Search Results - "CARVALHO, D"
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An Assessment of NASA’s GMAO MERRA-2 Reanalysis Surface Winds
Published in Journal of climate (01-12-2019)“…The quality of MERRA-2 surface wind fields was assessed by comparing them with 10 years of measurements from a wide range of surface wind observing platforms…”
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Author Correction: High-resolution surface temperature changes for Portugal under CMIP6 future climate scenarios
Published in Scientific reports (08-10-2024)Get full text
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High-resolution surface temperature changes for Portugal under CMIP6 future climate scenarios
Published in Scientific reports (26-07-2024)“…Future changes in the mean, maximum and minimum temperature in continental Portugal were investigated using high-resolution future climate projections based on…”
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Epigenetic therapy in immune-oncology
Published in Nature reviews. Cancer (01-03-2019)“…DNA methylation inhibitors have become the mainstay for treatment of certain haematological malignancies. In addition to their abilities to reactivate genes,…”
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Europe, China and the United States: Three different approaches to the development of offshore wind energy
Published in Renewable & sustainable energy reviews (01-07-2019)“…In those countries where wind plays a major role in the energy mix (EU, China and USA) actions have been carried out to develop offshore wind energy, albeit to…”
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Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer
Published in Cancer cell (13-10-2014)“…DNA methylation in promoters is well known to silence genes and is the presumed therapeutic target of methylation inhibitors. Gene body methylation is…”
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TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
Published in Nature communications (08-11-2018)“…The extracellular matrix (ECM) is a key determinant of cancer progression and prognosis. Here we report findings from one of the largest pan-cancer analyses of…”
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Coronavirus Disease 2019 and Parkinsonism: A Non‐post‐encephalitic Case
Published in Movement disorders (01-10-2020)Get full text
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Future surface temperatures over Europe according to CMIP6 climate projections: an analysis with original and bias-corrected data
Published in Climatic change (01-07-2021)“…Future changes in the mean, maximum, and minimum surface temperature over Europe are investigated according to CMIP6 future climate projections. All the…”
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DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
Published in Cell (27-08-2015)“…DNA-demethylating agents have shown clinical anti-tumor efficacy via an unknown mechanism of action. Using a combination of experimental and bioinformatics…”
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Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes
Published in Nature medicine (01-07-2020)“…Definitive diagnosis of intracranial tumors relies on tissue specimens obtained by invasive surgery. Noninvasive diagnostic approaches provide an opportunity…”
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Potential impacts of climate change on European wind energy resource under the CMIP5 future climate projections
Published in Renewable energy (01-02-2017)“…Climate change impact on future European large-scale wind energy resource under the latest IPCC CMIP5 future climate projections were analysed. After assessing…”
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Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA
Published in Nature protocols (01-10-2019)“…Circulating cell-free DNA (cfDNA) comprises small DNA fragments derived from normal and tumor tissue that are released into the bloodstream. Recently,…”
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How well have CMIP3, CMIP5 and CMIP6 future climate projections portrayed the recently observed warming
Published in Scientific reports (14-07-2022)“…Despite the dire conclusions of the Intergovernmental Panel on Climate Change (IPCC) Assessment Reports in terms of global warming and its impacts on Earth’s…”
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Endogenous Retroelements and the Viral Mimicry Response in Cancer Therapy and Cellular Homeostasis
Published in Cancer discovery (01-11-2021)“…Features of the cancer epigenome distinguish cancers from their respective cell of origin and establish therapeutic vulnerabilities that can be exploited…”
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Horizon fractalization in black strings ungravity
Published in The European physical journal. C, Particles and fields (01-03-2023)“…In this paper, we study the scalar (tensor) and vector unparticle corrections for cosmic and black strings. Initially, we consider a static cosmic string…”
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Sensitivity of the WRF model wind simulation and wind energy production estimates to planetary boundary layer parameterizations for onshore and offshore areas in the Iberian Peninsula
Published in Applied energy (15-12-2014)“…•WRF model near surface wind simulation sensitivity to different PBL and SL parameterizations was assessed.•Simulations were evaluated using onshore and…”
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Aridity and desertification in the Mediterranean under EURO-CORDEX future climate change scenarios
Published in Climatic change (01-10-2022)“…This study investigates future aridity changes in the Mediterranean under the RCP4.5 and RCP8.5 IPCC future climate scenarios, using nine bias-corrected,…”
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Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
Published in Nature (London) (03-12-2020)“…Cancer therapies that target epigenetic repressors can mediate their effects by activating retroelements within the human genome. Retroelement transcripts can…”
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WRF wind simulation and wind energy production estimates forced by different reanalyses: Comparison with observed data for Portugal
Published in Applied energy (15-03-2014)“…•Simulated winds and wind energy estimates forced by different reanalysis were evaluated in Portugal.•ERA-Interim reanalysis is the one that likely provides…”
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