Search Results - "CEREGHINO, J. J"

Heterologous protein expression in the methylotrophic yeast Pichia pastoris by Cereghino, Joan Lin, Cregg, James M.

“…During the past 15 years, the methylotrophic yeast Pichia pastoris has developed into a highly successful system for the production of a variety of…”
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Levetiracetam for partial seizures : Results of a double-blind, randomized clinical trial by CEREGHINO, J. J, BITON, V, ABOU-KHALIL, B, DREIFUSS, F, GAUER, L. J, LEPPIK, I

“…To evaluate the efficacy and safety of 500 mg bid and 1500 mg bid levetiracetam as adjunctive therapy for refractory partial seizures in a double-blind,…”
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Identification and treatment of acute repetitive seizures in children and adults by Cereghino, James J

“…Acute repetitive seizures are a predictable component of a patient's seizure disorder, historically distinct from the patient's other epileptic seizures in…”
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The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene by Marcusson, E G, Horazdovsky, B F, Cereghino, J L, Gharakhanian, E, Emr, S D

“…The S. cerevisiae VPS10 (vacuolar protein sorting) gene encodes a type I transmembrane protein of 1577 amino acids required for the sorting of the soluble…”
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Effect of Levetiracetam on Epilepsy‐Related Quality of Life by Cramer, Joyce A., Arrigo, Celestina, Hammée, Geneviève, Gauer, Laura J., Cereghino, James J.

“…Purpose: To evaluate the short‐term effect of levetiracetam (LEV; UCB L059) as add‐on therapy on health‐related quality of life in the treatment of refractory…”
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Recombinant protein expression in Pichia pastoris by CREGG, James M, CEREGHINO, Joan Lin, JIANYING SHI, HIGGINS, David R

“…The methylotrophic yeast Pichia pastoris is now one of the standard tools used in molecular biology for the generation of recombinant protein. P. pastoris has…”
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Treating repetitive seizures with a rectal diazepam formulation : A randomized study by CEREGHINO, J. J, MITCHELL, W. G, MURPHY, J, KRIEL, R. L, ROSENFELD, W. E, TREVATHAN, E

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An Open‐Label Study of Repeated Use of Diazepam Rectal Gel (Diastat) for Episodes of Acute Breakthrough Seizures and Clusters: Safety, Efficacy, and Tolerance by Mitchell, Wendy G., Conry, J. A., Crumrine, P. K., Kriel, R. L., Cereghino, J. J., Groves, L., Rosenfeld, W. E.

“…Purpose: To assess safety of diazepam rectal gel (DZPRG) for control of acute seizures in epilepsy patients and to evaluate tolerance with repeated use of…”
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The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization by Cereghino, J L, Marcusson, E G, Emr, S D

“…VPS10 of Saccharomyces cerevisiae encodes a type I transmembrane receptor protein required for the sorting of the soluble vacuolar hydrolase carboxypeptidase Y…”
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Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products by Seaman, M.N.J. (University of California-San Diego, La Jolla, CA.), Marcusson, E.G, Cereghino, J.L, Emr, S.D

“…Mutations in the S. cerevisiae VPS29 and VPS30 genes lead to a selective protein sorting defect in which the vacuolar protein carboxypeptidase Y (CPY) is…”
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Felbamate for partial seizures : results of a controlled clinical trial by LEPPIK, I. E, DREIFUSS, F. E, COOPER, G, SAHLROOT, J. T, SHERIDAN, P, ASHWORTH, M, LEE, S. I, SIERZANT, T. L, PLEDGER, G. W, GRAVES, N. M, SANTILLI, N, DRURY, I, TSAY, J. Y, JACOBS, M. P, BERTRAM, E, CEREGHINO, J. J

“…Felbamate (2-phenyl-1,3-propanediol dicarbamate) has a favorable preclinical profile in animal models of epilepsy. We present the results of a double-blind,…”
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The major advances in epilepsy in the 20th century and what we can expect (hope for) in the future by Cereghino, James J.

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1,4-benzoquinone reductase from Phanerochaete chrysosporium: cDNA cloning and regulation of expression by Akileswaran, L, Brock, B.J, Cereghino, J.L, Gold, M.H

“…A cDNA clone encoding a quinone reductase (QR) from the white rot basidiomycete Phanerochaete chrysosporium was isolated and sequenced. The cDNA consisted of…”
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Rectal diazepam gel for treatment of acute repetitive seizures by Kriel, Robert L., Cloyd, James C., Pellock, John M., Mitchell, Wendy G., Cereghino, James J., Rosman, N.Paul

“…The purpose of these investigations was to determine from combined data the response to rectal diazepam (DZP) gel (Diastat [Athena Neurosciences, South San…”
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Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures by MIRZA, W. U, RAK, I. W, THADANI, V. M, CEREGHINO, J. J, GARNETT, W. R, BROWN, L. M, ZHANG, Y, BELENDIUK, G. W

“…We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with…”
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New selectable marker/auxotrophic host strain combinations for molecular genetic manipulation of Pichia pastoris by Lin Cereghino, G P, Lin Cereghino, J, Sunga, A J, Johnson, M A, Lim, M, Gleeson, M A, Cregg, J M

“…We describe the isolation and characterization of three new biosynthetic genes-ARG4, ADE1, and URA3-from the methylotrophic yeast Pichia pastoris. The…”
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Expression of foreign genes in the yeast Pichia pastoris by Lin Cereghino, G P, Sunga, A J, Lin Cereghino, J, Cregg, J M

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Pichia pastoris Pex14p, a phosphorylated peroxisomal membrane protein, is part of a PTS–receptor docking complex and interacts with many peroxins by Johnson, Monique A., Snyder, William B., Lin Cereghino, Joan, Veenhuis, Marten, Subramani, Suresh, Cregg, James M.

“…The peroxisomal protein import machinery plays a central role in the assembly of this organelle in all eukaryotes. Genes encoding components of this machinery,…”
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Antiepileptic Drug Development Program by Porter, R J, Cereghino, J J, Gladding, G D, Hessie, B J, Kupferberg, H J, Scoville, B, White, B G

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Essentiality of the three carboxyl-terminal amino acids of the plasmid RK2 replication initiation protein TrfA for DNA binding and replication activity in gram-negative bacteria by Cereghino, J L, Helinski, D R

“…In a previous study of mutations in trfA, the gene encoding the replication initiation protein of the broad host-range plasmid RK2, a carboxyl-terminal…”
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