Search Results - "CASPER, L"
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1
Directing the Activation of Donor–Acceptor Cyclopropanes Towards Stereoselective 1,3‐Dipolar Cycloaddition Reactions by Brønsted Base Catalysis
Published in Angewandte Chemie International Edition (18-09-2017)“…The first stereoselective organocatalyzed [3+2] cycloaddition reaction of donor‐acceptor cyclopropanes is presented. It is demonstrated that by applying an…”
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2
Printed artificial cilia from liquid-crystal network actuators modularly driven by light
Published in Nature materials (01-08-2009)“…Polymeric microactuators are potentially useful in micromechanical systems and lab-on-a-chip systems. However, manufacturing of miniature polymeric actuators…”
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3
Construction of C‐N Atropisomers by Aminocatalytic Enantioselective Addition of Indole‐2‐carboxaldehydes to o‐Quinone Derivatives
Published in Chemistry : a European journal (26-10-2022)“…The first atroposelective aminocatalytic methodology for the construction of C−N atropisomers is presented. The synthesis of this class of axially chiral…”
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4
Enantioselective Synthesis of Tropane Scaffolds by an Organocatalyzed 1,3‐Dipolar Cycloaddition of 3‐Oxidopyridinium Betaines and Dienamines
Published in Chemistry : a European journal (01-09-2023)“…Tropane alkaloids constitute a compound‐class which is structurally defined by a central 8‐azabicyclo[3.2.1]octane core. A diverse bioactivity profile combined…”
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5
Umpolung Strategy for α‐Functionalization of Aldehydes for the Addition of Thiols and other Nucleophiles
Published in Angewandte Chemie International Edition (02-12-2019)“…Nucleophile–nucleophile coupling is a challenging transformation in organic chemistry. Herein we present a novel umpolung strategy for α‐functionalization of…”
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6
A Direct Organocatalytic Enantioselective Route to Functionalized trans‐Diels–Alder Products Having the Norcarane Scaffold
Published in Angewandte Chemie International Edition (09-08-2021)“…An enantioselective methodology to construct trans‐Diels–Alder scaffolds by organocatalysis with excellent selectivity, high yield and up to five contiguous…”
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7
Multiple sclerosis risk variants influence the peripheral B‐cell compartment early in life in the general population
Published in European journal of neurology (01-02-2023)“…Background and purpose Multiple sclerosis (MS) is associated with abnormal B‐cell function, and MS genetic risk alleles affect multiple genes that are…”
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8
An Experience-Based Direct Generation Approach to Automatic Image Cropping
Published in IEEE access (2021)“…Automatic Image Cropping is a challenging task with many practical downstream applications. The task is often divided into sub-problems - generating cropping…”
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9
Bending Dynamics and Directionality Reversal in Liquid Crystal Network Photoactuators
Published in Macromolecules (25-11-2008)“…Liquid crystalline photoactuators typically bend toward the light source, driven by the isomerization of azobenzene. In samples with a relatively large…”
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10
Controlling Surface Morphology of Electrospun Polystyrene Fibers: Effect of Humidity and Molecular Weight in the Electrospinning Process
Published in Macromolecules (27-01-2004)“…Electrospinning is a technique used to produce micron to submicron diameter polymeric fibers. The surface of electrospun fibers is important when considering…”
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11
Catalytic Enantioselective Synthesis of Tetrahydocarbazoles and Exocyclic Pictet–Spengler-Type Reactions
Published in Organic letters (02-12-2016)“…A synthetic strategy for the synthesis of chiral tetrahydrocarbazoles (THCAs) has been developed. The strategy relies on two types of 6-exo-trig cyclization of…”
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12
T cell composition and polygenic multiple sclerosis risk: A population‐based study in children
Published in European journal of neurology (01-11-2021)“…Background and purpose Patients with multiple sclerosis (MS) have altered T cell function and composition. Common genetic risk variants for MS affect proteins…”
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13
Pasiflora proteins are novel core components of the septate junction
Published in Development (Cambridge) (01-09-2015)“…Epithelial sheets play essential roles as selective barriers insulating the body from the environment and establishing distinct chemical compartments within…”
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14
Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulators
Published in Organic & biomolecular chemistry (14-02-2013)“…Many bacterial species are capable of assessing their local population densities through a cell-cell signaling mechanism termed quorum sensing (QS). This…”
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15
Ruthenium Hydride/Brønsted Acid-Catalyzed Tandem Isomerization/N‑Acyliminium Cyclization Sequence for the Synthesis of Tetrahydro-β-carbolines
Published in Journal of organic chemistry (20-12-2013)“…This paper describes an efficient tandem sequence for the synthesis of 1,2,3,4-tetrahydro-β-carbolines (THBCs) relying on a ruthenium hydride/Brønsted…”
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16
Synthesis of Oxacyclic Scaffolds via Dual Ruthenium Hydride/Brønsted Acid-Catalyzed Isomerization/Cyclization of Allylic Ethers
Published in Chemistry : a European journal (17-03-2014)“…A ruthenium hydride/Brønsted acid‐catalyzed tandem sequence is reported for the synthesis of 1,3,4,9‐tetrahydropyrano[3,4‐b]indoles (THPIs) and related…”
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17
Screening of Oropharynx and Anorectum Increases Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae Infection in Female STD Clinic Visitors
Published in Sexually transmitted diseases (01-09-2011)“…Background: The relevance of screening of oropharynx and anorectum in addition to endocervical tests for detection of Chlamydia trachomatis and Neisseria…”
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18
The establishment of sexual identity in the Drosophila germline
Published in Development (Cambridge) (15-11-2009)“…The establishment of sexual identity is a crucial step of germ cell development in sexually reproducing organisms. Sex determination in the germline is…”
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Impact of a Palliative Care Consultation Team on Cancer-Related Symptoms in Advanced Cancer Patients Referred to an Outpatient Supportive Care Clinic
Published in Journal of pain and symptom management (2011)“…Abstract Context Patients with advanced cancer may develop severe physical and psychosocial symptoms. There are limited data on the impact of an outpatient…”
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20
Synthesis of tetrahydro-β-carbolines via isomerization of N-allyltryptamines: a metal-catalyzed variation on the Pictet-Spengler theme
Published in Chemical communications (Cambridge, England) (04-04-2012)“…An efficient and broadly applicable alternative to the classical Pictet-Spengler synthesis of tetrahydro-β-carbolines is presented. The method relies on…”
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