Search Results - "CASAGRANDE, Francesca"

α-Synuclein is a Novel Microtubule Dynamase by Cartelli, Daniele, Aliverti, Alessandro, Barbiroli, Alberto, Santambrogio, Carlo, Ragg, Enzio M., Casagrande, Francesca V.M., Cantele, Francesca, Beltramone, Silvia, Marangon, Jacopo, De Gregorio, Carmelita, Pandini, Vittorio, Emanuele, Marco, Chieregatti, Evelina, Pieraccini, Stefano, Holmqvist, Staffan, Bubacco, Luigi, Roybon, Laurent, Pezzoli, Gianni, Grandori, Rita, Arnal, Isabelle, Cappelletti, Graziella

“…α-Synuclein is a presynaptic protein associated to Parkinson’s disease, which is unstructured when free in the cytoplasm and adopts α helical conformation when…”
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The imbalance between dynamic and stable microtubules underlies neurodegeneration induced by 2,5-hexanedione by Casagrande, Francesca V.M., Amadeo, Alida, Cartelli, Daniele, Calogero, Alessandra M., Modena, Debora, Costa, Ilaria, Cantele, Francesca, Onelli, Elisabetta, Moscatelli, Alessandra, Ascagni, Miriam, Pezzoli, Gianni, Cappelletti, Graziella

“…Exposure to environmental toxins, including hydrocarbon solvents, increases the risk of developing Parkinson's disease. An emergent hypothesis considers…”
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Microtubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts by Cartelli, Daniele, Goldwurm, Stefano, Casagrande, Francesca, Pezzoli, Gianni, Cappelletti, Graziella

“…Data from both toxin-based and gene-based models suggest that dysfunction of the microtubule system contributes to the pathogenesis of Parkinson's disease,…”
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Microtubule Alterations Occur Early in Experimental Parkinsonism and The Microtubule Stabilizer Epothilone D Is Neuroprotective by Cartelli, Daniele, Casagrande, Francesca, Busceti, Carla Letizia, Bucci, Domenico, Molinaro, Gemma, Traficante, Anna, Passarella, Daniele, Giavini, Erminio, Pezzoli, Gianni, Battaglia, Giuseppe, Cappelletti, Graziella

“…The role of microtubule (MT) dysfunction in Parkinson's disease is emerging. It is still unknown whether it is a cause or a consequence of neurodegeneration…”
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SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation by Jevtic, Zivojin, Matafora, Vittoria, Casagrande, Francesca, Santoro, Fabio, Minucci, Saverio, Garre', Massimilliano, Rasouli, Milad, Heidenreich, Olaf, Musco, Giovanna, Schwaller, Jürg, Bachi, Angela

“…Acute myeloid leukemia (AML) is characterized by accumulation of aberrantly differentiated hematopoietic myeloid progenitor cells. The karyotyping-silent…”
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SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development by Falbo, Lucia, Raspelli, Erica, Romeo, Francesco, Fiorani, Simona, Pezzimenti, Federica, Casagrande, Francesca, Costa, Ilaria, Parazzoli, Dario, Costanzo, Vincenzo

“…In several metazoans, the number of active replication origins in embryonic nuclei is higher than in somatic ones, ensuring rapid genome duplication during…”
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Unveiling the mechanistic link between extracellular amyloid fibrils, mechano-signaling and YAP activation in cancer by Farris, Francesco, Elhagh, Alice, Vigorito, Ilaria, Alongi, Nicoletta, Pisati, Federica, Giannattasio, Michele, Casagrande, Francesca, Veghini, Lisa, Corbo, Vincenzo, Tripodo, Claudio, Di Napoli, Arianna, Matafora, Vittoria, Bachi, Angela

“…The tumor microenvironment is a complex ecosystem that plays a critical role in cancer progression and treatment response. Recently, extracellular amyloid…”
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Sex-specific extracerebral complications in patients with aneurysmal subarachnoid hemorrhage by Bögli, Stefan Y, Beham, Sabrina, Hirsbrunner, Laura, Nellessen, Friederike, Casagrande, Francesca, Keller, Emanuela, Brandi, Giovanna

“…Extracerebral complications in patients with aneurysmal subarachnoid hemorrhage (aSAH) often occur during their stay at the neurocritical care unit (NCCU)…”
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Sex-related differences in symptom presentation of patients with aneurysmal subarachnoid hemorrhage [version 2; peer review: 2 approved] by Westphal, Laura Philine, Bögli, Stefan Yu, Werner, Jana, Casagrande, Francesca, Keller, Emanuela, Brandi, Giovanna

“…Background: In patients with myocardial infarction, atypical symptoms at onset have been demonstrated in women. We aimed to investigate the presence of…”
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Eradication of chemotherapy‐resistant CD44+ human ovarian cancer stem cells in mice by intraperitoneal administration of clostridium perfringens enterotoxin by Casagrande, Francesca, Cocco, Emiliano, Bellone, Stefania, Richter, Christine E., Bellone, Marta, Todeschini, Paola, Siegel, Eric, Varughese, Joyce, Arin‐Silasi, Dan, Azodi, Masoud, Rutherford, Thomas J., Pecorelli, Sergio, Schwartz, Peter E., Santin, Alessandro D.

“…BACKGROUND: Emerging evidence has suggested that the capability to sustain tumor formation, growth, and chemotherapy resistance in ovarian as well as other…”
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Correction: Microtubule Destabilization Is Shared by Genetic and Idiopathic Parkinson’s Disease Patient Fibroblasts by Cartelli, Daniele, Goldwurm, Stefano, Casagrande, Francesca, Pezzoli, Gianni, Cappelletti, Graziella

“…Dr. Esteves and colleagues used a Parkinson's disease-derived cellular model, as cytoplasmic hybrid (cybrid) cell lines are, in which the mitochondrial DNA…”
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Human Papillomavirus Type 16 (HPV-16) Virus-Like Particle L1-Specific CD8+ Cytotoxic T Lymphocytes (CTLs) Are Equally Effective as E7-Specific CD8+ CTLs in Killing Autologous HPV-16-Positive Tumor Cells in Cervical Cancer Patients: Implications for L1 Dendritic Cell-Based Therapeutic Vaccines by BELLONE, Stefania, EL-SAHWI, Karim, SCHWARTZ, Peter E, RUTHERFORD, Thomas J, PECORELLI, Sergio, SANTIN, Alessandro D, COCCO, Emiliano, CASAGRANDE, Francesca, CARGNELUTTI, Marilisa, PALMIERI, Michela, BIGNOTTI, Eliana, ROMANI, Chiara, SILASI, Dan-Arin, AZODI, Masoud

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer by Cocco, Emiliano, Casagrande, Francesca, Bellone, Stefania, Richter, Christine E, Bellone, Marta, Todeschini, Paola, Holmberg, Jennie C, Fu, Han Hsuan, Montagna, Michele K, Mor, Gil, Schwartz, Peter E, Arin-Silasi, Dan, Azoudi, Masoud, Rutherford, Thomas J, Abu-Khalaf, Maysa, Pecorelli, Sergio, Santin, Alessandro D

“…Development of innovative, effective therapies against recurrent/chemotherapy-resistant ovarian cancer remains a high priority. Using high-throughput…”
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Parkin absence accelerates microtubule aging in dopaminergic neurons by Cartelli, Daniele, Amadeo, Alida, Calogero, Alessandra Maria, Casagrande, Francesca Vittoria Marialuisa, De Gregorio, Carmelita, Gioria, Mariarosa, Kuzumaki, Naoko, Costa, Ilaria, Sassone, Jenny, Ciammola, Andrea, Hattori, Nobutaka, Okano, Hideyuki, Goldwurm, Stefano, Roybon, Laurent, Pezzoli, Gianni, Cappelletti, Graziella

“…Loss-of-function caused by mutations in the parkin gene (PARK2) lead to early-onset familial Parkinson's disease. Recently, mechanistic studies proved the…”
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Overexpression of EpCAM in Uterine Serous Papillary Carcinoma: Implications for EpCAM-Specific Immunotherapy With Human Monoclonal Antibody Adecatumumab (MT201) by El-Sahwi, Karim, Bellone, Stefania, Cocco, Emiliano, Casagrande, Francesca, Bellone, Marta, Abu-Khalaf, Maysa, Buza, Natalia, Tavassoli, Fattaneh A., Hui, Pei, Rüttinger, Dominik, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter E., Rutherford, Thomas J., Pecorelli, Sergio, Santin, Alessandro D.

“…We evaluated the expression of epithelial cell adhesion molecule (EpCAM) and the potential of MT201 (adecatumumab), a human monoclonal antibody against EpCAM,…”
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Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity by Matafora, Vittoria, Farris, Francesco, Restuccia, Umberto, Tamburri, Simone, Martano, Giuseppe, Bernardelli, Clara, Sofia, Andrea, Pisati, Federica, Casagrande, Francesca, Lazzari, Luca, Marsoni, Silvia, Bonoldi, Emanuela, Bachi, Angela

“…Melanoma progression is generally associated with increased transcriptional activity mediated by the Yes‐associated protein (YAP). Mechanical signals from the…”
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Long-term outcome in new onset refractory status epilepticus: a retrospective study by Stretti, Federica, Bögli, Stefan Yu, Casagrande, Francesca, Eisele, Amanda, Galovic, Marian, Keller, Emanuela, Brandi, Giovanna

“…New onset refractory status epilepticus (NORSE) is a neurologic emergency without an immediately identifiable cause. The complicated and long ICU stay of the…”
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A Highly Luminescent Tetrahydrocurcumin Ir III Complex with Remarkable Photoactivated Anticancer Activity by Colombo, Alessia, Fontani, Mattia, Dragonetti, Claudia, Roberto, Dominique, Williams, J A Gareth, Scotto di Perrotolo, Rossella, Casagrande, Francesca, Barozzi, Sara, Polo, Simona

“…Curcumin has chemopreventative properties against a variety of tumours, but has poor bioavailability. Here, two new bis-cyclometallated iridium(III) complexes…”
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Linking microtubules to Parkinson's disease: the case of parkin by Cappelletti, Graziella, Casagrande, Francesca, Calogero, Alessandra, De Gregorio, Carmelita, Pezzoli, Gianni, Cartelli, Daniele

“…Microtubules (MTs) are dynamic polymers consisting of α/β tubulin dimers and playing a plethora of roles in eukaryotic cells. Looking at neurons, they are key…”
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Sex-related differences in symptom presentation of patients with aneurysmal subarachnoid hemorrhage [version 1; peer review: 1 approved with reservations] by Westphal, Laura Philine, Bögli, Stefan Yu, Werner, Jana, Casagrande, Francesca, Keller, Emanuela, Brandi, Giovanna

“…Background: In patients with myocardial infarction, atypical symptoms at onset have been demonstrated in women. We aimed to investigate the presence of…”
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