Search Results - "CASTELIJNS, Bas"

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  1. 1

    Hominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patients by Castelijns, Bas, Baak, Mirna L., Timpanaro, Ilia S., Wiggers, Caroline R. M., Vermunt, Marit W., Shang, Peng, Kondova, Ivanela, Geeven, Geert, Bianchi, Valerio, de Laat, Wouter, Geijsen, Niels, Creyghton, Menno P.

    Published in Nature communications (16-01-2020)
    “…Speciation is associated with substantial rewiring of the regulatory circuitry underlying the expression of genes. Determining which changes are relevant and…”
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    Epigenomic annotation of gene regulatory alterations during evolution of the primate brain by Vermunt, Marit W, Tan, Sander C, Castelijns, Bas, Geeven, Geert, Reinink, Peter, de Bruijn, Ewart, Kondova, Ivanela, Persengiev, Stephan, Bontrop, Ronald, Cuppen, Edwin, de Laat, Wouter, Creyghton, Menno P

    Published in Nature neuroscience (01-03-2016)
    “…Gene-regulatory elements are drivers of evolutionary divergence, yet where these are located and which are evolutionarily relevant is unclear. In this work,…”
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  4. 4

    Conventional dendritic cells type 1 are strongly enriched, quiescent and relatively tolerogenic in local inflammatory arthritis by Boltjes, Arjan, Samat, Anoushka Ashok Kumar, Plantinga, Maud, Mokry, Michal, Castelijns, Bas, Swart, Joost F, Vastert, Sebastiaan J, Creyghton, Menno, Nierkens, Stefan, van Loosdregt, Jorg, van Wijk, Femke

    Published in Frontiers in immunology (04-01-2023)
    “…Dendritic cells (DC) are crucial for initiating and shaping immune responses. So far, little is known about the functional specialization of human DC subsets…”
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  5. 5

    GoldenBraid 2.0: A Comprehensive DNA Assembly Framework for Plant Synthetic Biology by Sarrion-Perdigones, Alejandro, Vazquez-Vilar, Marta, Palací, Jorge, Castelijns, Bas, Forment, Javier, Ziarsolo, Peio, Blanca, José, Granell, Antonio, Orzaez, Diego

    Published in Plant physiology (Bethesda) (01-07-2013)
    “…Plant synthetic biology aims to apply engineering principles to plant genetic design. One strategic requirement of plant synthetic biology is the adoption of…”
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  6. 6

    Recently Evolved Enhancers Emerge with High Interindividual Variability and Less Frequently Associate with Disease by Castelijns, Bas, Baak, Mirna L., Geeven, Geert, Vermunt, Marit W., Wiggers, Caroline R.M., Timpanaro, Ilia S., Kondova, Ivanela, de Laat, Wouter, Creyghton, Menno P.

    Published in Cell reports (Cambridge) (23-06-2020)
    “…Mutations in non-coding regulatory DNA such as enhancers underlie a wide variety of diseases including developmental disorders and cancer. As enhancers rapidly…”
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    A coat-independent superinfection exclusion rapidly imposed in Nicotiana benthamiana cells by tobacco mosaic virus is not prevented by depletion of the movement protein by Julve, José Manuel, Gandía, Antoni, Fernández-del-Carmen, Asun, Sarrion-Perdigones, Alejandro, Castelijns, Bas, Granell, Antonio, Orzaez, Diego

    Published in Plant molecular biology (01-04-2013)
    “…New evidence is emerging which indicates that population variants in plant virus infections are not uniformly distributed along the plant, but structured in a…”
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  9. 9

    GoldenBraid 2.0: A Comprehensive DNA Assembly Framework for Plant Synthetic Biology1[C][W][OA] by Sarrion-Perdigones, Alejandro, Vazquez-Vilar, Marta, Palací, Jorge, Castelijns, Bas, Forment, Javier, Ziarsolo, Peio, Blanca, José, Granell, Antonio, Orzaez, Diego

    Published in Plant physiology (Bethesda) (13-05-2013)
    “…GoldenBraid 2.0 is a comprehensive technological framework that facilitates the construction of increasingly complex multigene structures and exchange of…”
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    A novel microscopy-based high-throughput screening method to identify proteins that regulate global histone modification levels by Baas, Roy, Lelieveld, Daphne, van Teeffelen, Hetty, Lijnzaad, Philip, Castelijns, Bas, van Schaik, F M, Vermeulen, Michiel, Egan, David A, Timmers, H Th Marc, de Graaf, Petra

    Published in Journal of biomolecular screening (01-02-2014)
    “…Posttranslational modifications of histones play an important role in the regulation of gene expression and chromatin structure in eukaryotes. The balance…”
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