Search Results - "CHAN, C. K"
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Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2018)“…Cell-free DNA in human plasma is nonrandomly fragmented and reflects genomewide nucleosomal organization. Previous studies had demonstrated tissue-specific…”
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Cross-Cultural Validation of the Depression Anxiety Stress Scale-21 in China
Published in Psychological assessment (01-05-2016)“…The gap between the demand and delivery of mental health services in mainland China can be reduced by validating freely available and psychometrically sound…”
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Brain Anatomical Abnormalities in High-Risk Individuals, First-Episode, and Chronic Schizophrenia: An Activation Likelihood Estimation Meta-analysis of Illness Progression
Published in Schizophrenia bulletin (01-01-2011)“…The present study reviewed voxel-based morphometry (VBM) studies on high-risk individuals with schizophrenia, patients experiencing their first-episode…”
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4
Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin
Published in Genome research (01-03-2019)“…Cell-free DNA (cfDNA) in human plasma is a class of biomarkers with many current and potential future diagnostic applications. Recent studies have shown that…”
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Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA
Published in Proceedings of the National Academy of Sciences - PNAS (08-01-2019)“…Circulating DNA in plasma consists of short DNA fragments. The biological processes generating such fragments are not well understood. DNASE1L3 is a secreted…”
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6
Pitting initiation in Fe-based amorphous coatings
Published in Acta materialia (01-06-2012)“…Amorphous metallic coatings, especially Fe-based amorphous coatings, are thought to have promising potential for industrial applications in aggressive…”
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7
Impairing existing declarative memory in humans by disrupting reconsolidation
Published in Proceedings of the National Academy of Sciences - PNAS (04-06-2013)“…During the past decade, a large body of research has shown that memory traces can become labile upon retrieval and must be restabilized. Critically,…”
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A Scalable Laser-Assisted Method to Produce Active and Robust Graphene-Supported Nanoparticle Electrocatalysts
Published in Chemistry of materials (08-10-2019)“…The development of renewable energy schemes requires the scalable production of highly robust electrocatalysts using a sustainable synthesis process that does…”
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A Meta-Analysis of Working Memory Impairments in Autism Spectrum Disorders
Published in Neuropsychology review (01-03-2017)“…Autism spectrum disorders (ASD) are characterized by executive dysfunction, and working memory (WM) comprises one core component of executive function. Many…”
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Microfluidics Digital PCR Reveals a Higher than Expected Fraction of Fetal DNA in Maternal Plasma
Published in Clinical chemistry (Baltimore, Md.) (01-10-2008)“…The precise measurement of cell-free fetal DNA in maternal plasma facilitates noninvasive prenatal diagnosis of fetal chromosomal aneuploidies and other…”
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Noninvasive Prenatal Diagnosis of Congenital Adrenal Hyperplasia Using Cell-Free Fetal DNA in Maternal Plasma
Published in The journal of clinical endocrinology and metabolism (01-06-2014)“…Context: Congenital adrenal hyperplasia (CAH) is an autosomal recessive condition that arises from mutations in CYP21A2 gene, which encodes for the…”
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Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2018)“…Circulating tumor-derived DNA testing for cancer screening has recently been demonstrated in a prospective study on identification of nasopharyngeal carcinoma…”
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13
Digital PCR Analysis of Maternal Plasma for Noninvasive Detection of Sickle Cell Anemia
Published in Clinical chemistry (Baltimore, Md.) (01-06-2012)“…Cell-free fetal DNA (cffDNA) constitutes approximately 10% of the cell-free DNA in maternal plasma and is a suitable source of fetal genetic material for…”
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Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing
Published in Clinical chemistry (Baltimore, Md.) (01-01-2013)“…Tumor-derived DNA can be found in the plasma of cancer patients. In this study, we explored the use of shotgun massively parallel sequencing (MPS) of plasma…”
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15
Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex
Published in Scientific reports (27-09-2024)“…We developed a covalent antithrombin-heparin complex (ATH) with superior In vivo anticoagulant efficacy compared to non-covalent antithrombin (AT) +…”
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Neurological Soft Signs in Schizophrenia: A Meta-analysis
Published in Schizophrenia bulletin (01-11-2010)“…Neurological soft signs (NSS) are hypothesized as candidate endophenotypes for schizophrenia, but their prevalence and relations with clinical and demographic…”
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Evaluation of the Effectiveness of Remote Foot Temperature Monitoring for Prevention of Amputation in a Large Integrated Health Care System
Published in Diabetes care (01-08-2023)“…We evaluated the effectiveness of remote foot temperature monitoring (RTM) in the Veterans Affairs health care system. We conducted a retrospective cohort…”
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Schizotypy as an organizing framework for social and affective sciences
Published in Schizophrenia bulletin (01-03-2015)“…Schizotypy, defined in terms of commonly occurring personality traits related to the schizophrenia spectrum, has been an important construct for understanding…”
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Facial emotion processing in schizophrenia: a meta-analysis of functional neuroimaging data
Published in Schizophrenia bulletin (01-09-2010)“…People with schizophrenia have difficulty with emotion perception. Functional imaging studies indicate regional brain activation abnormalities in patients with…”
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Impacts of transboundary air pollution and local emissions on PM2.5 pollution in the Pearl River Delta region of China and the public health, and the policy implications
Published in Environmental research letters (01-03-2019)“…Despite a downward trend in pollutant levels because of a series of emission control policies, the Pearl River Delta (PRD) region continues to suffer from a…”
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