Search Results - "CESSON, Valérie"

Urine biomarkers can predict prostate cancer and PI-RADS score prior to biopsy by Pavlovic, Blaz, Bräutigam, Konstantin, Dartiguenave, Florence, Martel, Paul, Rakauskas, Arnas, Cesson, Valérie, Veit, Markus, Oechslin, Pascal, Gu, Alexander, Hermanns, Thomas, Saba, Karim, Poyet, Cédric, Hötker, Andreas M., Rupp, Niels J., Valerio, Massimo, Derré, Laurent, Eberli, Daniel, Banzola, Irina

“…Prostate-Specific Antigen (PSA) based screening of prostate cancer (PCa) needs refinement. The aim of this study was the identification of urinary biomarkers…”
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Design of short peptides to block BTLA/HVEM interactions for promoting anticancer T-cell responses by Spodzieja, Marta, Lach, Sławomir, Iwaszkiewicz, Justyna, Cesson, Valérie, Kalejta, Katarzyna, Olive, Daniel, Michielin, Olivier, Speiser, Daniel E, Zoete, Vincent, Derré, Laurent, Rodziewicz-Motowidło, Sylwia

“…Antibody based immune-checkpoint blockade therapy is a major breakthrough in oncology, leading to clinical benefit for cancer patients. Among the growing…”
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Targeting Endothelial Connexin37 Reduces Angiogenesis and Decreases Tumor Growth by Sathiyanadan, Karthik, Alonso, Florian, Domingos-Pereira, Sonia, Santoro, Tania, Hamard, Lauriane, Cesson, Valérie, Meda, Paolo, Nardelli-Haefliger, Denise, Haefliger, Jacques-Antoine

“…Connexin37 (Cx37) and Cx40 form intercellular channels between endothelial cells (EC), which contribute to the regulation of the functions of vessels. We…”
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Identification of Urine Biomarkers to Improve Eligibility for Prostate Biopsy and Detect High-Grade Prostate Cancer by Alijaj, Nagjie, Pavlovic, Blaz, Martel, Paul, Rakauskas, Arnas, Cesson, Valérie, Saba, Karim, Hermanns, Thomas, Oechslin, Pascal, Veit, Markus, Provenzano, Maurizio, Rüschoff, Jan H, Brada, Muriel D, Rupp, Niels J, Poyet, Cédric, Derré, Laurent, Valerio, Massimo, Banzola, Irina, Eberli, Daniel

“…PCa screening is based on the measurements of the serum prostate specific antigen (PSA) to select men with higher risks for tumors and, thus, eligible for…”
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Intravesical Bacillus Calmette Guerin Combined with a Cancer Vaccine Increases Local T-Cell Responses in Non-muscle-Invasive Bladder Cancer Patients by Derré, Laurent, Cesson, Valérie, Lucca, Ilaria, Cerantola, Yannick, Valerio, Massimo, Fritschi, Urs, Vlamopoulos, Yannis, Burruni, Rodolfo, Legris, Anne-Sophie, Dartiguenave, Florence, Gharbi, Dalila, Martin, Virginie, Vaucher, Laurent, Speiser, Daniel E, Romero, Pedro, Jichlinski, Patrice, Nardelli-Haefliger, Denise

“…Treatments with cancer vaccines may be delivered as combination therapies for better efficacy. Addition of intravesical immunostimulation with bacteria…”
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Intravesical Ty21a treatment of non-muscle invasive bladder cancer induces immune responses that correlate with safety and may be associated to therapy potential by Derré, Laurent, Lucca, Ilaria, Cesson, Valérie, Bohner, Perrine, Crettenand, Francois, Rodrigues-Dias, Sonia-Cristina, Dartiguenave, Florence, Masnada, Audrey, Teixeira-Pereira, Carla, Benmerzoug, Sulayman, Chevalier, Mathieu F, Domingos-Pereira, Sonia, Nguyen, Sylvain, Polak, Lenka, Schneider, Anna K, Jichlinski, Patrice, Roth, Beat, Nardelli-Haefliger, Denise

“…BackgroundStandard of care treatment of non-muscle invasive bladder cancer (NMIBC) with intravesical Bacillus Calmette Guérin (BCG) is associated with side…”
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Siglec-7 May Limit Natural Killer Cell–mediated Antitumor responses in Bladder Cancer Patients by Benmerzoug, Sulayman, Chevalier, Mathieu F., Villier, Laura, Nguyen, Sylvain, Cesson, Valérie, Schneider, Anna K., Dartiguenave, Florence, Rodrigues-Dias, Sonia-Christina, Lucca, Ilaria, Jichlinski, Patrice, Roth, Beat, Nardelli-Haefliger, Denise, Derré, Laurent

“…Aberrant glycosylation actively contributes to tumor progression and is a key hallmark of cancer. Most of the glycan moieties expressed on the surface of…”
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Preclinical efficacy and safety of the Ty21a vaccine strain for intravesical immunotherapy of non-muscle-invasive bladder cancer by Domingos-Pereira, Sonia, Cesson, Valérie, Chevalier, Mathieu F., Derré, Laurent, Jichlinski, Patrice, Nardelli-Haefliger, Denise

“…Intravesical Bacillus-Calmette-Guérin (BCG) immunotherapy can reduce recurrence/progression of non-muscle-invasive bladder cancer (NMIBC), although significant…”
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Phenotype and Reactivity of Lymphocytes Expanded from Benign Prostate Hyperplasic Tissues and Prostate Cancer by Ahmed, Ritaparna, Lozano, Leyder Elena, Anastasio, Amandine, Lofek, Sebastien, Mastelic-Gavillet, Beatris, Navarro Rodrigo, Blanca, Nguyen, Sylvain, Dartiguenave, Florence, Rodrigues-Dias, Sonia-Cristina, Cesson, Valérie, Valério, Massimo, Roth, Beat, Kandalaft, Lana Elias, Redchenko, Irina, Hill, Adrian Vivian Sinton, Harari, Alexandre, Romero, Pedro, Derré, Laurent, Viganó, Selena

“…Benign prostate hyperplasia (BPH) is a frequent condition in aging men, which affects life quality, causing principally lower urinary tract symptoms…”
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Intravesical Ty21a Treatment of Non–muscle-invasive Bladder Cancer Shows a Good Safety Profile by Lucca, Ilaria, Derré, Laurent, Cesson, Valérie, Bohner, Perrine, Crettenand, François, Rodrigues-Dias, Sonia, Dartiguenave, Florence, Masnada, Audrey, Texeira-Pereira, Carla, Benmerzoug, Sulayman, Chevalier, Mathieu, Domingos-Pereira, Sonia, Nguyen, Sylvain, Polak, Lenka, Schneider, Anna, Roth, Beat, Jichlinski, Patrice, Nardelli-Haefliger, Denise

“…Standard-of-care immunotherapy for non–muscle-invasive bladder cancer (NMIBC) with intravesical Bacillus Calmettte-Guérin (BCG) is associated with adverse…”
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Vδ2 T cells are associated with favorable clinical outcomes in patients with bladder cancer and their tumor reactivity can be boosted by BCG and zoledronate treatments by Nguyen, Sylvain, Chevalier, Mathieu F, Benmerzoug, Sulayman, Cesson, Valérie, Schneider, Anna K, Rodrigues-Dias, Sonia-Cristina, Dartiguenave, Florence, Lucca, Ilaria, Jichlinski, Patrice, Roth, Beat, Nardelli-Haefliger, Denise, Derré, Laurent

“…Background Bladder cancer is an important public health concern due to its prevalence, high risk of recurrence and associated cost of management. Although BCG…”
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Siglec-6 as a New Potential Immune Checkpoint for Bladder Cancer Patients by Benmerzoug, Sulayman, Chevalier, Mathieu F., Verardo, Maëlle, Nguyen, Sylvain, Cesson, Valérie, Schneider, Anna K., Dartiguenave, Florence, Rodrigues-Dias, Sonia-Christina, Lucca, Ilaria, Jichlinski, Patrice, Roth, Beat, Nardelli-Haefliger, Denise, Derré, Laurent

“…Among the growing family of inhibitory receptors regulating immunity, sialic acid–binding immunoglobulin domain–containing lectins (Siglecs) have recently…”
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Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice by Stirnemann, Kathrin, Romero, Jackeline F, Baldi, Lucia, Robert, Bruno, Cesson, Valérie, Besra, Gurdyal S, Zauderer, Maurice, Wurm, Florian, Corradin, Giampietro, Mach, Jean-Pierre, Macdonald, H Robson, Donda, Alena

“…Invariant NKT (iNKT) cells are potent activators of DCs, NK cells, and T cells, and their antitumor activity has been well demonstrated. A single injection of…”
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Intramuscular Immunization Induces Antigen-specific Antibodies in Urine by Derré, Laurent, Lucca, Ilaria, Cesson, Valérie, Valerio, Massimo, Cerantola, Yannick, Burruni, Rodolfo, Fritschi, Urs, Gharbi, Dalila, Bobst, Martine, Legris, Anne-Sophie, Dartiguenave, Florence, Jichlinski, Patrice, Nardelli-Haefliger, Denise

“…Towards the development of vaccines against urinary tract infections (UTI), we determined the ability of intramuscular (i.m.) immunization to result in…”
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MAGE-A3 and MAGE-A4 specific CD4+ T cells in head and neck cancer patients: detection of naturally acquired responses and identification of new epitopes by Cesson, Valérie, Rivals, Jean-Paul, Escher, Anette, Piotet, Elsa, Thielemans, Kris, Posevitz, Vilmos, Dojcinovic, Danijel, Monnier, Philippe, Speiser, Daniel, Bron, Luc, Romero, Pedro

“…Frequent expression of cancer testis antigens (CTA) has been consistently observed in head and neck squamous cell carcinomas (HNSCC). For instance, in 52 HNSCC…”
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MHC Class I–Related Chain A Conjugated to Antitumor Antibodies Can Sensitize Tumor Cells to Specific Lysis by Natural Killer Cells by GERMAIN, Claire, LARBOURET, Christel, CESSON, Valérie, DONDA, Alena, HELD, Werner, MACH, Jean-Pierre, PELEGRIN, André, ROBERT, Bruno

“…Purpose: As a first step for the development of a new cancer immunotherapy strategy, we evaluated whether antibody-mediated coating by MHC class I–related…”
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ILC2-modulated T cell-to-MDSC balance is associated with bladder cancer recurrence by Chevalier, Mathieu F, Trabanelli, Sara, Racle, Julien, Salomé, Bérengère, Cesson, Valérie, Gharbi, Dalila, Bohner, Perrine, Domingos-Pereira, Sonia, Dartiguenave, Florence, Fritschi, Anne-Sophie, Speiser, Daniel E, Rentsch, Cyrill A, Gfeller, David, Jichlinski, Patrice, Nardelli-Haefliger, Denise, Jandus, Camilla, Derré, Laurent

“…Non-muscle-invasive bladder cancer (NMIBC) is a highly recurrent tumor despite intravesical immunotherapy instillation with the bacillus Calmette-Guérin (BCG)…”
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Double Positive CD4 + CD8 + T Cells Are Enriched in Urological Cancers and Favor T Helper-2 Polarization by Bohner, Perrine, Chevalier, Mathieu F, Cesson, Valérie, Rodrigues-Dias, Sonia-Christina, Dartiguenave, Florence, Burruni, Rodolfo, Tawadros, Thomas, Valerio, Massimo, Lucca, Ilaria, Nardelli-Haefliger, Denise, Jichlinski, Patrice, Derré, Laurent

“…The immune system plays a central role in cancer development, showing both anti-tumor and pro-tumor activities depending on the immune cell subsets and the…”
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Active antiviral T-lymphocyte response can be redirected against tumor cells by antitumor antibody x MHC/viral peptide conjugates by CESSON, Valérie, STIRNEMANN, Kathrin, ROBERT, Bruno, LUESCHER, Immanuel, FILLERON, Thomas, CORRADIN, Giampietro, MACH, Jean-Pierre, DONDA, Alena

“…To redirect an ongoing antiviral T-cell response against tumor cells in vivo, we evaluated conjugates consisting of antitumor antibody fragments coupled to…”
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Disulfide-Linked Peptides for Blocking BTLA/HVEM Binding by Spodzieja, Marta, Kuncewicz, Katarzyna, Sieradzan, Adam, Karczyńska, Agnieszka, Iwaszkiewicz, Justyna, Cesson, Valérie, Węgrzyn, Katarzyna, Zhukov, Igor, Maszota-Zieleniak, Martyna, Michielin, Olivier, Speiser, Daniel E, Zoete, Vincent, Derré, Laurent, Rodziewicz-Motowidło, Sylwia

“…Immune checkpoints are crucial in the maintenance of antitumor immune responses. The activation or blockade of immune checkpoints is dependent on the…”
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