Search Results - "CERNA, TEREZA"
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The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells
Published in International journal of molecular sciences (05-01-2018)“…Neuroblastoma (NBL) originates from undifferentiated cells of the sympathetic nervous system. Chemotherapy is judged to be suitable for successful treatment of…”
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Screening for 32 per- and polyfluoroalkyl substances (PFAS) including GenX in sludges from 43 WWTPs located in the Czech Republic - Evaluation of potential accumulation in vegetables after application of biosolids
Published in Chemosphere (Oxford) (01-12-2020)“…Highly persistent, toxic and bioaccumulative per - and polyfluoroalkyl substances (PFAS) represents a serious problem for the environment and their…”
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Evaluation of estrogenic and antiestrogenic activity in sludge and explanation of individual compound contributions
Published in Journal of hazardous materials (05-02-2022)“…Mixture toxicity, including agonistic and antagonistic effects, is an unrevealed environmental problem. Estrogenic endocrine disruptors are known to cause…”
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Polycyclic aromatic hydrocarbon accumulation in aged and unaged polyurethane microplastics in contaminated soil
Published in The Science of the total environment (20-05-2021)“…The interaction of microplastics (MPs) and common environmental organic pollutants has been a frequently discussed topic in recent years. Although the…”
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Bioactivity assessment, micropollutant and nutrient removal ability of Tetradesmus obliquus cultivated outdoors in centrate from urban wastewater
Published in Journal of applied phycology (01-12-2022)“…Nutrient and micropollutant removal, and bioactivity were studied in cultures of the green microalga Tetradesmus obliquus MACC-677 grown in centrate from…”
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Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells
Published in Toxicology (Amsterdam) (01-05-2019)“…Although ellipticine (Elli) is an efficient anticancer agent, it exerts several adverse effects. One approach to decrease the adverse effects of drugs is their…”
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The antimicrobial action of histones in the reproductive tract of cow
Published in Biochemical and biophysical research communications (17-01-2014)“…•Comparison of antimicrobial properties of fluids from reproductive tract of cow.•Only compounds smaller than 30,000 contribute to these antimicrobial…”
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Site-Directed Conjugation of Antibodies to Apoferritin Nanocarrier for Targeted Drug Delivery to Prostate Cancer Cells
Published in ACS applied materials & interfaces (15-06-2016)“…Herein, we describe a novel approach for targeting of ubiquitous protein apoferritin (APO)-encapsulating doxorubicin (DOX) to prostate cancer using antibodies…”
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Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells
Published in International journal of oncology (01-09-2015)“…Neuroblastoma is the most common cancer in infants and the fourth most common cancer in children. Aggressive cell growth and chemoresistance are notorious…”
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Effectiveness of human cytochrome P450 3A4 present in liposomal and microsomal nanoparticles in formation of covalent DNA adducts by ellipticine
Published in Neuro-endocrinology letters (18-12-2016)“…Ellipticine is an anticancer agent that functions through multiple mechanisms participating in cell cycle arrest and initiation of apoptosis. This drug forms…”
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Hydrogel implants for transscleral drug delivery for retinoblastoma treatment
Published in Materials Science & Engineering C (01-10-2019)“…Retinoblastoma (Rb) is the most common primary malignant intraocular tumor in children which develops from the retinal stem cells. Systemic chemotherapy is the…”
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Poly(d,l-lactide)/polyethylene glycol micro/nanofiber mats as paclitaxel-eluting carriers: preparation and characterization of fibers, in vitro drug release, antiangiogenic activity and tumor recurrence prevention
Published in Materials Science & Engineering C (01-05-2019)“…Poly(d,l-lactide)/polyethylene glycol (PLA/PEG) micro/nanofibers loaded with paclitaxel (PTX, 10 wt%) were prepared by needless electrospinning technology,…”
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Construction of an apoferritin nanocarrier with encapsulated ellipticine and examination of its properties
Published in Toxicology letters (20-10-2017)Get full text
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