Search Results - "CAVE, H"

IKZF1 deletion is an independent prognostic marker in childhood B-cell precursor acute lymphoblastic leukemia, and distinguishes patients benefiting from pulses during maintenance therapy: results of the EORTC Children's Leukemia Group study 58951 by Clappier, E, Grardel, N, Bakkus, M, Rapion, J, De Moerloose, B, Kastner, P, Caye, A, Vivent, J, Costa, V, Ferster, A, Lutz, P, Mazingue, F, Millot, F, Plantaz, D, Plat, G, Plouvier, E, Poirée, M, Sirvent, N, Uyttebroeck, A, Yakouben, K, Girard, S, Dastugue, N, Suciu, S, Benoit, Y, Bertrand, Y, Cavé, H

“…The added value of IKZF1 gene deletion ( IKZF1 del ) as a stratifying criterion in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is still debated. We…”
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An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions by Clappier, E, Auclerc, M-F, Rapion, J, Bakkus, M, Caye, A, Khemiri, A, Giroux, C, Hernandez, L, Kabongo, E, Savola, S, Leblanc, T, Yakouben, K, Plat, G, Costa, V, Ferster, A, Girard, S, Fenneteau, O, Cayuela, J-M, Sigaux, F, Dastugue, N, Suciu, S, Benoit, Y, Bertrand, Y, Soulier, J, Cavé, H

“…Oncogenic subtypes in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) are used for risk stratification. However, a significant number of…”
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Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia by Ellinghaus, E, Stanulla, M, Richter, G, Ellinghaus, D, te Kronnie, G, Cario, G, Cazzaniga, G, Horstmann, M, Panzer Grümayer, R, Cavé, H, Trka, J, Cinek, O, Teigler-Schlegel, A, ElSharawy, A, Häsler, R, Nebel, A, Meissner, B, Bartram, T, Lescai, F, Franceschi, C, Giordan, M, Nürnberg, P, Heinzow, B, Zimmermann, M, Schreiber, S, Schrappe, M, Franke, A

“…Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ALL is believed to be multifactorial and likely to involve…”
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Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph + ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1 by Pfeifer, H., Cazzaniga, G., van der Velden, V. H. J., Cayuela, J. M., Schäfer, B., Spinelli, O., Akiki, S., Avigad, S., Bendit, I., Borg, K., Cavé, H., Elia, L., Reshmi, S. C., Gerrard, G., Hayette, S., Hermanson, M., Juh, A., Jurcek, T., Chillón, M. C., Homburg, C., Martinelli, G., Kairisto, V., Lange, T., Lion, T., Mueller, M. C., Pane, F., Rai, L., Damm-Welk, C., Sacha, T., Schnittger, S., Touloumenidou, T., Valerhaugen, H., Vandenberghe, P., Zuna, J., Serve, H., Herrmann, E., Markovic, S., Dongen, J. J. M. van, Ottmann, O. G.

“…Minimal residual disease (MRD) is a powerful prognostic factor in acute lymphoblastic leukemia (ALL) and is used for patient stratification and treatment…”
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Refinement of IKZF1 status in pediatric Philadelphia-positive acute lymphoblastic leukemia by Lana, T, de Lorenzo, P, Bresolin, S, Bronzini, I, den Boer, M L, Cavé, H, Froňková, E, Stanulla, M, Zaliova, M, Harrison, C J, de Groot, H, Valsecchi, M G, Biondi, A, Basso, G, Cazzaniga, G, te Kronnie, G

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Flow cytometry and IG/TCR quantitative PCR for minimal residual disease quantitation in acute lymphoblastic leukemia: a French multicenter prospective study on behalf of the FRALLE, EORTC and GRAALL by Garand, R, Beldjord, K, Cavé, H, Fossat, C, Arnoux, I, Asnafi, V, Bertrand, Y, Boulland, M-L, Brouzes, C, Clappier, E, Delabesse, E, Fest, T, Garnache-Ottou, F, Huguet, F, Jacob, M-C, Kuhlein, E, Marty-Grès, S, Plesa, A, Robillard, N, Roussel, M, Tkaczuk, J, Dombret, H, Macintyre, E, Ifrah, N, Béné, M C, Baruchel, A

“…Minimal residual disease (MRD) quantification is widely used for therapeutic stratification in pediatric acute lymphoblastic leukemia (ALL). A robust,…”
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Dermatological manifestations in Noonan syndrome: a prospective multicentric study of 129 patients positive for mutation by Bessis, D., Miquel, J., Bourrat, E., Chiaverini, C., Morice‐Picard, F., Abadie, C., Manna, F., Baumann, C., Best, M., Blanchet, P., Bursztejn, A.‐C., Capri, Y., Coubes, C., Giuliano, F., Guillaumont, S., Hadj‐Rabia, S., Jacquemont, M.‐L., Jeandel, C., Lacombe, D., Mallet, S., Mazereeuw‐Hautier, J., Molinari, N., Pallure, V., Pernet, C., Philip, N., Pinson, L., Sarda, P., Sigaudy, S., Vial, Y., Willems, M., Geneviève, D., Verloes, A., Cavé, H.

“…Summary Background Data on dermatological manifestations of Noonan syndrome (NS) remain heterogeneous and are based on limited dermatological expertise…”
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Activating Mutations in the ABCC8 Gene in Neonatal Diabetes Mellitus by Babenko, Andrey P, Polak, Michel, Cavé, Hélène, Busiah, Kanetee, Czernichow, Paul, Scharfmann, Raphael, Bryan, Joseph, Aguilar-Bryan, Lydia, Vaxillaire, Martine, Froguel, Philippe

“…In this study, mutations in the gene encoding the sulfonylurea receptor, a component of the beta-cell ATP-sensitive potassium channel, are described in infants…”
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Orthotrichum cupulatum Hoffm. ex Brid. var. lithophilum, a new variety of epilithic bristle moss from Tasmania by Plášek, Vítězslav, Sawicki, Jakub, Seppelt, Rodney D., Cave, Lynette H.

“…Orthotrichum cupulatum var. lithophilum is described as a new variety from Tasmania, Australia. The species is primarily characterized by its exserted capsule…”
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Germline mutations of the CBL gene define a new genetic syndrome with predisposition to juvenile myelomonocytic leukaemia by Pérez, B, Mechinaud, F, Galambrun, C, Ben Romdhane, N, Isidor, B, Philip, N, Derain-Court, J, Cassinat, B, Lachenaud, J, Kaltenbach, S, Salmon, A, Désirée, C, Pereira, S, Menot, M L, Royer, N, Fenneteau, O, Baruchel, A, Chomienne, C, Verloes, A, Cavé, H

“…CBL missense mutations have recently been associated with juvenile myelomonocytic leukaemia (JMML), an aggressive myeloproliferative and myelodysplastic…”
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PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study by Familiades, J, Bousquet, M, Lafage-Pochitaloff, M, Béné, M-C, Beldjord, K, De Vos, J, Dastugue, N, Coyaud, E, Struski, S, Quelen, C, Prade-Houdellier, N, Dobbelstein, S, Cayuela, J-M, Soulier, J, Grardel, N, Preudhomme, C, Cavé, H, Blanchet, O, Lhéritier, V, Delannoy, A, Chalandon, Y, Ifrah, N, Pigneux, A, Brousset, P, Macintyre, E A, Huguet, F, Dombret, H, Broccardo, C, Delabesse, É

“…Adult and child B-cell progenitor acute lymphoblastic leukemia (BCP-ALL) differ in terms of incidence and prognosis. These disparities are mainly due to the…”
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Analysis of minimal residual disease by Ig TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data by VAN DER VELDEN, V. H. J, CAZZANIGA, G, CAYUELA, J. M, TRKA, J, ECKERT, C, FORONI, L, ZUR STADT, U, BELDJORD, K, RAFF, T, VAN DER SCHOOT, C. E, VAN DONGEN, J. J. M, SCHRAUDER, A, HANCOCK, J, BADER, P, PANZER-GRUMAYER, E. R, FLOHR, T, SUTTON, R, CAVE, H, MADSEN, H. O

“…Most modern treatment protocols for acute lymphoblastic leukaemia (ALL) include the analysis of minimal residual disease (MRD). To ensure comparable MRD…”
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Differential impact of drugs on the outcome of ETV6-RUNX1 positive childhood B-cell precursor acute lymphoblastic leukaemia: results of the EORTC CLG 58881 and 58951 trials by Piette, C, Suciu, S, Clappier, E, Bertrand, Y, Drunat, S, Girard, S, Yakouben, K, Plat, G, Dastugue, N, Mazingue, F, Grardel, N, van Roy, N, Uyttebroeck, A, Costa, V, Minckes, O, Sirvent, N, Simon, P, Lutz, P, Ferster, A, Pluchart, C, Poirée, M, Freycon, C, Dresse, M-F, Millot, F, Chantrain, C, van der Werff ten Bosch, J, Norga, K, Gilotay, C, Rohrlich, P-S, Benoit, Y, Cavé, H

“…In childhood B-cell precursor acute lymphoblastic leukaemias (BCP-ALL), the presence of an ETV6-RUNX1 fusion transcript defines one of the most prevalent…”
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Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia by Caye, Aurélie, Beldjord, Kheïra, Mass-Malo, Kelly, Drunat, Séverine, Soulier, Jean, Gandemer, Virginie, Baruchel, André, Bertrand, Yves, Cavé, Hélène, Clappier, Emmanuelle

“…Deletion of the Ikaros (IKZF1) gene is an oncogenic lesion frequently associated with BCR-ABL1-positive acute lymphoblastic leukemias. It is also found in a…”
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Environmentally responsible management in international business: a literature review by Cave, Adam H

“…Purpose – This paper sets out to identify and categorize existing academic literature using the CSA/FSA matrix as it relates to environmentally responsible…”
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Kir6.2 Mutations Are a Common Cause of Permanent Neonatal Diabetes in a Large Cohort of French Patients by VAXILLAIRE, Martine, POPULAIRE, Céline, BUSIAH, Kanetee, CAVE, Hélène, GLOYN, Anna L, HATTERSLEY, Andrew T, CZERNICHOW, Paul, FROGUEL, Philippe, POLAK, Michel

“…Kir6.2 Mutations Are a Common Cause of Permanent Neonatal Diabetes in a Large Cohort of French Patients Martine Vaxillaire 1 , Céline Populaire 1 , Kanetee…”
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An improved Quiet Direct Simulation method for Eulerian fluids using a second-order scheme by Smith, M.R., Cave, H.M., Wu, J.-S., Jermy, M.C., Chen, Y.-S.

“…In this paper, a second-order scheme for the Quiet Direct Simulation (QDS) of Eulerian fluids is proposed. The QDS method replaces the random sampling method…”
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Implementation of a transient adaptive sub-cell module for the parallel-DSMC code using unstructured grids by Su, C.C., Tseng, K.C., Cave, H.M., Wu, J.S., Lian, Y.Y., Kuo, T.C., Jermy, M.C.

“…A method of transient adaptive sub-cells (TAS) suitable for unstructured grids that is modified from the existing one for the structured grids of DSMC is…”
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Childhood secondary ALL after ALL treatment by ZUNA, J, CAVD, H, BOUTARD, P, SCHRAUDER, A, STERBA, J, MARSCHALEK, R, VAN DONGEN, J. J. M, HRUSAK, O, STARY, J, TRKA, J, ECKERT, C, SZCZEPANSKI, T, MEYER, C, MEJSTRIKOVA, E, FRONKOVA, E, MUZIKOVA, K, CLAPPIER, E, MENDELOVA, D

“…Data on secondary acute lymphoblastic leukaemia (sALL) following ALL treatment are very rare. However, the incidence might be underestimated as sALLs without a…”
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Transient neonatal diabetes mellitus and activating mutation in the KCNJ11 gene in two siblings by Kamoun, T., Chabchoub, I., Ben Ameur, S., Kmiha, S., Aloulou, H., Cave, H., Polak, M., Hachicha, M.

“…Transient neonatal diabetes mellitus is a rare disease usually associated with chromosome 6 abnormalities. Mutations of the genes encoding the potassium…”
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