Search Results - "CHAIX, A"

TECRL, a new life‐threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT by Devalla, Harsha D, Gélinas, Roselle, Aburawi, Elhadi H, Beqqali, Abdelaziz, Goyette, Philippe, Freund, Christian, Chaix, Marie‐A, Tadros, Rafik, Jiang, Hui, Le Béchec, Antony, Monshouwer‐Kloots, Jantine J, Zwetsloot, Tom, Kosmidis, Georgios, Latour, Frédéric, Alikashani, Azadeh, Hoekstra, Maaike, Schlaepfer, Jurg, Mummery, Christine L, Stevenson, Brian, Kutalik, Zoltan, de Vries, Antoine AF, Rivard, Léna, Wilde, Arthur AM, Talajic, Mario, Verkerk, Arie O, Al‐Gazali, Lihadh, Rioux, John D, Bhuiyan, Zahurul A, Passier, Robert

“…Genetic causes of many familial arrhythmia syndromes remain elusive. In this study, whole‐exome sequencing (WES) was carried out on patients from three…”
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Increasing Prevalence of Atrial Fibrillation and Permanent Atrial Arrhythmias in Congenital Heart Disease by Labombarda, Fabien, Hamilton, Robert, Shohoudi, Azadeh, Aboulhosn, Jamil, Broberg, Craig S., Chaix, Marie A., Cohen, Scott, Cook, Stephen, Dore, Annie, Fernandes, Susan M., Fournier, Anne, Kay, Joseph, Macle, Laurent, Mondésert, Blandine, Mongeon, François-Pierre, Opotowsky, Alexander R., Proietti, Anna, Rivard, Lena, Ting, Jennifer, Thibault, Bernard, Zaidi, Ali, Khairy, Paul

“…Atrial arrhythmias are the most common complication encountered in the growing and aging population with congenital heart disease. This study sought to assess…”
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Eisenmenger Syndrome: A Multisystem Disorder—Do Not Destabilize the Balanced but Fragile Physiology by Chaix, Marie-A., Gatzoulis, Michael A., Diller, Gerhard-Paul, Khairy, Paul, Oechslin, Erwin N.

“…Eisenmenger syndrome is the most severe and extreme phenotype of pulmonary arterial hypertension associated with congenital heart disease. A large…”
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Impact of Fontan Fenestration on Adverse Cardiovascular Outcomes: A Multicentre Study by Dib, Nabil, Samuel, Michelle, Levesque, Sylvie, Zaidi, Ali, Cohen, Sarah, Opotowsky, Alexander R., Mongeon, François-Pierre, Mondésert, Blandine, Kay, Joseph, Ibrahim, Reda, Hamilton, Robert M., Fournier, Anne, Jameson, Susan M., Dore, Annie, Cook, Stephen C., Cohen, Scott, Chaix, Marie-A., Broberg, Craig S., Aboulhosn, Jamil, Poirier, Nancy, Khairy, Paul

“…Fenestrating a Fontan baffle has been associated with improved perioperative outcomes in patients with univentricular hearts. However, longer-term potential…”
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Late Onset Postcapillary Pulmonary Hypertension in Patients With Transposition of the Great Arteries and Mustard or Senning Baffles by Chaix, Marie‐A., Dore, Annie, Mercier, Lise‐Andrée, Mongeon, François‐Pierre, Marcotte, François, Ibrahim, Réda, Asgar, Anita W., Shohoudi, Azadeh, Labombarda, Fabien, Mondésert, Blandine, Poirier, Nancy, Khairy, Paul

“…Background There is a paucity of data regarding late‐onset pulmonary hypertension (PH) in patients with transposition of the great arteries and atrial switch…”
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The Fontan Circulation: From Ideal to Failing Hemodynamics and Drug Therapies for Optimization by Perrin, Nils, Dore, Annie, van de Bruaene, Alexander, Mongeon, François-Pierre, Mondésert, Blandine, Poirier, Nancy, Miró, Joaquim, Khairy, Paul, Ibrahim, Réda, Chaix, Marie-A.

“…Fontan palliation results in a hemodynamically complex circulation with multisystem consequences, which in the long term adversely affect many body processes…”
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Genetic testing in congenital heart disease:A clinical approach by Chaix, Marie A, Andelfinger, Gregor, Khairy, Paul

“…Congenital heart disease(CHD) is the most common type of birth defect. Traditionally, a polygenic model defined by the interaction of multiple genes and…”
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Arrhythmias in adults with congenital heart disease and heart failure by Bessière, Francis, Mondésert, Blandine, Chaix, Marie-A, Khairy, Paul

“…Arrhythmias and heart failure are among the most common complications encountered by adults with congenital heart disease (CHD). In this contemporary review,…”
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Loss of AF6 afadin, a marker of poor outcome in breast cancer, induces cell migration, invasiveness and tumor growth by Fournier, G, Cabaud, O, Josselin, E, Chaix, A, Adélaïde, J, Isnardon, D, Restouin, A, Castellano, R, Dubreuil, P, Chaffanet, M, Birnbaum, D, Lopez, M

“…Afadin/AF6, an F-actin-binding protein, is ubiquitously expressed in epithelia and has a key role during development, through its regulatory role in cell–cell…”
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A Cultural Capital Perspective of the Effect of a Government–Voluntary Sector Partnership for Enhancing Access to Postsecondary Education by Lund-Chaix, A. A., Gelles, Erna

“…Affordable access to postsecondary education is of growing concern for both families and policy makers. More students have chosen to continue their education…”
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Risks and Benefits of Exercise Training in Adults With Congenital Heart Disease by Chaix, Marie-A, MD, MS, Marcotte, François, MD, Dore, Annie, MD, Mongeon, François-Pierre, MD, MS, Mondésert, Blandine, MD, Mercier, Lise-Andrée, MD, Khairy, Paul, MD, PhD

“…Abstract Exercise capacity in adults with various forms of congenital heart disease is substantially lower than that of the general population. Although the…”
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KIT-D816V oncogenic activity is controlled by the juxtamembrane docking site Y568-Y570 by Chaix, A, Arcangeli, M-L, Lopez, S, Voisset, E, Yang, Y, Vita, M, Letard, S, Audebert, S, Finetti, P, Birnbaum, D, Bertucci, F, Aurrand-Lions, M, Dubreuil, P, De Sepulveda, P

“…Mutation of KIT receptor tyrosine kinase at residue D816 results in ligand-independent constitutive kinase activity. This mutation occurs in most patients with…”
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Cardiovascular Outcomes in Fontan Patients With Right vs Left Univentricular Morphology: A Multicenter Study by Dib, Nabil, Chaix, Marie-A, Samuel, Michelle, Hermann Honfo, Sewanou, Hamilton, Robert M, Aboulhosn, Jamil, Broberg, Craig S, Cohen, Scott, Cook, Stephen, Dore, Annie, Jameson, Susan M, Fournier, Anne, Ibrahim, Reda, Kay, Joseph, Mongeon, François-Pierre, Opotowsky, Alexander R, Zaidi, Ali, Poirier, Nancy, Khairy, Paul

“…There is a paucity of data on long-term outcomes after Fontan palliation in patients with a dominant morphological univentricular right (uRV) vs left (uLV)…”
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Design of the Prospective Comparison of Angiotensin Receptor-Neprilysin Inhibitor Versus Placebo in Patients With Congenital Systemic Right Ventricle Heart Failure (PARACYS-RV) Trial by Chaix, Marie-A., Dore, Annie, Mondésert, Blandine, Mongeon, François-Pierre, Roy, Véronique, Guertin, Marie-Claude, White, Michel, Ibrahim, Réda, O’Meara, Eileen, Rouleau, Jean-Lucien, Khairy, Paul

“…The presence of a systemic right ventricle (sRV) with biventricular physiology (biV) is associated with increased patient morbidity and mortality. To date, no…”
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Characterization of a Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model for the Study of Variant Pathogenicity: Validation of a KCNJ2 Mutation by Gélinas, Roselle, El Khoury, Nabil, Chaix, Marie-A, Beauchamp, Claudine, Alikashani, Azadeh, Ethier, Nathalie, Boucher, Gabrielle, Villeneuve, Louis, Robb, Laura, Latour, Frédéric, Mondesert, Blandine, Rivard, Lena, Goyette, Philippe, Talajic, Mario, Fiset, Céline, Rioux, John David

“…Long-QT syndrome is a potentially fatal condition for which 30% of patients are without a genetically confirmed diagnosis. Rapid identification of causal…”
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The Influence of Illness Perception and Coping on Anxiety in Adults With Congenital Heart Disease by Marcil, Marie-Joëlle, Houchi, Cylia, Nadarajah, Kishani, Khairy, Paul, Mageau, Geneviève A, Marin, Marie-France, Cossette, Mariève, Dubé, Marie-Pierre, Chaix, Marie-A, Mongeon, François-Pierre, Dore, Annie, Mondésert, Blandine, Ibrahim, Reda, Brouillette, Judith

“…Up to one-half of adults with congenital heart disease (CHD) experience psychological distress, including anxiety. This paper sought to: 1) assess the…”
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Palpitations Revealing a Primary Pulmonary Artery Sarcoma by Massie, Emmanuelle, White, Michel, Robillard, Julie, Demers, Philippe, Mondésert, Blandine, Doyon, Josée, Chaix, Marie-A.

“…Primary pulmonary artery sarcoma is an exceedingly rare and aggressive malignancy that carries poor prognosis. Clinical manifestations are nonspecific and…”
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Novel CALM3 mutations in pediatric long QT syndrome patients support a CALM3-specific calmodulinopathy by Chaix, Marie-A., Koopmann, Tamara T., Goyette, Philippe, Alikashani, Azadeh, Latour, Frédéric, Fatah, Meena, Hamilton, Robert M., Rioux, John D.

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Sudden Cardiac Death in Adult Congenital Heart Disease by Ávila, Pablo, MD, Chaix, Marie-A., MD, MS, Mondésert, Blandine, MD, Khairy, Paul, MD, PhD

“…Sudden death of presumed arrhythmic etiology is a leading cause of mortality in adults with congenital heart disease. Anticipated benefits of the implantable…”
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Hands-on Experiments on Glycemia Regulation and Type 1 Diabetes by Mingueneau, M, Chaix, A, Scotti, N, Chaix, J, Reynders, A, Hammond, C, Thimonier, J

“…In the present article, we describe a 3-day experimental workshop on glycemia regulation and type 1 diabetes that engages students in open-ended investigations…”
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