Search Results - "CHANG, J. Judy"
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The Pathway To Establishing HIV Latency Is Critical to How Latency Is Maintained and Reversed
Published in Journal of virology (01-07-2018)“…HIV infection requires lifelong antiretroviral therapy because of the persistence of latently infected CD4 T cells. The induction of virus expression from…”
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Innate Immune Activation in Primary HIV-1 Infection
Published in The Journal of infectious diseases (15-10-2010)“…There is growing evidence that highlights the role of the immune response during acute human immunodeficiency virus type 1 (HIV-1) infection in the control or…”
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Journal Article Conference Proceeding -
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Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1
Published in Nature medicine (01-08-2009)“…Manifestations of viral infections can differ between women and men, and marked sex differences have been described in the course of HIV-1 disease…”
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Higher Expression of Several Interferon-Stimulated Genes in HIV-1-Infected Females After Adjusting for the Level of Viral Replication
Published in The Journal of infectious diseases (01-09-2013)“…Background. Clinical studies have shown faster disease progression and stronger immune activation in human immunodeficiency virus (HIV)-1-infected females when…”
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Immunopathogenesis of hepatitis B virus infection
Published in Immunology and cell biology (01-01-2007)“…Hepatitis B virus (HBV) infection is a non‐cytopathic hepatotropic virus that can lead to severe liver disease including acute hepatitis, cirrhosis and…”
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Diverse effects of interferon alpha on the establishment and reversal of HIV latency
Published in PLoS pathogens (28-02-2020)“…HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived…”
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HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways
Published in AIDS (London) (23-10-2013)“…OBJECTIVE:To study the cytokine/chemokine profiles in response to HIV-1 viremia, and elucidate the pathways leading to HIV-1-induced inflammation…”
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Immune Activation and the Role of TLRs and TLR Agonists in the Pathogenesis of HIV-1 Infection in the Humanized Mouse Model
Published in The Journal of infectious diseases (15-11-2013)“…Immune activation plays a critical role in HIV-1 pathogenesis, but the pathways that are responsible for HIV-1-associated immune activation are not well…”
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Immunopathogenesis of Hepatic Flare in HIV/Hepatitis B Virus (HBV)–Coinfected Individuals after the Initiation of HBV-Active Antiretroviral Therapy
Published in The Journal of infectious diseases (01-04-2009)“…BackgroundThe pathogenesis of and risk factors for hepatic flare (HF) after the initiation of hepatitis B virus (HBV)–active antiretroviral therapy (ART) in…”
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Longitudinal analysis of subtype C envelope tropism for memory CD4+ T cell subsets over the first 3 years of untreated HIV-1 infection
Published in Retrovirology (06-08-2020)“…Abstract Background HIV-1 infects a wide range of CD4 + T cells with different phenotypic properties and differing expression levels of entry coreceptors. We…”
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Effect of high dose vitamin D3 on the HIV-1 reservoir: A pilot randomised controlled trial
Published in Journal of Virus Eradication (01-09-2023)“…Introduction: Antiretroviral therapy for people living with HIV-1 must be taken lifelong due to the persistence of latent virus in long-lived and proliferating…”
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Impaired Quality of the Hepatitis B Virus (HBV)-Specific T-Cell Response in Human Immunodeficiency Virus Type 1-HBV Coinfection
Published in Journal of Virology (01-08-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The phenotype of hepatitis B virus–specific T cells differ in the liver and blood in chronic hepatitis B virus infection
Published in Hepatology (Baltimore, Md.) (01-11-2007)“…Hepatitis B virus (HBV)‐specific T cells play a key role in clearance of the virus and in the pathogenesis of liver disease. Peripheral blood (n = 25) and…”
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No Increase in Hepatitis B Virus (HBV)-Specific CD8+ T Cells in Patients with HIV-1-HBV Coinfections following HBV-Active Highly Active Antiretroviral Therapy
Published in Journal of Virology (01-03-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Reduced Hepatitis B Virus (HBV)-Specific CD4+ T-Cell Responses in Human Immunodeficiency Virus Type 1-HBV-Coinfected Individuals Receiving HBV-Active Antiretroviral Therapy
Published in Journal of Virology (01-03-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women
Published in The Journal of immunology (1950) (01-12-2015)“…Increased IFN-α production contributes to the pathogenesis of infectious and autoimmune diseases. Plasmacytoid dendritic cells (pDCs) from females produce more…”
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Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy
Published in The Journal of immunology (1950) (01-01-2022)“…In people with HIV (PWH) on antiretroviral therapy (ART), immune dysfunction persists, including elevated expression of immune checkpoint (IC) proteins on…”
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Persistence of envelopes in different CD4 + T-cell subsets in antiretroviral therapy-suppressed people with HIV
Published in AIDS (London) (01-02-2023)“…Despite suppressive antiretroviral therapy (ART), HIV can persist in a diverse range of CD4+ T-cell subsets. Through longitudinal env sampling from people with…”
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Impact of alemtuzumab on HIV persistence in an HIV-infected individual on antiretroviral therapy with Sezary syndrome
Published in AIDS (London) (24-08-2017)“…To study the effects of alemtuzumab on HIV persistence in an HIV-infected individual on antiretroviral therapy (ART) with Sezary syndrome, a rare malignancy of…”
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