Search Results - "CASTAÑEDA, JAVIER"
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Real-World Performance of the MiniMed™ 780G System: First Report of Outcomes from 4120 Users
Published in Diabetes technology & therapeutics (01-02-2022)“…The MiniMed™ 780G system includes an advanced hybrid closed loop (AHCL) algorithm that provides both automated basal and correction bolus insulin delivery. The…”
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Time in Tight Glucose Range in Type 1 Diabetes: Predictive Factors and Achievable Targets in Real-World Users of the MiniMed 780G System
Published in Diabetes care (01-05-2024)“…We studied time in tight range (TITR) (70-140 mg/dL) in real-world users of the MiniMed 780G system (MM780G). CareLink Personal data were extracted (August…”
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Comparison of MiniMed 780G system performance in users aged younger and older than 15 years: Evidence from 12 870 real‐world users
Published in Diabetes, obesity & metabolism (01-07-2022)“…Aim To investigate real‐world glycaemic outcomes and goals achieved by users of the MiniMed 780G advanced hybrid closed loop (AHCL) system aged younger and…”
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The significance of coefficient of variation as a measure of hypoglycaemia risk and glycaemic control in real world users of the automated insulin delivery MiniMed 780G system
Published in Diabetes, obesity & metabolism (01-09-2023)“…Aim Use of the MiniMed 780G system (MM780G) can result in a reduction in mean and standard deviation (SD) of sensor glucose (SG) values. We assessed the…”
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Predictors of time in target glucose range in real‐world users of the MiniMed 780G system
Published in Diabetes, obesity & metabolism (01-11-2022)“…Aim Automated insulin delivery systems have improved glycaemic control in people with type 1 diabetes mellitus. The analysis investigated predictors of…”
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Celebrating the Data from 100,000 Real-World Users of the MiniMed™ 780G System in Europe, Middle East, and Africa Collected Over 3 Years: From Data to Clinical Evidence
Published in Diabetes technology & therapeutics (01-03-2024)“…The present report celebrates the benchmarking of 100,000 MiniMed™ 780G system users in Europe, Middle East, and Africa (EMEA) and summarizes the major…”
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Real‐world performance of the MiniMed 780G advanced hybrid closed loop system in Latin America: Substantial improvement in glycaemic control with each technology iteration of the MiniMed automated insulin delivery system
Published in Diabetes, obesity & metabolism (01-06-2023)“…Aim We studied real‐world performance of MiniMed (MM) 780G system users from Argentina, Brazil, Colombia and Chile (geographical analysis), and the effect of…”
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Antifungal Synergy: Mechanistic Insights into the R-1-R Peptide and Bidens pilosa Extract as Potent Therapeutics against Candida spp. through Proteomics
Published in International journal of molecular sciences (16-08-2024)“…Previous reports have demonstrated that the peptide derived from LfcinB, R-1-R, exhibits anti- activity, which is enhanced when combined with an extract from…”
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Future of Time-in-Range Goals in the Era of Advanced Hybrid Closed-Loop Automated Insulin Delivery Systems
Published in Diabetes technology & therapeutics (01-03-2024)“…The concept of maintaining blood glucose levels within the 70-180 mg/dL range, known as time-in-range, has raised questions regarding its representation of…”
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Antibacterial Activity of Synthetic Peptides Derived from Lactoferricin against Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212
Published in BioMed research international (01-01-2015)“…Peptides derived from human and bovine lactoferricin were designed, synthesized, purified, and characterized using RP-HPLC and MALDI-TOF-MS. Specific changes…”
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Generating real‐world evidence on diabetes technology using the CareLink Personal data management system
Published in Diabetes, obesity & metabolism (01-11-2024)“…Aim To establish trust in real‐world evidence (RWE) derived from CareLink Personal (CP), Medtronic's data management system for MiniMed system users, we show…”
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Twelve-Month Real-World Use of an Advanced Hybrid Closed-Loop System Versus Previous Therapy in a Dutch Center For Specialized Type 1 Diabetes Care
Published in Journal of diabetes science and technology (28-10-2024)“…Complexity of glucose regulation in persons with type 1 diabetes (PWDs) necessitates increased automation of insulin delivery (AID). This study aimed to…”
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The MiniMed 780G automated insulin delivery system adapts to substantial changes in daily routine: Lessons from real world users during Ramadan
Published in Diabetes, obesity & metabolism (01-03-2024)“…Aim To report on the effectiveness and safety of the MiniMed 780G automated insulin delivery system in real‐world users during the month of Ramadan. Materials…”
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When Intensive Insulin Therapy (MDI) Fails in Patients With Type 2 Diabetes: Switching to GLP-1 Receptor Agonist Versus Insulin Pump
Published in Diabetes care (01-08-2016)“…Treatment with insulin, alone or with oral or injectable hypoglycemic agents, is becoming increasingly common in patients with type 2 diabetes. However,…”
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Advanced Hybrid Closed Loop in Adult Population With Type 1 Diabetes: A Substudy From the ADAPT Randomized Controlled Trial in Users of Real-Time Continuous Glucose Monitoring
Published in Journal of diabetes science and technology (01-09-2024)“…Background: This analysis reports the findings from a predefined exploratory cohort (cohort B) from the ADAPT (ADvanced Hybrid Closed Loop Study in Adult…”
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The interdependence of targets for continuous glucose monitoring outcomes in type 1 diabetes with automated insulin delivery
Published in Diabetes, obesity & metabolism (01-12-2024)“…Aim The aim was to determine the interdependence of targets for glucose management indicator (GMI), time within the ranges of 70–180 mg/dL (TIR) and 70–140…”
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Efficacy and safety of suspend-before-low insulin pump technology in hypoglycaemia-prone adults with type 1 diabetes (SMILE): an open-label randomised controlled trial
Published in The lancet. Diabetes & endocrinology (01-06-2019)“…Hypoglycaemia unawareness and severe hypoglycaemia can increase fear of hypoglycaemia and the risk of subsequent hypoglycaemic events. We aimed to assess the…”
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In‐house standards derived from doping peptides: Enzymatic and serum stability and degradation profile of GHRP and GHRH‐related peptides
Published in Biomedical chromatography (01-12-2023)“…Abstract Matrix effect and sample pretreatment significantly affect the percentage recovery of peptides in biological matrices, affecting the method robustness…”
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Obtaining an immunoaffinity monolithic material: poly(GMA--EDMA) functionalized with an HPV-derived peptide using a thiol-maleimide reaction
Published in RSC advances (21-01-2021)“…Metabolites have great potential for the design of biomarkers, since their presence or absence provides valuable information about a biological system. In this…”
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Evaluating the In Vitro Activity and Safety of Modified LfcinB Peptides as Potential Colon Anticancer Agents: Cell Line Studies and Insect-Based Toxicity Assessments
Published in ACS omega (17-10-2023)“…Anticancer peptides are increasingly being considered as alternative treatments for cancer due to their potency, selectivity, and low toxicity. Previously, the…”
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