Search Results - "CHALANDON, Yves"

Immunological Basis of Bone Marrow Failure after Allogeneic Hematopoietic Stem Cell Transplantation by Masouridi-Levrat, Stavroula, Simonetta, Federico, Chalandon, Yves

“…Bone marrow failure (BMF) syndromes are severe complications of allogeneic hematopoietic stem cell transplantation (allo-HSCT). In this paper, we distinguish…”
Get full text

Rituximab in B-Lineage Adult Acute Lymphoblastic Leukemia by Maury, Sébastien, Chevret, Sylvie, Thomas, Xavier, Heim, Dominik, Leguay, Thibaut, Huguet, Françoise, Chevallier, Patrice, Hunault, Mathilde, Boissel, Nicolas, Escoffre-Barbe, Martine, Hess, Urs, Vey, Norbert, Pignon, Jean-Michel, Braun, Thorsten, Marolleau, Jean-Pierre, Cahn, Jean-Yves, Chalandon, Yves, Lhéritier, Véronique, Beldjord, Kheira, Béné, Marie C, Ifrah, Norbert, Dombret, Hervé

“…The addition of rituximab to every phase of treatment (induction, consolidation, and maintenance) in adults with acute lymphoblastic leukemia improves…”
Get full text

State-of-the-art review: allogeneic stem cell transplantation for myelofibrosis in 2019 by McLornan, Donal P, Yakoub-Agha, Ibrahim, Robin, Marie, Chalandon, Yves, Harrison, Claire N, Kroger, Nicolaus

“…Advances in understanding the pathogenesis and molecular landscape of myelofibrosis have occurred over the last decade. Treating physicians now have access to…”
Get full text

Antibody responses to SARS-CoV2 vaccination in allogeneic hematopoietic stem cell transplant recipients by Mamez, Anne-Claire, Pradier, Amandine, Giannotti, Federica, Petitpas, Adrien, Urdiola, Marta Fabra, Vu, Diem-Lan, Masouridi-Levrat, Stavroula, Morin, Sarah, Dantin, Carole, Clerc-Renaud, Dominique, Eberhardt, Christiane S., Kaiser, Laurent, Simonetta, Federico, Chalandon, Yves

Get full text

Intensified Therapy of Acute Lymphoblastic Leukemia in Adults: Report of the Randomized GRAALL-2005 Clinical Trial by Huguet, Françoise, Chevret, Sylvie, Leguay, Thibaut, Thomas, Xavier, Boissel, Nicolas, Escoffre-Barbe, Martine, Chevallier, Patrice, Hunault, Mathilde, Vey, Norbert, Bonmati, Caroline, Lepretre, Stéphane, Marolleau, Jean-Pierre, Pabst, Thomas, Rousselot, Philippe, Buzyn, Agnès, Cahn, Jean-Yves, Lhéritier, Véronique, Béné, Marie C, Asnafi, Vahid, Delabesse, Eric, Macintyre, Elizabeth, Chalandon, Yves, Ifrah, Norbert, Dombret, Hervé

“…Purpose To evaluate randomly the role of hyperfractionated cyclophosphamide (hyper-C) dose intensification in adults with newly diagnosed Philadelphia…”
Get full text

Neoantigen-specific T-cell response after donor lymphocyte infusion associates with favorable outcome in a patient with i(12p) germ cell tumor, acute leukemia and sarcoma of the same clonal origin by Genoud, Vassilis, Dutoit, Valérie, Thang, Nhu-Nam Tran, Janowczyk, Andrew, McKee, Thomas, Chalandon, Yves, Tsantoulis, Petros, Dietrich, Pierre-Yves

Get full text

Toward a NOTCH1/FBXW7/RAS/PTEN–Based Oncogenetic Risk Classification of Adult T-Cell Acute Lymphoblastic Leukemia: A Group for Research in Adult Acute Lymphoblastic Leukemia Study by TRINQUAND, Amélie, TANGUY-SCHMIDT, Aline, LHERITIER, Véronique, BOND, Jonathan, HUGUET, Françoise, BUZYN, Agnès, LEGUAY, Thibaud, CAHN, Jean-Yves, THOMAS, Xavier, CHALANDON, Yves, DELANNOY, André, BONMATI, Caroline, BEN ABDELALI, Raouf, MAURY, Sebastien, NADEL, Bertrand, MACINTYRE, Elizabeth, IFRAH, Norbert, DOMBRET, Hervé, ASNAFI, Vahid, LAMBERT, Jérôme, BELDJORD, Kheira, LENGLINE, Etienne, DE GUNZBURG, Noémie, PAYET-BORNET, Dominique, LHERMITTE, Ludovic, MOSSAFA, Hossein

“…The Group for Research in Adult Acute Lymphoblastic Leukemia (GRAALL) recently reported a significantly better outcome in T-cell acute lymphoblastic leukemia…”
Get full text

Pediatric-Inspired Therapy in Adults With Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia: The GRAALL-2003 Study by HUGUET, Francoise, LEGUAY, Thibaut, VERNANT, Jean-Paul, LAFAGE-POCHITALOFF, Marina, CHASSEVENT, Agnès, LHERITIER, Véronique, MACINTYRE, Elizabeth, BENE, Marie-Christine, IFRAH, Norbert, DOMBRET, Hervé, RAFFOUX, Emmanuel, THOMAS, Xavier, BELDJORD, Kheira, DELABESSE, Eric, CHEVALLIER, Patrice, BUZYN, Agnes, DELANNOY, André, CHALANDON, Yves

“…Retrospective comparisons have suggested that adolescents or teenagers with acute lymphoblastic leukemia (ALL) benefit from pediatric rather than adult…”
Get full text

Improved outcome of patients with graft-versus-host disease after allogeneic hematopoietic cell transplantation for hematologic malignancies over time: an EBMT mega-file study by Greinix, Hildegard T, Eikema, Dirk-Jan, Koster, Linda, Penack, Olaf, Yakoub-Agha, Ibrahim, Montoto, Silvia, Chabannon, Christian, Styczynski, Jan, Nagler, Arnon, Robin, Marie, Robinson, Stephen, Chalandon, Yves, Mikulska, Malgorzata, Schönland, Stefan, Peric, Zinaida, Ruggeri, Annalisa, Lanza, Francesco, De Wreede, Liesbeth C, Mohty, Mohamad, Basak, Grzegorz W, Kröger, Nicolaus

“…Acute graft-versus-host disease (aGvHD) remains a major threat to successful outcome following allogeneic hematopoietic cell transplantation though advances in…”
Get full text

Genetic T-cell receptor diversity at 1 year following allogeneic hematopoietic stem cell transplantation by Buhler, Stéphane, Bettens, Florence, Dantin, Carole, Ferrari-Lacraz, Sylvie, Ansari, Marc, Mamez, Anne-Claire, Masouridi-Levrat, Stavroula, Chalandon, Yves, Villard, Jean

“…After allogeneic hematopoietic stem cell transplantation (HSCT), immune reconstitution leads to the development of a new T-cell repertoire. Immune…”
Get full text

DNMT3A mutation is associated with increased age and adverse outcome in adult T-cell acute lymphoblastic leukemia by Bond, Jonathan, Touzart, Aurore, Leprêtre, Stéphane, Graux, Carlos, Bargetzi, Mario, Lhermitte, Ludovic, Hypolite, Guillaume, Leguay, Thibaut, Hicheri, Yosr, Guillerm, Gaëlle, Bilger, Karin, Lhéritier, Véronique, Hunault, Mathilde, Huguet, Françoise, Chalandon, Yves, Ifrah, Norbert, Macintyre, Elizabeth, Dombret, Hervé, Asnafi, Vahid, Boissel, Nicolas

“…The prognostic implications of genotype in T-cell acute lymphoblastic leukemia are incompletely understood. We performed comprehensive genetic and…”
Get full text

Nonmyeloablative Alternative Donor Transplantation for Hodgkin and Non-Hodgkin Lymphoma: From the LWP-EBMT, Eurocord, and CIBMTR by Fatobene, Giancarlo, Rocha, Vanderson, St Martin, Andrew, Hamadani, Mehdi, Robinson, Stephen, Bashey, Asad, Boumendil, Ariane, Brunstein, Claudio, Castagna, Luca, Dominietto, Alida, Finel, Hervé, Chalandon, Yves, Kenzey, Chantal, Kharfan-Dabaja, Mohamed, Labussière-Wallet, Hélène, Moraleda, Jose M, Pastano, Rocco, Perales, Miguel-Angel, El Ayoubi, Hanadi Rafii, Ruggeri, Annalisa, Sureda, Anna, Volt, Fernanda, Yakoub-Agha, Ibrahim, Zhang, Mei-Jie, Gluckman, Eliane, Montoto, Silvia, Eapen, Mary

“…To compare the outcomes of patients with Hodgkin or non-Hodgkin lymphoma undergoing nonmyeloablative haploidentical or unrelated cord blood (UCB) hematopoietic…”
Get full text

Autologous bone marrow mononuclear cell transplantation in patients with decompensated alcoholic liver disease: a randomized controlled trial by Spahr, Laurent, Chalandon, Yves, Terraz, Sylvain, Kindler, Vincent, Rubbia-Brandt, Laura, Frossard, Jean-Louis, Breguet, Romain, Lanthier, Nicolas, Farina, Annarita, Passweg, Jakob, Becker, Christoph D, Hadengue, Antoine

“…Impaired liver regeneration is associated with a poor outcome in patients with decompensated alcoholic liver disease (ALD). We assessed whether autologous bone…”
Get full text

Dynamics of Expression of Programmed Cell Death Protein-1 (PD-1) on T Cells After Allogeneic Hematopoietic Stem Cell Transplantation by Simonetta, Federico, Pradier, Amandine, Bosshard, Carine, Masouridi-Levrat, Stavroula, Dantin, Carole, Koutsi, Aikaterini, Tirefort, Yordanka, Roosnek, Eddy, Chalandon, Yves

“…Immune exhaustion contributes to treatment failure after allogeneic hematopoietic stem cell transplantation (HSCT) for hematological malignancies. Immune…”
Get full text

Clinical Considerations of Isavuconazole Administration in High-Risk Hematological Patients: A Single-Center 5-Year Experience by Kronig, Ilona, Masouridi-Levrat, Stavroula, Chalandon, Yves, Glampedakis, Emmanouil, Vernaz, Nathalie, Van Delden, Christian, Neofytos, Dionysios

“…Background There are limited real-life data on isavuconazole prophylaxis and treatment of invasive mold infections (IMI) in hematological patients and…”
Get full text

Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation by Kim, Rathana, Boissel, Nicolas, Touzart, Aurore, Leguay, Thibaut, Thonier, Florian, Thomas, Xavier, Raffoux, Emmanuel, Huguet, Françoise, Villarese, Patrick, Fourrage, Cécile, Passini, Loïc, Hunault, Mathilde, Lepretre, Stéphane, Chevallier, Patrice, Braun, Thorsten, Lhéritier, Véronique, Chantepie, Sylvain, Maury, Sébastien, Escoffre, Martine, Tavernier, Emmanuelle, Chalandon, Yves, Graux, Carlos, Macintyre, Elizabeth, Ifrah, Norbert, Asnafi, Vahid, Dombret, Hervé, Lhermitte, Ludovic

“…The prognostic value of IL7-receptor pathway (IL7Rp) mutations in T-cell acute lymphoblastic leukemia (T-ALL) remains unclear. We performed a comprehensive…”
Get full text

Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children by Dilo, Ana, Daali, Youssef, Desmeules, Jules, Chalandon, Yves, Uppugunduri, Chakradhara R. S., Ansari, Marc

“…Busulfan (Bu) is one of the conditioning regimen components for pediatric hematopoietic stem cell transplantation. Bu therapeutic drug monitoring (TDM) is…”
Get full text

Real-world experience of sorafenib maintenance after allogeneic hematopoietic stem cell transplantation for FLT3-ITD AML reveals high rates of toxicity-related treatment interruption by Morin, Sarah, Giannotti, Federica, Mamez, Anne-Claire, Pradier, Amandine, Masouridi-Levrat, Stavroula, Simonetta, Federico, Chalandon, Yves

“…Sorafenib significantly improves survival of FLT3-ITD mutated AML patients when used as a post-allogeneic HSCT maintenance. Importantly, clinical trials…”
Get full text

Incidence and outcome of central nervous system relapse after hematopoietic stem cell transplantation in patients suffering from acute myeloid leukemia and acute lymphoblastic leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation by Blum, Sabine, Chalandon, Yves, Labopin, Myriam, Finke, Jürgen, Gedde-Dahl, Tobias, Othman, Tarek Ben, Cornelissen, Jan J, Jindra, Pavel, Labussière-Wallet, Hélène, Collin, Matthew, Lenhoff, Stig, Kobbe, Guido, Gutiérrez, Norma C, Nagler, Arnon, Mohty, Mohamad

Get full text

Granulocyte‐colony stimulating factor induces proliferation of hepatic progenitors in alcoholic steatohepatitis: A randomized trial by Spahr, Laurent, Lambert, Jean‐François, Rubbia‐Brandt, Laura, Chalandon, Yves, Frossard, Jean‐Louis, Giostra, Emiliano, Hadengue, Antoine

“…Liver failure is the major cause of death in alcoholic steatohepatitis (ASH). In experimental hepatitis, granulocyte‐colony stimulating factor (G‐CSF)…”
Get full text