Search Results - "CASHIN, C H"

Biologic properties of romazarit (Ro 31-3948), a potential disease-modifying antirheumatic drug by Bloxham, D P, Bradshaw, D, Cashin, C H, Dodge, B B, Lewis, E J, Westmacott, D, Self, C R

“…The biologic effects of a new potential disease-modifying antirheumatic drug, romazarit (Ro 31-3948,…”
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Angiogenesis and chronic inflammation. Meeting of the British Inflammation Research Association (BIRAs) 5th June, 1990. Roche Products, Welwyn Garden City by Cashin, C H, Dodge, B, Harper, G P

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The effect of retinoids on the skin reaction and swelling seen 7 days after adjuvant injection in the rat paw by Cashin, C H, Lewis, E J

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The Chemistry and Pharmacology of a Series of Cycloalkanespiro-5'-hydantoins by Oldfield, W, Cashin, C. H

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Automated quantification of rat plasma acute phase reactants in experimental inflammation by Lewis, E J, Bishop, J, Cashin, C H

“…Methods are described for the quantification of certain acute phase reactants (albumin, iron, fibrinogen, seromucoid, haptoglobin, and ceruloplasmin) in small…”
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The induction of an erosive arthropathy in the guinea pig with copper II bisglycinate and its treatment with antirheumatic drugs by Cashin, C H

“…Single intra-articular injections of copper II bisglycinate [Cu(II)gly] (30-300 micrograms) into guinea-pig knee joints induce progressive joint degradation…”
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Pharmacological and biochemical activities of tenoxicam (Ro 12-0068), a new non-steroidal anti-inflammatory drug by Bradshaw, D, Cashin, C H, Kennedy, A J, Roberts, N A

“…Tenoxicam, a new non-steroidal anti-inflammatory drug has been compared with piroxicam and indomethacin in a range of pharmacological and biochemical…”
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An apparatus for testing anticonvulsant drugs by electroshock seizures in mice by CASHIN, C H, JACKSON, H

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Prostaglandin E2 and collagenase release by cultured talus from type II collagen arthritis rats by Westmacott, D, Hawkes, J E, Wadsworth, J, Cashin, C H, Cline, A, Bradshaw, D, Bloxham, D P

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Substituted Anilinopyridine Carboxylic Acids with Antiinflammatory Activity by Evans, D., Hallwood, K. S., Cashin, C. H., Jackson, H.

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An assessment of the delayed hypersensitivity reaction to methylated bovine serum albumin in the mouse and its use in the evaluation of drug effects on cell mediated immune reactions by Cashin, C H, Gill, J, Jones, S A, Kennedy, A J

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The assay of anti‐pyretic drugs in mice, using intracerebral injection of pyretogenins by CASHIN, C. H., HEADING, CHRISTINE E.

“…1 A simple, cheap, and reliable method is described for the screening of new compounds for anti‐pyretic activity. It involves the intracerebral injection of a…”
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Evaluation of hypervitaminosis A in the rat by measurement of tibial bone breaking strain by Cashin, C H, Lewis, E J

“…Using etretinate as a model compound, the bone changes characteristic of hypervitaminosis A were evaluated in the rat in terms of tibial bone-breaking strain…”
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Effect of sympathomimetic drugs in eliciting hypertensive responses to reserpine in the rat, after pretreatment with monoamineoxidase inhibitors by CASHIN, C. H.

“…Summary 1 The effects of some rapidly metabolized sympathomimetic amines, such as β‐phenylethylamine and p‐tyramine, in eliciting hypertensive responses to…”
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An investigation of the effect of anti-inflammatory and anti-rheumatoid drugs in cell-mediated immune arthritis in guinea-pigs by microfocal radiography by Cashin, C H, Doherty, N S, Jeffries, B L, Buckland-Wright, J C

“…Guinea-pigs were sensitized by intra-articular injection of M. tuberculosis (2.0 mg) into one knee joint and arthritis induced in the opposite knee 21 days…”
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Romazarit. A potential disease-modifying antirheumatic drug by Self, Christopher R, Barber, William E, Machin, Peter J, Osbond, John M, Smithen, Carey E, Tong, Brian P, Wickens, James C, Bloxham, David P, Bradshaw, David

“…The synthesis of a series of substituted heterocyclic alkoxypropionic acids is described. They were evaluated for antiinflammatory effects in two animal models…”
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The use of intracerebral pyretogenins in testing for antipyretic activity in conscious mice by Cashin, C H, Heading, C E

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The development of screening tests for D-penicillamine-like antirheumatic activity based on in vivo interactions with copper by Cashin, C H, Lewis, E J, Burden, T

“…Injections of labile copper complexes such as copper II bisglycinate [Cu(II)gly] induce marked inflammatory responses in rats in contrast to stable copper…”
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An injection block for small animals by Brocklehurst, W E, Cashin, C H

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Relation between plasma concentration and therapeutic efficacy of a new anti-inflammatory compound, benoxaprofen (LRCL 3794) in rats with adjuvant-induced arthritis by Chatfield, D H, Cashin, C H, Kitchen, E A, Green, J N

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