Search Results - "CHANDRAN, K. B"

Flow in prosthetic heart valves: state-of-the-art and future directions by Yoganathan, Ajit P, Chandran, K B, Sotiropoulos, Fotis

“…Since the first successful implantation of a prosthetic heart valve four decades ago, over 50 different designs have been developed including both mechanical…”
Get full text

Micro-scale Dynamic Simulation of Erythrocyte–Platelet Interaction in Blood Flow by AlMomani, T., Udaykumar, H. S., Marshall, J. S., Chandran, K. B.

“…Platelet activation, adhesion, and aggregation on the blood vessel and implants result in the formation of mural thrombi. Platelet dynamics in blood flow is…”
Get full text

Two-dimensional simulation of flow and platelet dynamics in the hinge region of a mechanical heart valve by Govindarajan, V, Udaykumar, H S, Chandran, K B

“…The hinge region of a mechanical bileaflet valve is implicated in blood damage and initiation of thrombus formation. Detailed fluid dynamic analysis in the…”
Get more information

Towards Non-thrombogenic Performance of Blood Recirculating Devices by Bluestein, D., Chandran, K. B., Manning, K. B.

“…Implantable blood recirculating devices have provided life saving solutions to patients with severe cardiovascular diseases. However, common problems of…”
Get full text

Fluid dynamic analysis in a human left anterior descending coronary artery with arterial motion by Ramaswamy, S D, Vigmostad, S C, Wahle, A, Lai, Y G, Olszewski, M E, Braddy, K C, Brennan, T M H, Rossen, J D, Sonka, M, Chandran, K B

“…A computational fluid dynamic (CFD) analysis is pre sented to describe local flow dynamics in both 3-D spatial and 4-D spatial and temporal domains from…”
Get full text

Three-dimensional finite element analysis of residual stress in arteries by Raghavan, M L, Trivedi, S, Nagaraj, A, McPherson, D D, Chandran, K B

“…Calculation of residual stress in arteries, using the analytical approach has been quite valuable in our understanding of its critical role in vascular…”
Get full text

Pulsatile flow simulation in arterial vascular segments with intravascular ultrasound images by Liu, Y., Lai, Y., Nagaraj, A., Kane, B., Hamilton, A., Greene, R., McPherson, D.D., Chandran, K.B.

“…Previous studies have indicated a correlation between local variation in wall shear stress in arterial blood flow and atheroma development. The purpose of this…”
Get full text

A method for in-vivo analysis for regional arterial wall material property alterations with atherosclerosis: preliminary results by Chandran, K.B., Mun, J.H., Choi, K.K., Chen, J.S., Hamilton, A., Nagaraj, A., McPherson, D.D.

“…Atherosclerosis is a diffuse arterial disease developing over many years and resulting in a complicated three-dimensional arterial morphology. The arterial…”
Get full text

Flow dynamics in the human aorta by Chandran, K B

“…The aorta is the major blood vessel transporting blood pumped by the left ventricle to the systemic circulation. The tricuspid aortic value at the root of the…”
Get more information

Numerical study on the effect of secondary flow in the human aorta on local shear stresses in abdominal aortic branches by Shipkowitz, Tanya, Rodgers, V.G.J., Frazin, Lee J., Chandran, K.B.

“…Flow in the aortic arch is characterized primarily by the presence of a strong secondary flow superimposed over the axial flow, skewed axial velocity profiles…”
Get full text

Comparison of left anterior descending coronary artery hemodynamics before and after angioplasty by Ramaswamy, S D, Vigmostad, S C, Wahle, A, Lai, Y G, Olszewski, M E, Braddy, K C, Brennan, T M H, Rossen, J D, Sonka, M, Chandran, K B

“…Coronary artery disease (CAD) is characterized by the progression of atherosclerosis, a complex pathological process involving the initiation, deposition,…”
Get more information

Numerical simulation of mechanical mitral heart valve closure by Aluri, S, Chandran, K B

“…A computational fluid dynamic simulation of a mechanical heart valve closing dynamics in the mitral position was performed in order to delineate the fluid…”
Get full text

Negative pressure transients with mechanical heart-valve closure : Correlation between in vitro and in vivo results by CHANDRAN, K. B, DEXTER, E. U, ALURI, S, RICHENBACHER, W. E

“…Negative pressure transients (NPT) recorded in a single closing event of mechanical valves in the mitral position in an in vitro setup are compared with data…”
Get full text

Two-dimensional dynamic simulation of platelet activation during mechanical heart valve closure by Krishnan, S, Udaykumar, H S, Marshall, J S, Chandran, K B

“…A major drawback in the operation of mechanical heart valve prostheses is thrombus formation in the near valve region. Detailed flow analysis in this region…”
Get full text

Cavitation dynamics of medtronic hall mechanical heart valve prosthesis: fluid squeezing effect by Lee, C S, Chandran, K B, Chen, L D

“…The cause of cavitation in mechanical heart valves is investigated with Medtronic Hall tilting disk valves in an in vitro flow system simulating the closing…”
Get more information

Functional chiral asymmetry in descending thoracic aorta by FRAZIN, L. J, LANZA, G, VONESH, M, KHASHO, F, SPITZZERI, C, MCGEE, S, MEHLMAN, D, CHANDRAN, K. B, TALANO, J, MCPHERSON, D

“…To determine whether rotational blood flow or chiral asymmetry exists in the human descending thoracic aorta, we established the ability of color Doppler…”
Get full text

Cavitation dynamics of mechanical heart valve prostheses by Lee, C S, Chandran, K B, Chen, L D

“…Nine different mechanical mitral heart valves were chosen in order to study cavitation dynamics in detail in an in vitro flow system simulating a single event…”
Get more information

Image-based point-cloud Hamiltonian dynamic analysis for biomechanical systems by Nadareyshvili, A. I., Chandran, K. B., Lu, Jia

“…The paper presents a discrete method for the dynamic analysis of biomechanical systems. The method works directly on a point‐cloud representation of a material…”
Get full text

Computation of vascular flow dynamics from intravascular ultrasound images by Chandran, K.B., Vonesh, M.J., Roy, A., Greenfield, S., Kane, B., Greene, R., McPherson, D.D.

“…Analysis of three-dimensional velocity profiles and wall shear stress distribution in a segment of an artery reconstructed from in vivo imaging data are…”
Get full text

Mechanical valve closing dynamics : Relationship between velocity of closing, pressure transients, and cavitation initiation by KRISHNAN BALA CHANDRAN, ALURI, S

“…In this study, the closing dynamics of mechanical heart valves was experimentally analyzed with the valves mounted in the mitral position of an in vitro flow…”
Get full text