Search Results - "CHANGWAN HONG"

New insight of square stepping exercise in immune fine-tuning for anticipating emerging pandemics by Cha, Hyo-Jeong, Hong, Changwan

“…The COVID-19 pandemic has significantly impacted human life, posing serious physical and psychological threats, particularly to the elderly. While individuals…”
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Protein abundance of the cytokine receptor γc controls the thymic generation of innate-like T cells by Park, Joo-Young, Won, Hee Yeun, DiPalma, Devon T., Hong, Changwan, Park, Jung-Hyun

“…Innate-like T (iT) cells comprise a population of immunoregulatory T cells whose effector function is imposed during their development in the thymus to provide…”
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Defects in aminoacyl-tRNA synthetase cause partial B and T cell immunodeficiency by Shim, Ju A., Jo, Yuna, Hwang, Hyunju, Lee, So Eun, Ha, Dahyeon, Lee, Jun Hwa, Kim, Jayoung, Song, Parkyong, Lee, Dongjun, Hong, Changwan

“…Aminoacyl-tRNA synthetases (ARSs) are emerging as important regulators in various immune diseases; however, their roles in immune cells remain unclear. In this…”
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MultiGraph: Efficient Graph Processing on GPUs by Changwan Hong, Sukumaran-Rajam, Aravind, Jinsung Kim, Sadayappan, P.

“…High-level GPU graph processing frameworks are an attractive alternative for achieving both high productivity and high performance. Hence, several high-level…”
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New insight of exercise on dementia; combinatory effects of physical and cognitive exercise by Cha, Hyo-Jeong, Park, Jun Hong, Hong, Changwan

“…Background Dementia is a progressive neurological disorder which is clinically characterized by memory loss, behavioral symptoms, and loss of ability to live a…”
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Variants of innate CD8+ T cells are associated with Grip2 and Klf15 genes by Jo, Yuna, Balmer, Lois, Lee, Byunghyuk, Shim, Ju A, Ali, Laraib Amir, Morahan, Grant, Hong, Changwan

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Identification of alternatively spliced Il7r transcripts in mouse T cells that encode soluble IL-7Rα by Won, Hee Yeun, Jo, Yuna, Shim, Ju A, Hong, Changwan, Park, Jung-Hyun

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NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells by Shim, Ju A, Lee, So Min, Jeong, Jin Woo, Kim, Hyori, Son, Woo Jae, Park, Jun Hong, Song, Parkyong, Im, Sin-Hyeog, Bae, Sangsu, Park, Jung-Hyun, Jo, Yuna, Hong, Changwan

“…IntroductionCytokines of the common γ chain (γc) family are critical for the development, differentiation, and survival of T lineage cells. Cytokines play key…”
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The Potential Role of a Soluble γ-Chain Cytokine Receptor as a Regulator of IL-7-Induced Lymphoproliferative Disorders by Kim, Geona, Jo, Yuna, Lee, Byunghyuk, Ali, Laraib Amir, Lee, Boae, Hong, Changwan

“…IL-7 is an essential, nonredundant growth factor for T and B cell generation and maintenance. While IL-7 deficiency results in lymphopenia, overexpression of…”
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Specific Inhibition of Soluble γc Receptor Attenuates Collagen-Induced Arthritis by Modulating the Inflammatory T Cell Responses by Lee, Byunghyuk, Jo, Yuna, Kim, Geona, Ali, Laraib Amir, Sohn, Dong Hyun, Lee, Seung-Geun, Kim, Kiseok, Shin, Euisu, Ryu, Sung Ho, Hong, Changwan

“…IL-17 produced by Th17 cells has been implicated in the pathogenesis of rheumatoid arthritis (RA). It is important to prevent the differentiation of Th17 cells…”
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Novel endogenous endoplasmic reticulum transmembrane protein SURF4 suppresses cell death by negatively regulating the STING‐STAT6 axis in myeloid leukemia by Kim, Jayoung, Lee, Hansong, Hong, Chae Mi, Nam, Ji Ho, Yeo, Hye Ju, Cho, Woo Hyun, Kim, Hyung‐Sik, Hong, Changwan, Kim, Yun Hak, Lee, Dongjun

“…Abbreviations ROS Reactive oxygen species ER endoplasmic reticulum STING stimulator of interferon genes STAT6 signal transducer and activator of transcription…”
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Resource conscious reuse-driven tiling for GPUs by Rawat, Prashant Singh, Changwan Hong, Ravishankar, Mahesh, Grover, Vinod, Pouchet, Louis-Noel, Rountev, Atanas, Sadayappan, P.

“…Computations involving successive application of 3D stencil operators are widely used in many application domains, such as image processing, computational…”
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Dependence of Elevated Temperature Intergranular Cracking on Grain Size and Bulk Sulfur Content in TP347H Austenitic Stainless Steels by Heo, Nam Hoe, Hong, Changwan, Heo, Yoon-Uk, Kang, Myung Hoon, Yoo, Keun Bong, Kim, Sung-Joon

“…Regardless of the bulk sulfur content, heat–resistant TP347H austenitic stainless steels of the smaller grain size show a ductile fracture after rupture test,…”
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The Cytokine Receptor IL-7Rα Impairs IL-2 Receptor Signaling and Constrains the In Vitro Differentiation of Foxp3+ Treg Cells by Waickman, Adam T., Keller, Hilary R., Kim, Tae-Hyoun, Luckey, Megan A., Tai, Xuguang, Hong, Changwan, Molina-París, Carmen, Walsh, Scott T.R., Park, Jung-Hyun

“…IL-7 receptor signaling is essential for the generation and maintenance of conventional T cells. Immunosuppressive Foxp3+ Treg cells, however, express uniquely…”
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IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex by Yoon, Sik, Lee, Jung Sub, Hong, Changwan, Oh, Sae-Ock, Kang, Seung Wan, Ko, Eunhee, Hwang, Hyunju, Kim, Geona, Lee, Byunghyuk, Jo, Yuna, Goh, Tae Sik, Baek, Sun-Yong

“…IL-7 signaling via IL-7Rα and common γ-chain (γc) is necessary for the development and homeostasis of T cells. Although the delicate mechanism in which IL-7Rα…”
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HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127 by HASLEY, Rebecca B, CHANGWAN HONG, SNELLER, Michael C, OGUARIRI, Raphael, IMAMICHI, Tomozumi, LANE, H. Clifford, CATALFAMO, Marta, WENQING LI, FRIESEN, Travis, NAKAMURA, Yoriko, KIM, Grace Y, PARK, Jung-Hyun, HIXON, Julie A, DURUM, Scott, ZONGHUI HU

“…During HIV infection distinct mechanisms drive immune activation of the CD4 and CD8 T cells leading to CD4 T-cell depletion and expansion of the CD8 T-cell…”
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Regulation of Secondary Antigen-Specific CD8+ T-Cell Responses by Natural Killer T Cells by CHANGWAN HONG, LEE, Hyunji, PARK, Yoon-Kyung, SHIN, Junghoon, SUNDO JUNG, KIM, Hoyeon, HONG, Seokmann, PARK, Se-Ho

“…The physiologic function of natural killer T (NKT) cells in adaptive immunity remains largely unknown because most studies have used NKT cell agonists. In the…”
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Asthma is induced by intranasal coadministration of allergen and natural killer T-cell ligand in a mouse model by Kim, Jae-Ouk, Kim, Dong-Hyeon, Chang, Woo-Sung, Hong, Changwan, Park, Se-Ho, Kim, Sanghee, Kang, Chang-Yuil

“…Allergic asthma is an inflammatory lung disease caused by a TH2-driven immune response. However, intranasal exposures to soluble antigen lead to mucosal…”
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The presence of CD8+ invariant NKT cells in mice by Lee, Hyunji, Hong, Changwan, Shin, Junghoon, Oh, Soohwan, Jung, Sundo, Park, Yoon-Kyung, Hong, Seokmann, Lee, Gap Ryol, Park, Se-Ho

“…Invariant natural killer T (iNKT) cells develop in the thymus upon recognition of CD1d expressed on developing thymocytes. Although CD4 and CD8 coreceptors are…”
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The role of gut microbiota in T cell immunity and immune mediated disorders by Shim, Ju A, Ryu, Jeong Ha, Jo, Yuna, Hong, Changwan

“…Gut microbiota was only considered as a commensal organism that aids in digestion, but recent studies revealed that the microbiome play a critical role in both…”
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