Search Results - "CASOLI, Claudio"
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Highlights on distinctive structural and functional properties of HTLV Tax proteins
Published in Frontiers in microbiology (09-09-2013)“…Human T cell leukemia viruses (HTLVs) are complex human retroviruses of the Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and…”
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Antibody complementarity-determining regions (CDRs) can display differential antimicrobial, antiviral and antitumor activities
Published in PloS one (11-06-2008)“…Complementarity-determining regions (CDRs) are immunoglobulin (Ig) hypervariable domains that determine specific antibody (Ab) binding. We have shown that…”
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Temporal regulation of HTLV-2 expression in infected cell lines and patients: evidence for distinct expression kinetics with nuclear accumulation of APH-2 mRNA
Published in Retrovirology (13-09-2012)“…Human T-cell leukemia virus types 1 and 2 (HTLV-1 and HTLV-2) are delta retroviruses with similar genetic organization. Although both viruses immortalize…”
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Postgenomic up-regulation of CCL3L1 expression in HTLV-2–infected persons curtails HIV-1 replication
Published in Blood (01-03-2007)“…Leukocytes of persons coinfected with HTLV-2 and HIV-1 secrete chemokines that prevent CCR5-dependent (R5) HIV-1 infection of CD4+ T cells and macrophages,…”
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Inhibition of Human T Cell Leukemia Virus Type 2 Replication by the Suppressive Action of Class II Transactivator and Nuclear Factor Y
Published in Proceedings of the National Academy of Sciences - PNAS (22-08-2006)“…The master regulator of MHC-II gene transcription, class II transactivator (CIITA), acts as a potent inhibitor of human T cell leukemia virus type 2 (HTLV-2)…”
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Vaccination of lactating dairy cows for the prevention of aflatoxin B1 carry over in milk
Published in PloS one (2011)“…The potential of anaflatoxin B(1) (AnAFB(1)) conjugated to keyhole limpet hemocyanin (KLH) as a vaccine (AnAFB(1)-KLH) in controlling the carry over of the…”
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Analysis of temporal expression of HTLV-2 reveals similarities and functional differences from HTLV-1
Published in Retrovirology (06-06-2011)Get full text
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Kinetics of human-T cell leukemia virus type 2 (HTLV-2) mRNA expression in PBMCs isolated from infected subjects
Published in Retrovirology (24-09-2009)Get full text
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A dual defensive role of CIITA against retroviral infections
Published in Retrovirology (21-12-2006)Get full text
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Molecular and phylogenetic analysis of HIV-1 variants circulating in Italy
Published in Infectious agents and cancer (10-10-2008)“…The continuous identification of HIV-1 non-B subtypes and recombinant forms in Italy indicates the need of constant molecular epidemiology survey of genetic…”
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Anti-CD4-gp120 complex antibodies in long-term non-progressors HIV-1 positive patients: a role in slowing disease progression?
Published in Retrovirology (21-12-2006)Get full text
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Antiretroviral Activity of Thiosemicarbazone Metal Complexes
Published in Journal of medicinal chemistry (23-12-2010)“…Thiosemicarbazones display a wide antimicrobial activity by targeting bacteria, fungi, and viruses. Here, we report our studies on the antiviral activity of…”
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7he MHC Class II Transactivator (CIITA): A Physiologic Inhibitor of HTLV-2 Retroviral Infection
Published in Retrovirology (08-12-2005)Get full text
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Stable changes in CD4+ T lymphocyte miRNA expression after exposure to HIV-1
Published in Blood (28-06-2012)“…MicroRNAs (miRNAs) inhibit HIV-1 expression by either modulating host innate immunity or by directly interfering with viral mRNAs. We evaluated the expression…”
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Identification of TRIM22 single nucleotide polymorphisms associated with loss of inhibition of HIV-1 transcription and advanced HIV-1 disease
Published in AIDS (London) (24-09-2013)“…OBJECTIVE(S):Tripartite motif-containing 22 (TRIM22) is an interferon-induced protein that inhibits HIV-1 transcription and replication in vitro. Two single…”
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The degree of HIV-1 amino acid variability is strictly related to different disease progression rates
Published in Virus genes (01-08-2018)“…The aim of this study is to evaluate the amino acid variability of HIV-1 Gp41, C2–V3, and Nef in a group of patients characterized by different disease…”
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A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents
Published in Scientific reports (11-10-2016)“…A phosphorylated peptide, named K40H, derived from the constant region of IgMs was detected in human serum by liquid chromatography coupled to high-resolution…”
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Copper(II) and Cobalt(III) Pyridoxal Thiosemicarbazone Complexes with Nitroprusside as Counterion: Syntheses, Electronic Properties, and Antileukemic Activity
Published in Journal of medicinal chemistry (10-03-2005)“…In this paper the syntheses of new pyridoxal thiosemicarbazone copper(II) and cobalt(III) complexes with nitroprusside as a counterion and tests on the…”
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HTLV-1/-2 and HIV-1 co-infections: retroviral interference on host immune status
Published in Frontiers in microbiology (23-12-2013)“…The human retroviruses HIV-1 and HTLV-1/HTLV-2 share similar routes of transmission but cause significantly different diseases. In this review we have outlined…”
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