Search Results - "CHAN, S. W"

Ultrasound Assessment of Gastric Content and Volume by PERLAS, Anahi, CHAN, Vincent W. S, LUPU, Catalin M, MITSAKAKIS, Nicholas, HANBIDGE, Anthony

“…Aspiration of gastric contents can be a serious perioperative complication, attributing up to 9% of all anesthesia-related deaths. However, there is currently…”
Get full text

AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma by Xu, M Z, Chan, S W, Liu, A M, Wong, K F, Fan, S T, Chen, J, Poon, R T, Zender, L, Lowe, S W, Hong, W, Luk, J M

“…Yes-associated protein (YAP) is a downstream effector of the Hippo signaling pathway, which controls organ expansion and tissue development. We have recently…”
Get full text

Neurological Complications After Regional Anesthesia: Contemporary Estimates of Risk by Brull, Richard, McCartney, Colin J. L., Chan, Vincent W. S., El-Beheiry, Hossam

“…Regional anesthesia (RA) provides excellent anesthesia and analgesia for many surgical procedures. Anesthesiologists and patients must understand the risks in…”
Get full text

Towards a transgenic model of Huntington's disease in a non-human primate by Chan, Anthony W. S, Yang, Shang-Hsun, Cheng, Pei-Hsun, Banta, Heather, Piotrowska-Nitsche, Karolina, Yang, Jin-Jing, Cheng, Eric C. H, Snyder, Brooke, Larkin, Katherine, Liu, Jun, Orkin, Jack, Fang, Zhi-Hui, Smith, Yoland, Bachevalier, Jocelyne, Zola, Stuart M, Li, Shi-Hua, Li, Xiao-Jiang

“…Non-human primates are valuable for modelling human disorders and for developing therapeutic strategies; however, little work has been reported in establishing…”
Get full text

Corneal confocal microscopy detects neuropathy in patients with type 1 diabetes without retinopathy or microalbuminuria by Petropoulos, Ioannis N, Green, Patrick, Chan, Agnes W S, Alam, Uazman, Fadavi, Hassan, Marshall, Andrew, Asghar, Omar, Efron, Nathan, Tavakoli, Mitra, Malik, Rayaz A

“…Corneal innervation is increasingly used as a surrogate marker of human diabetic peripheral neuropathy (DPN) however its temporal relationship with the other…”
Get full text

Cerium and yttrium oxide nanoparticles are neuroprotective by Schubert, David, Dargusch, Richard, Raitano, Joan, Chan, Siu-Wai

“…The responses of cells exposed to nanoparticles have been studied with regard to toxicity, but very little attention has been paid to the possibility that some…”
Get full text

Progress and Prospects for Genetic Modification of Nonhuman Primate Models in Biomedical Research by Chan, Anthony W. S.

“…The growing interest of modeling human diseases using genetically modified (transgenic) nonhuman primates (NHPs) is a direct result of NHPs (rhesus macaque,…”
Get full text

miR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington's Disease Monkey Neural Cells by Kunkanjanawan, Tanut, Carter, Richard L, Prucha, Melinda S, Yang, Jinjing, Parnpai, Rangsun, Chan, Anthony W S

“…Huntington's disease (HD) is an inherited neurodegenerative disorder caused by the expansion of polyglutamine (polyQ) tract that leads to motor, cognitive and…”
Get full text

Amelioration of Huntington's disease phenotype in astrocytes derived from iPSC-derived neural progenitor cells of Huntington's disease monkeys by Cho, In Ki, Yang, Bo, Forest, Craig, Qian, Lu, Chan, Anthony W S

“…Huntington's disease (HD) is a devastating monogenic, dominant, hereditary, neurodegenerative disease. HD is caused by the expansion of CAG repeats in exon 1…”
Get full text

Three-dimensional culture models of human endometrium for studying trophoblast-endometrium interaction during implantation by Li, Xintong, Kodithuwakku, Suranga P, Chan, Rachel W. S, Yeung, William S. B, Yao, Yuanqing, Ng, Ernest H. Y, Chiu, Philip C. N, Lee, Cheuk-Lun

“…Abstract During implantation, a symphony of interaction between the trophoblast originated from the trophectoderm of the implanting blastocyst and the…”
Get full text

Progressive cognitive deficit, motor impairment and striatal pathology in a transgenic Huntington disease monkey model from infancy to adulthood by Chan, Anthony W S, Jiang, Jie, Chen, Yiju, Li, Chunxia, Prucha, Melinda S, Hu, Yijuan, Chi, Tim, Moran, Sean, Rahim, Tayeb, Li, Shihua, Li, Xiaojiang, Zola, Stuart M, Testa, Claudia M, Mao, Hui, Villalba, Rosa, Smith, Yoland, Zhang, Xiaodong, Bachevalier, Jocelyne

“…One of the roadblocks to developing effective therapeutics for Huntington disease (HD) is the lack of animal models that develop progressive clinical traits…”
Get full text

D‐dimer testing in pregnant patients: towards determining the next ‘level’ in the diagnosis of deep vein thrombosis by CHAN, W.‐S., LEE, A., SPENCER, F. A., CHUNILAL, S., CROWTHER, M., WU, W., JOHNSTON, M., RODGER, M., GINSBERG, J. S.

“…Background: The role of D‐dimer in excluding deep vein thrombosis (DVT) in pregnancy is currently uncertain. We hypothesized that the specificity of sensitive…”
Get full text

Experience of clinical services shapes attitudes to mental health data sharing: findings from a UK-wide survey by Kirkham, E J, Lawrie, S M, Crompton, C J, Iveson, M H, Jenkins, N D, Goerdten, J, Beange, I, Chan, S W Y, McIntosh, A, Fletcher-Watson, S

“…Routinely-collected mental health data could deliver novel insights for mental health research. However, patients' willingness to share their mental health…”
Get full text

Does Regional Anesthesia Improve Outcome After Total Knee Arthroplasty? by Macfarlane, Alan J. R., Arun Prasad, Govindarajulu, Chan, Vincent W. S., Brull, Richard

“…Total knee arthroplasty (TKA) is amenable to various regional anesthesia techniques that may improve patient outcome. We sought to answer whether regional…”
Get full text

Fascial Plane Blocks: More Questions Than Answers? by Black, Nick D., Stecco, Carla, Chan, Vincent W. S.

Get full text

Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation by Xu, Shan, Chan, Rachel W S, Li, Tianqi, Ng, Ernest H Y, Yeung, William S B

“…The identification of endometrial stem/progenitor cells in a high turnover rate tissue suggests that a well-orchestrated underlying network controls the…”
Get full text

Worldwide variation in cardiovascular magnetic resonance practice models by Sierra-Galan, Lilia M., Estrada-Lopez, Edgar E.S., Ferrari, Victor A., Raman, Subha V., Ferreira, Vanessa M., Raj, Vimaj, Joseph, Elizabeth, Schulz-Menger, Jeanette, Chan, Carmen W.S., Chen, Sylvia S.M., Cheng, Yuchen, De Lara Fernandez, Juliano, Terashima, Masahiro, Albert, Timothy S.E.

“…The use of cardiovascular magnetic resonance (CMR) for diagnosis and management of a broad range of cardiac and vascular conditions has quickly expanded…”
Get full text

Single-cell RNA sequencing of cultured human endometrial CD140b+CD146+ perivascular cells highlights the importance of in vivo microenvironment by Cao, Dandan, Chan, Rachel W. S, Ng, Ernest H. Y, Gemzell-Danielsson, Kristina, Yeung, William S. B

“…Abstract Background Endometrial mesenchymal-like stromal/stem cells (eMSCs) have been proposed as adult stem cells contributing to endometrial regeneration…”
Get full text

Methods for Estimating the Case Fatality Ratio for a Novel, Emerging Infectious Disease by Ghani, A. C., Donnelly, C. A., Cox, D. R., Griffin, J. T., Fraser, C., Lam, T. H., Ho, L. M., Chan, W. S., Anderson, R. M., Hedley, A. J., Leung, G. M.

“…During the course of an epidemic of a potentially fatal disease, it is important that the case fatality ratio be well estimated. The authors propose a novel…”
Get full text

A review of upper extremity deep vein thrombosis in pregnancy: unmasking the ‘ART’ behind the clot by CHAN, W.‐S., GINSBERG, J. S.

“…Background: Upper extremity deep vein thrombosis (UEDVT) is uncommon and is associated with well‐defined risk factors in the general population. Increasingly,…”
Get full text