon, van der Merwe, Celia, Zingela, Zukiswa

“…Genetic studies in underrepresented populations identify disproportionate numbers of novel associations. However, most genetic studies use genotyping arrays…”
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Extensive global movement of multidrug-resistant M. tuberculosis strains revealed by whole-genome analysis by Cohen, Keira A, Manson, Abigail L, Abeel, Thomas, Desjardins, Christopher A, Chapman, Sinead B, Hoffner, Sven, Birren, Bruce W, Earl, Ashlee M

“…While the international spread of multidrug-resistant (MDR) strains is an acknowledged public health threat, a broad and more comprehensive examination of the…”
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Phylogenomic Classification and the Evolution of Clonal Complex 5 Methicillin-Resistant Staphylococcus aureus in the Western Hemisphere by Challagundla, Lavanya, Reyes, Jinnethe, Rafiqullah, Iftekhar, Sordelli, Daniel O, Echaniz-Aviles, Gabriela, Velazquez-Meza, Maria E, Castillo-Ramírez, Santiago, Fittipaldi, Nahuel, Feldgarden, Michael, Chapman, Sinéad B, Calderwood, Michael S, Carvajal, Lina P, Rincon, Sandra, Hanson, Blake, Planet, Paul J, Arias, Cesar A, Diaz, Lorena, Robinson, D Ashley

“…Clonal complex 5 methicillin-resistant (CC5-MRSA) includes multiple prevalent clones that cause hospital-associated infections in the Western Hemisphere. Here,…”
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Sequencing of Culex quinquefasciatus Establishes a Platform for Mosquito Comparative Genomics by Arensburger, Peter, Megy, Karine, Waterhouse, Robert M, Abrudan, Jenica, Amedeo, Paolo, Antelo, Beatriz, Bartholomay, Lyric, Bidwell, Shelby, Caler, Elisabet, Camara, Francisco, Campbell, Corey L, Campbell, Kathryn S, Casola, Claudio, Castro, Marta T, Chandramouliswaran, Ishwar, Chapman, Sinéad B, Christley, Scott, Costas, Javier, Eisenstadt, Eric, Feschotte, Cedric, Fraser-Liggett, Claire, Guigo, Roderic, Haas, Brian, Hammond, Martin, Hansson, Bill S, Hemingway, Janet, Hill, Sharon R, Howarth, Clint, Ignell, Rickard, Kennedy, Ryan C, Kodira, Chinnappa D, Lobo, Neil F, Mao, Chunhong, Mayhew, George, Michel, Kristin, Mori, Akio, Liu, Nannan, Naveira, Horacio, Nene, Vishvanath, Nguyen, Nam, Pearson, Matthew D, Pritham, Ellen J, Puiu, Daniela, Qi, Yumin, Ranson, Hilary, Ribeiro, Jose M.C, Roberston, Hugh M, Severson, David W, Shumway, Martin, Stanke, Mario, Strausberg, Robert L, Sun, Cheng, Sutton, Granger, Tu, Zhijian (Jake), Tubio, Jose Manuel C, Unger, Maria F, Vanlandingham, Dana L, Vilella, Albert J, White, Owen, White, Jared R, Wondji, Charles S, Wortman, Jennifer, Zdobnov, Evgeny M, Birren, Bruce, Christensen, Bruce M, Collins, Frank H, Cornel, Anthony, Dimopoulos, George, Hannick, Linda I, Higgs, Stephen, Lanzaro, Gregory C, Lawson, Daniel, Lee, Norman H, Muskavitch, Marc A.T, Raikhel, Alexander S, Atkinson, Peter W

“…Culex quinquefasciatus (the southern house mosquito) is an important mosquito vector of viruses such as West Nile virus and St. Louis encephalitis virus, as…”
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Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections by Straub, Timothy J, Chou, Wen-Chi, Manson, Abigail L, Schreiber, 4th, Henry L, Walker, Bruce J, Desjardins, Christopher A, Chapman, Sinéad B, Kaspar, Kerrie L, Kahsai, Orsalem J, Traylor, Elizabeth, Dodson, Karen W, Hullar, Meredith A J, Hultgren, Scott J, Khoo, Christina, Earl, Ashlee M

“…Urinary tract infections (UTIs) affect 15 million women each year in the United States, with > 20% experiencing frequent recurrent UTIs. A recent…”
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Whole-Genome Sequencing of Mycobacterium tuberculosis Provides Insight into the Evolution and Genetic Composition of Drug-Resistant Tuberculosis in Belarus by Wollenberg, Kurt R, Desjardins, Christopher A, Zalutskaya, Aksana, Slodovnikova, Vervara, Oler, Andrew J, Quiñones, Mariam, Abeel, Thomas, Chapman, Sinead B, Tartakovsky, Michael, Gabrielian, Andrei, Hoffner, Sven, Skrahin, Aliaksandr, Birren, Bruce W, Rosenthal, Alexander, Skrahina, Alena, Earl, Ashlee M

“…The emergence and spread of drug-resistant Mycobacterium tuberculosis (DR-TB) are critical global health issues. Eastern Europe has some of the highest…”
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Pathogenomics of Culex quinquefasciatus and Meta-Analysis of Infection Responses to Diverse Pathogens by Bartholomay, Lyric C, Waterhouse, Robert M, Mayhew, George F, Campbell, Corey L, Michel, Kristin, Zou, Zhen, Ramirez, Jose L, Das, Suchismita, Alvarez, Kanwal, Arensburger, Peter, Bryant, Bart, Chapman, Sinead B, Dong, Yuemei, Erickson, Sara M, Karunaratne, S.H.P. Parakrama, Kokoza, Vladimir, Kodira, Chinnappa D, Pignatelli, Patricia, Shin, Sang Woon, Vanlandingham, Dana L, Atkinson, Peter W, Birren, Bruce, Christophides, George K, Clem, Rollie J, Hemingway, Janet, Higgs, Stephen, Megy, Karine, Ranson, Hilary, Zdobnov, Evgeny M, Raikhel, Alexander S, Christensen, Bruce M, Dimopoulos, George, Muskavitch, Marc A.T

“…The mosquito Culex quinquefasciatus poses a substantial threat to human and veterinary health as a primary vector of West Nile virus (WNV), the filarial worm…”
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Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women by Worby, Colin J., Schreiber, Henry L., Straub, Timothy J., van Dijk, Lucas R., Bronson, Ryan A., Olson, Benjamin S., Pinkner, Jerome S., Obernuefemann, Chloe L. P., Muñoz, Vanessa L., Paharik, Alexandra E., Azimzadeh, Philippe N., Walker, Bruce J., Desjardins, Christopher A., Chou, Wen-Chi, Bergeron, Karla, Chapman, Sinéad B., Klim, Aleksandra, Manson, Abigail L., Hannan, Thomas J., Hooton, Thomas M., Kau, Andrew L., Lai, H. Henry, Dodson, Karen W., Hultgren, Scott J., Earl, Ashlee M.

“…Recurrent urinary tract infections (rUTIs) are a major health burden worldwide, with history of infection being a significant risk factor. While the gut is a…”
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Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance by Salamzade, Rauf, Manson, Abigail L, Walker, Bruce J, Brennan-Krohn, Thea, Worby, Colin J, Ma, Peijun, He, Lorrie L, Shea, Terrance P, Qu, James, Chapman, Sinéad B, Howe, Whitney, Young, Sarah K, Wurster, Jenna I, Delaney, Mary L, Kanjilal, Sanjat, Onderdonk, Andrew B, Bittencourt, Cassiana E, Gussin, Gabrielle M, Kim, Diane, Peterson, Ellena M, Ferraro, Mary Jane, Hooper, David C, Shenoy, Erica S, Cuomo, Christina A, Cosimi, Lisa A, Huang, Susan S, Kirby, James E, Pierce, Virginia M, Bhattacharyya, Roby P, Earl, Ashlee M

“…Carbapenem-resistant Enterobacterales (CRE) are an urgent global health threat. Inferring the dynamics of local CRE dissemination is currently limited by our…”
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Rare coding variants in ten genes confer substantial risk for schizophrenia by Singh, Tarjinder, Poterba, Timothy, Curtis, David, Akil, Huda, Al Eissa, Mariam, Barchas, Jack D., Bass, Nicholas, Bigdeli, Tim B., Breen, Gerome, Bromet, Evelyn J., Buckley, Peter F., Bunney, William E., Bybjerg-Grauholm, Jonas, Byerley, William F., Chapman, Sinéad B., Chen, Wei J., Churchhouse, Claire, Craddock, Nicholas, DeLisi, Lynn, Dodge, Sheila, Escamilla, Michael A., Eskelinen, Saana, Fanous, Ayman H., Faraone, Stephen V., Fiorentino, Alessia, Francioli, Laurent, Gabriel, Stacey B., Gage, Diane, Gagliano Taliun, Sarah A., Ganna, Andrea, Genovese, Giulio, Grove, Jakob, Hall, Mei-Hua, Heyne, Henrike O., Holi, Matti, Hougaard, David M., Howrigan, Daniel P., Huang, Hailiang, Hwu, Hai-Gwo, Kahn, René S., Kang, Hyun Min, Karczewski, Konrad J., Knowles, James A., Lee, Francis S., Lehrer, Douglas S., Lescai, Francesco, Marder, Stephen R., McCarroll, Steven A., McIntosh, Andrew M., Milani, Lili, Morley, Christopher P., Morris, Derek W., Mortensen, Preben Bo, Nordentoft, Merete, O’Brien, Niamh L., Olivares, Ana Maria, Ongur, Dost, Ouwehand, Willem H., Palmer, Duncan S., Paunio, Tiina, Quested, Digby, Rapaport, Mark H., Rees, Elliott, Rollins, Brandi, Satterstrom, F. Kyle, Schatzberg, Alan, Scolnick, Edward, Scott, Laura J., Sharp, Sally I., Sklar, Pamela, Smoller, Jordan W., Solomonson, Matthew, Stahl, Eli A., Stevens, Christine R., Suvisaari, Jaana, Watts, Nicholas A., Blackwood, Douglas H., Cohen, Bruce M., Corvin, Aiden P., Esko, Tõnu, Freimer, Nelson B., Glatt, Stephen J., Hultman, Christina M., McQuillin, Andrew, Palotie, Aarno, Pato, Carlos N., Pato, Michele T., Pulver, Ann E., St. Clair, David, Tsuang, Ming T., Vawter, Marquis P., Walters, James T., Werge, Thomas M., Ophoff, Roel A., Sullivan, Patrick F., Owen, Michael J., Boehnke, Michael, O’Donovan, Michael C., Neale, Benjamin M., Daly, Mark J.

“…Rare coding variation has historically provided the most direct connections between gene function and disease pathogenesis. By meta-analysing the whole exomes…”
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Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry by Bigdeli, Tim B., Genovese, Giulio, Georgakopoulos, Penelope, Meyers, Jacquelyn L., Peterson, Roseann E., Iyegbe, Conrad O., Medeiros, Helena, Valderrama, Jorge, Achtyes, Eric D., Kotov, Roman, Stahl, Eli A., Abbott, Colony, Azevedo, Maria Helena, Belliveau, Richard A., Bevilacqua, Elizabeth, Bromet, Evelyn J., Byerley, William, Carvalho, Celia Barreto, Chapman, Sinéad B., DeLisi, Lynn E., Dumont, Ashley L., O’Dushlaine, Colm, Evgrafov, Oleg V., Fochtmann, Laura J., Gage, Diane, Kennedy, James L., Kinkead, Becky, Macedo, Antonio, Moran, Jennifer L., Morley, Christopher P., Dewan, Mantosh J., Nemesh, James, Perkins, Diana O., Purcell, Shaun M., Rakofsky, Jeffrey J., Scolnick, Edward M., Sklar, Brooke M., Sklar, Pamela, Smoller, Jordan W., Sullivan, Patrick F., Macciardi, Fabio, Marder, Stephen R., Gur, Ruben C., Gur, Raquel E., Braff, David L., Nicolini, Humberto, Escamilla, Michael A., Vawter, Marquis P., Sobell, Janet L., Malaspina, Dolores, Lehrer, Douglas S., Buckley, Peter F., Rapaport, Mark H., Knowles, James A., Fanous, Ayman H., Pato, Michele T., McCarroll, Steven A., Pato, Carlos N.

“…Schizophrenia is a common, chronic and debilitating neuropsychiatric syndrome affecting tens of millions of individuals worldwide. While rare genetic variants…”
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Draft Genome Sequences of Two Extensively Drug-Resistant Strains of Mycobacterium tuberculosis Belonging to the Euro-American S Lineage by Malinga, Lesibana A, Abeel, Thomas, Desjardins, Christopher A, Dlamini, Talent C, Cassell, Gail, Chapman, Sinéad B, Birren, Bruce W, Earl, Ashlee M, van der Walt, Martie

“…We report the whole-genome sequencing of two extensively drug-resistant tuberculosis strains belonging to the Euro-American S lineage. The RSA 114 strain…”
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