Search Results - "CERI, M"

Multimillijoule coherent terahertz bursts from picosecond laser-irradiated metal foils by Liao, Guoqian, Li, Yutong, Liu, Hao, Scott, Graeme G., Neely, David, Zhang, Yihang, Zhu, Baojun, Zhang, Zhe, Armstrong, Chris, Zemaityte, Egle, Bradford, Philip, Huggard, Peter G., Rusby, Dean R., McKenna, Paul, Brenner, Ceri M., Woolsey, Nigel C., Wang, Weimin, Sheng, Zhengming, Zhang, Jie

“…Ultrahigh-power terahertz (THz) radiation sources are essential for many applications, for example, THz-wave-based compact accelerators and THz control over…”
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Do the Big-Five Personality Traits Predict Empathic Listening and Assertive Communication? by Sims, Ceri M.

“…As personality traits can influence important social outcomes, the current research investigated whether the Big-Five had predictive influences on…”
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Towards Terawatt-Scale Spectrally Tunable Terahertz Pulses via Relativistic Laser-Foil Interactions by Liao, Guo-Qian, Liu, Hao, Scott, Graeme G., Zhang, Yi-Hang, Zhu, Bao-Jun, Zhang, Zhe, Li, Yu-Tong, Armstrong, Chris, Zemaityte, Egle, Bradford, Philip, Rusby, Dean R., Neely, David, Huggard, Peter G., McKenna, Paul, Brenner, Ceri M., Woolsey, Nigel C., Wang, Wei-Min, Sheng, Zheng-Ming, Zhang, Jie

“…An ever-increasing number of strong-field applications, such as ultrafast coherent control over matter and light, require driver light pulses that are both…”
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Direct Inhibitory Effect of the PDE4 Inhibitor Roflumilast on Neutrophil Migration in Chronic Obstructive Pulmonary Disease by Dunne, Amy E, Kawamatawong, Theerasuk, Fenwick, Peter S, Davies, Ceri M, Tullett, Hannah, Barnes, Peter J, Donnelly, Louise E

“…Neutrophilic inflammation is characteristic of chronic obstructive pulmonary disease (COPD); yet, there are no effective antiinflammatory therapies. The PDE4…”
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Bim and the Pro-Survival Bcl-2 Proteins: Opposites Attract, ERK Repels by Ewings, Katherine E., Wiggins, Ceri M., Cook, Simon J.

“…Bim (Bcl-2-interacting mediator of cell death) is a BH3-only protein (BOP), a pro-apoptotic member of the Bcl-2 protein family. The Bim mRNA undergoes…”
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An aptamer-mediated base editing platform for simultaneous knockin and multiple gene knockout for allogeneic CAR-T cells generation by Porreca, Immacolata, Blassberg, Robert, Harbottle, Jennifer, Joubert, Bronwyn, Mielczarek, Olga, Stombaugh, Jesse, Hemphill, Kevin, Sumner, Jonathan, Pazeraitis, Deividas, Touza, Julia Liz, Francescatto, Margherita, Firth, Mike, Selmi, Tommaso, Collantes, Juan Carlos, Strezoska, Zaklina, Taylor, Benjamin, Jin, Shengkan, Wiggins, Ceri M, van Brabant Smith, Anja, Lambourne, John J

“…Gene editing technologies hold promise for enabling the next generation of adoptive cellular therapies. In conventional gene editing platforms that rely on…”
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ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL by Ewings, Katherine E, Hadfield-Moorhouse, Kathryn, Wiggins, Ceri M, Wickenden, Julie A, Balmanno, Kathryn, Gilley, Rebecca, Degenhardt, Kurt, White, Eileen, Cook, Simon J

“…The proapoptotic protein Bim is expressed de novo following withdrawal of serum survival factors. Here, we show that Bim−/− fibroblasts and epithelial cells…”
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A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds by Cairney, Claire J, Godwin, Lauren S, Bilsland, Alan E, Burns, Sharon, Stevenson, Katrina H, McGarry, Lynn, Revie, John, Moore, Jon D, Wiggins, Ceri M, Collinson, Rebecca S, Mudd, Clare, Tsonou, Elpida, Sadaie, Mahito, Bennett, Dorothy C, Narita, Masashi, Torrance, Christopher J, Keith, W Nicol

“…Senescence is a universal barrier to immortalisation and tumorigenesis. As such, interest in the use of senescence-induction in a therapeutic context has been…”
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A Flexible Enclosure to Protect Respiratory Therapists During Aerosol-Generating Procedures by Smith, Cameron R, Gravenstein, Nikolaus, LeMaster, Thomas E, Borde, Ceri M, Fahy, Brenda G

“…Exposure of respiratory therapists (RTs) during aerosol-generating procedures such as endotracheal intubation is an occupational hazard. Depending on the…”
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Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics by Gillings, Annette S, Balmanno, Kathryn, Wiggins, Ceri M, Johnson, Mark, Cook, Simon J

“…The BCL-2 homology domain 3 (BH3)-only protein, B-cell lymphoma 2 interacting mediator of cell death (BIM) is a potent pro-apoptotic protein belonging to the…”
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BIMEL, an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation by Wiggins, Ceri M, Tsvetkov, Peter, Johnson, Mark, Joyce, Claire L, Lamb, Christopher A, Bryant, Nia J, Komander, David, Shaul, Yosef, Cook, Simon J

“…BIM-extra long (BIMEL), a pro-apoptotic BH3-only protein and part of the BCL-2 family, is degraded by the proteasome following activation of the ERK1/2…”
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Pre-clinical use of isogenic cell lines and tumours in vitro and in vivo for predictive biomarker discovery; impact of KRAS and PI3KCA mutation status on MEK inhibitor activity is model dependent by Haagensen, Emma J, Thomas, Huw D, Mudd, Clare, Tsonou, Elpida, Wiggins, Ceri M, Maxwell, Ross J, Moore, Jonathan D, Newell, David R

“…Abstract Studies to identify predictive biomarkers can be carried out in isogenic cancer cell lines, which enable interrogation of the effect of a specific…”
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The Role of Ethics and Social Responsibility in Organizational Success: A Spanish Perspective by Vitell, Scott John, Ramos, Encarnación, Nishihara, Ceri M.

“…Ethics has assumed a dominant position in the current economic debate, and this study focuses on ethics as a legitimate underpinning to good business decision…”
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Evaluating laser-driven Bremsstrahlung radiation sources for imaging and analysis of nuclear waste packages by Jones, Christopher P., Brenner, Ceri M., Stitt, Camilla A., Armstrong, Chris, Rusby, Dean R., Mirfayzi, Seyed R., Wilson, Lucy A., Alejo, Aarón, Ahmed, Hamad, Allott, Ric, Butler, Nicholas M.H., Clarke, Robert J., Haddock, David, Hernandez-Gomez, Cristina, Higginson, Adam, Murphy, Christopher, Notley, Margaret, Paraskevoulakos, Charilaos, Jowsey, John, McKenna, Paul, Neely, David, Kar, Satya, Scott, Thomas B.

“…•X-ray generation was achieved via laser interaction with a tantalum thin foil target.•Picosecond X-ray pulse from a sub-mm spot generated high resolution…”
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Pregnancy after renal transplantation by Ozban, M, Ozban, A S, Birsen, O, Ceri, M, Aydin, H C

“…A well-functioning renal transplant usually reverses ESRD-related infertility and allows the reproductive function to improve. In this study, we wanted to…”
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Development and Characterization of a Modular CRISPR and RNA Aptamer Mediated Base Editing System by Collantes, Juan Carlos, Tan, Victor M, Xu, Huiting, Ruiz-Urigüen, Melany, Alasadi, Amer, Guo, Jingjing, Tao, Hanlin, Su, Chi, Tyc, Katarzyna M, Selmi, Tommaso, Lambourne, John J, Harbottle, Jennifer A, Stombaugh, Jesse, Xing, Jinchuan, Wiggins, Ceri M, Jin, Shengkan

“…Conventional CRISPR approaches for precision genome editing rely on the introduction of DNA double-strand breaks (DSB) and activation of homology-directed…”
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Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM by Wiggins, Ceri M., Johnson, Mark, Cook, Simon J.

“…The pro-apoptotic protein BIM EL is phosphorylated by ERK1/2 and this targets the protein for poly-ubiquitination and degradation by the proteasome as a…”
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c-Cbl is not required for ERK1/2-dependent degradation of BimEL by Wiggins, Ceri M., Band, Hamid, Cook, Simon J.

“…BimEL the most abundant Bim splice variant, is subject to ERK1/2-catalysed phosphorylation, which targets it for ubiquitination and proteasome-dependent…”
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Accidental Placement of a Peritoneal Dialysis Catheter in the Retzius Space: Two Case Reports by KURULTAK, I, KINALP, C, CERI, M, SAYIN, B, SAGLAM, M, EVRENKAYA, T. R

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The use of strategic deception in relationships by Patwardhan, Abhijit, Noble, Stephanie M, Nishihara, Ceri M

“…Purpose - The primary purpose of this research is to explore the use of strategic deception as adopted by call centers endeavoring to establish relationships…”
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