Search Results - "CESKA, R"
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Treatment of hypertriglyceridemia: a review of current options
Published in Physiological research (01-01-2015)“…Hypertriglyceridemia is an important marker of increased levels of highly atherogenic remnant-like particles. The importance of lowering plasma levels of…”
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Statin Intolerance in Clinical Practice
Published in Current atherosclerosis reports (03-06-2020)“…Purpose of Review In our pilot study, we aimed to determine how many patients with the statin intolerance history referred to the specialized center for the…”
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Biomarkers of cardiometabolic risk in obese/overweight children: effect of lifestyle intervention
Published in Physiological research (01-01-2014)“…Obesity is a strong cardiometabolic (CM) risk factor in children. We tested potential CM risk in obese/overweight children and the effect of an intensive…”
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Statin-associated myopathy: from genetic predisposition to clinical management
Published in Physiological research (01-01-2014)“…Statin-associated myopathy (SAM) represents a broad spectrum of disorders from insignificant myalgia to fatal rhabdomyolysis. Its frequency ranges from 1-5 %…”
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FTO and MC4R gene variants determine BMI changes in children after intensive lifestyle intervention
Published in Clinical biochemistry (01-03-2013)“…This study aimed to determine whether there is a relationship between common FTO (rs17817449) and MC4R (rs17782313) gene variants and body mass reduction or…”
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Gene variants at FTO, 9p21, and 2q36.3 are age-independently associated with myocardial infarction in Czech men
Published in Clinica chimica acta (15-02-2016)“…Cardiovascular disease (CVD) is a major cause of morbidity and mortality in developed countries. This study aimed to confirm the effect of common putative…”
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ScreenPro FH: from the Czech MedPed to international collaboration. ScreenPro FH is a participating project of the EAS-FHCS
Published in Physiological research (01-01-2017)“…This article describes the evolution of our understanding of familial hypercholesterolemia (FH) in the Central, Eastern, and Southern Europe (CESE) region, and…”
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Rosiglitazone influences the expression of leukocyte adhesion molecules and CD14 receptor in type 2 diabetes mellitus patients
Published in Physiological research (01-01-2014)“…Diabetes mellitus is associated with increased inflammatory response, which may contribute to atherosclerosis progression. Experimental results demonstrated…”
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SLCO1B1 transporter polymorphism is not associated with risk of myopathy in Czech population
Published in Atherosclerosis (01-08-2014)Get full text
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Effect of APOE genotype on LDL cholesterol levels in FH and FDB patients: Is there sex-specifically protective genotype?
Published in Atherosclerosis (01-09-2016)Get full text
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FH homozygote without cardiovascular disease at the age of 40
Published in Atherosclerosis (01-07-2015)Get full text
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Impact of variants within seven candidate genes on statin treatment efficacy
Published in Physiological research (01-01-2012)“…Statins are the most commonly used drugs in patients with dyslipidemia. Among the patients, a significant inter-individual variability with supposed strong…”
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Strong Association between APOA5 Gene Polymorphisms and Hypertriglyceridaemic Episodes
Published in Folia biologica (01-01-2019)“…Plasma triglyceride (TG) levels represent a significant risk factor of cardiovascular and total mortality. Concentrations of TG in the plasma depend, to a…”
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Fifteen years of active search for patients with familial hypercholesterolemia in the Czech Republic
Published in Atherosclerosis (01-08-2014)Get full text
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15
Therapeutic equivalence of the generic and the reference atorvastatin in patients with increased coronary risk
Published in International angiology (01-08-2011)“…Generic drugs are more and more frequently used instead of originators. However, uncertainty exists with respect to therapeutic equivalence of generic product…”
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Leukocyte and endothelial adhesion molecules in patients with hypercholesterolemia: the effect of atorvastatin treatment
Published in Physiological research (01-01-2008)“…Atherogenesis involves the migration of leukocytes into vascular subendothelial space, a process mediated by endothelial and leukocyte cell adhesion molecules…”
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Efficacy and safety of extended-release niacin/laropiprant plus statin vs. doubling the dose of statin in patients with primary hypercholesterolaemia or mixed dyslipidaemia
Published in International journal of clinical practice (Esher) (01-05-2010)“…Co-administration of niacin with statin offers the potential for additional lipid management and cardiovascular risk reduction. However, niacin is…”
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Lower wall shear rate of the common carotid artery in treated type 2 diabetes mellitus with metabolic syndrome
Published in Physiological research (01-01-2009)“…Arterial sites with low wall shear stress (WSS) are more prone to the development of atherosclerotic plaques, as was observed in carotid arteries in subjects…”
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APOA5 haplotypes determine triglyceride decrease after lifestyle induced weight loss in children
Published in Nutrition, metabolism, and cardiovascular diseases (01-09-2012)Get full text
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