Search Results - "CAUGHLAN, Ruth E"

Mechanisms Decreasing In Vitro Susceptibility to the LpxC Inhibitor CHIR-090 in the Gram-Negative Pathogen Pseudomonas aeruginosa by CAUGHLAN, Ruth E, JONES, Adriana K, DEAN, Charles R, DELUCIA, Angela M, WOODS, Angela L, LILI XIE, BING MA, BARNES, S. Whitney, WALKER, John R, SPRAGUE, Elizabeth R, XIA YANG

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Author Correction: Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase by Kreamer, Naomi N. K., Chopra, Rajiv, Caughlan, Ruth E., Fabbro, Doriano, Fang, Eric, Gee, Patricia, Hunt, Ian, Li, Min, Leon, Barbara C., Muller, Lionel, Vash, Brian, Woods, Angela L., Stams, Travis, Dean, Charles R., Uehara, Tsuyoshi

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper…”
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Fmt Bypass in Pseudomonas aeruginosa Causes Induction of MexXY Efflux Pump Expression by CAUGHLAN, Ruth E, SRIRAM, Shubha, DAIGLE, Denis M, WOODS, Angela L, BUCO, Jennifer, PETERSON, Ron L, DZINK-FOX, Joann, WALKER, Susan, DEAN, Charles R

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Lipopolysaccharide (LPS) inner-core phosphates are required for complete LPS synthesis and transport to the outer membrane in Pseudomonas aeruginosa PAO1 by Delucia, Angela M, Six, David A, Caughlan, Ruth E, Gee, Patricia, Hunt, Ian, Lam, Joseph S, Dean, Charles R

“…Gram-negative outer membrane (OM) integrity is maintained in part by Mg(2+) cross-links between phosphates on lipid A and on core sugars of adjacent…”
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Determinants of Antibacterial Spectrum and Resistance Potential of the Elongation Factor G Inhibitor Argyrin B in Key Gram-Negative Pathogens by Jones, Adriana K, Woods, Angela L, Takeoka, Kenneth T, Shen, Xiaoyu, Wei, Jun-Rong, Caughlan, Ruth E, Dean, Charles R

“…Argyrins are natural products with antibacterial activity against Gram-negative pathogens, such as , , and We previously showed that argyrin B targets…”
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Mutations Reducing In Vitro Susceptibility to Novel LpxC Inhibitors in Pseudomonas aeruginosa and Interplay of Efflux and Nonefflux Mechanisms by Jones, Adriana K, Caughlan, Ruth E, Woods, Angela L, Uehara, Kyoko, Xie, Lili, Barnes, S Whitney, Walker, John R, Thompson, Katherine V, Ranjitkar, Srijan, Lee, Patrick S, Dean, Charles R

“…Upregulated expression of efflux pumps, target mutations, LpxC protein overexpression, and mutations in were previously shown to mediate single-step resistance…”
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Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase by Kreamer, Naomi N. K., Chopra, Rajiv, Caughlan, Ruth E., Fabbro, Doriano, Fang, Eric, Gee, Patricia, Hunt, Ian, Li, Min, Leon, Barbara C., Muller, Lionel, Vash, Brian, Woods, Angela L., Stams, Travis, Dean, Charles R., Uehara, Tsuyoshi

“…Phosphorylation of Pseudomonas aeruginosa lipopolysaccharide (LPS) is important for maintaining outer membrane integrity and intrinsic antibiotic resistance…”
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Identification of elongation factor G as the conserved cellular target of argyrin B by Nyfeler, Beat, Hoepfner, Dominic, Palestrant, Deborah, Kirby, Christina A, Whitehead, Lewis, Yu, Robert, Deng, Gejing, Caughlan, Ruth E, Woods, Angela L, Jones, Adriana K, Barnes, S Whitney, Walker, John R, Gaulis, Swann, Hauy, Ervan, Brachmann, Saskia M, Krastel, Philipp, Studer, Christian, Riedl, Ralph, Estoppey, David, Aust, Thomas, Movva, N Rao, Wang, Zuncai, Salcius, Michael, Michaud, Gregory A, McAllister, Gregory, Murphy, Leon O, Tallarico, John A, Wilson, Christopher J, Dean, Charles R

“…Argyrins, produced by myxobacteria and actinomycetes, are cyclic octapeptides with antibacterial and antitumor activity. Here, we identify elongation factor G…”
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