Search Results - "CHANDRAMOULI, Gadisetti V. R"
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Radiation-Induced Senescence Reprograms Secretory and Metabolic Pathways in Colon Cancer HCT-116 Cells
Published in International journal of molecular sciences (01-05-2021)“…Understanding the global metabolic changes during the senescence of tumor cells can have implications for developing effective anti-cancer treatment…”
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EPR‐based oximetric imaging: a combination of single point‐based spatial encoding and T1 weighting
Published in Magnetic resonance in medicine (01-11-2018)“…Purpose Spin‐lattice relaxation rate (R1)‐based time‐domain EPR oximetry is reported for in vivo applications using a paramagnetic probe, a trityl‐based Oxo71…”
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3
Ornithine decarboxylase as a therapeutic target for endometrial cancer
Published in PloS one (14-12-2017)“…Ornithine Decarboxylase (ODC) a key enzyme in polyamine biosynthesis is often overexpressed in cancers and contributes to polyamine-induced cell proliferation…”
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4
Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation
Published in Cancer research (Chicago, Ill.) (15-04-2007)“…Studies were conducted to determine whether gene expression profiles following a single dose of radiation would yield equivalent profiles following…”
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Concentration-dependent effects of genistein on global gene expression in MCF-7 breast cancer cells: an oligo microarray study
Published in Breast cancer research and treatment (01-07-2008)“…Breast cancer is the most commonly diagnosed cancer among US women; there is therefore great interest in developing preventive and treatment strategies for…”
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Evaluation of a deuterated triarylmethyl spin probe for in vivo R2∗‐based EPR oximetric imaging with enhanced dynamic range
Published in Magnetic resonance in medicine (01-01-2024)“…Purpose In this study, we compared two triarylmethyl (TAM) spin probes, Ox071 and Ox063 for their efficacy in measuring tissue oxygen levels under hypoxic and…”
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Global Expression Analysis of Cancer/Testis Genes in Uterine Cancers Reveals a High Incidence of BORIS Expression
Published in Clinical cancer research (15-03-2007)“…Purpose: Cancer/testis (CT) genes predominantly expressed in the testis (germ cells) and generally not in other normal tissues are aberrantly expressed in…”
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The In vitro and In vivo Effects of Re-Expressing Methylated von Hippel-Lindau Tumor Suppressor Gene in Clear Cell Renal Carcinoma with 5-Aza-2′-deoxycytidine
Published in Clinical cancer research (15-10-2004)“…Purpose: Clear cell renal carcinoma (ccRCC) is strongly associated with loss of the von Hippel-Lindau ( VHL ) tumor suppressor gene. The VHL gene is…”
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Gene Expression Profiles of Serous, Endometrioid, and Clear Cell Subtypes of Ovarian and Endometrial Cancer
Published in Clinical cancer research (15-09-2005)“…Purpose: The presence of similar histologic subtypes of epithelial ovarian and endometrial cancers has long been noted, although the relevance of this finding…”
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PEGPH20, a PEGylated human hyaluronidase, induces radiosensitization by reoxygenation in pancreatic cancer xenografts. A molecular imaging study
Published in Neoplasia (New York, N.Y.) (01-08-2022)“…PEGylated human hyaluronidase (PEGPH20) enzymatically depletes hyaluronan, an important component of the extracellular matrix, increasing the delivery of…”
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Gene expression in uterine leiomyoma from tumors likely to be growing (from black women over 35) and tumors likely to be non-growing (from white women over 35)
Published in PloS one (13-06-2013)“…The study of uterine leiomyomata (fibroids) provides a unique opportunity to investigate the physiological and molecular determinants of hormone dependent…”
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2-Methoxyestradiol Induces Mammary Gland Differentiation through Amphiregulin-Epithelial Growth Factor Receptor-Mediated Signaling: Molecular Distinctions from the Mammary Gland of Pregnant Mice
Published in Endocrinology (Philadelphia) (01-03-2007)“…Levels of 2-methoxyestradiol (2ME2), an endogenous metabolite of estradiol, are highly elevated during late stages of pregnancy when mammary glands have…”
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13
Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection
Published in Cancer research (Chicago, Ill.) (01-06-2006)“…Tumor hypoxia often directly correlates with aggressive phenotype, metastasis progression, and resistance to chemotherapy. Two transcription factors…”
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Dose‐dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin‐like growth factor‐1
Published in Cancer medicine (Malden, MA) (01-10-2012)“…The prevalence of obesity, an established risk and progression factor for breast and many other cancer types, remains very high in the United States and…”
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Cancers as wounds that do not heal : Differences and similarities between renal regeneration/repair and renal cell carcinoma
Published in Cancer research (Chicago, Ill.) (15-07-2006)“…Cancers have been described as wounds that do not heal, suggesting that the two share common features. By comparing microarray data from a model of renal…”
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Gene Expression Profiles Associated with Response to Chemotherapy in Epithelial Ovarian Cancers
Published in Clinical cancer research (01-09-2005)“…Purpose: The goal of this study was to determine whether distinct gene expression profiles are associated with intrinsic and/or acquired chemoresistance in…”
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Evaluation of partial k-space strategies to speed up time-domain EPR imaging
Published in Magnetic resonance in medicine (01-09-2013)“…Narrow‐line spin probes derived from the trityl radical have led to the development of fast in vivo time‐domain EPR imaging. Pure phase‐encoding imaging…”
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Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: Correlation to human disease
Published in Cancer research (Chicago, Ill.) (01-09-2004)“…FVB/N-Tg (MMTV-PyMT)(634Mul)-transgenic mice develop multifocal mammary tumors with a high incidence of pulmonary metastasis. We have demonstrated previously…”
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Estimation of tumor microvessel density by MRI using a blood pool contrast agent
Published in International journal of oncology (01-10-2009)“…Recognition of importance of angiogenesis to tumor growth, metastasis, and treatment outcome has led to efforts to develop non-invasive methods for…”
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Evaluation of a deuterated triarylmethyl spin probe for in vivo R 2 ∗-based EPR oximetric imaging with enhanced dynamic range
Published in Magnetic resonance in medicine (01-01-2024)“…In this study, we compared two triarylmethyl (TAM) spin probes, Ox071 and Ox063 for their efficacy in measuring tissue oxygen levels under hypoxic and normoxic…”
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