Search Results - "CARVALHO, Carla R. O"

Oxidative stress and inflammatory mediators contribute to endothelial dysfunction in high-fat diet-induced obesity in mice by KOBAYASI, Renata, AKAMINE, Eliana H, DAVEL, Ana P, RODRIGUES, Maria A. M, CARVALHO, Carla R. O, ROSSONI, Luciana V

“…We investigated the effects of high-fat diet-induced obesity on vascular proinflammatory factors and oxidative stress on endothelium-dependent relaxation of…”
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Western Diet-Fed ApoE Knockout Male Mice as an Experimental Model of Non-Alcoholic Steatohepatitis by Camargo, Felipe N., Matos, Sandro L., Araujo, Layanne C. C., Carvalho, Carla R. O., Amaral, Andressa G., Camporez, João Paulo

“…One of the consequences of the Western lifestyle and high-fat diet is non-alcoholic fatty liver disease (NAFLD) and its aggressive form, non-alcoholic…”
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Estradiol Protects Female ApoE KO Mice against Western-Diet-Induced Non-Alcoholic Steatohepatitis by Araujo, Layanne C C, Cruz, Alessandra G, Camargo, Felipe N, Sucupira, Felipe G, Moreira, Gabriela V, Matos, Sandro L, Amaral, Andressa G, Murata, Gilson Masahiro, Carvalho, Carla R O, Camporez, Joao Paulo

“…The prevalence of non-alcoholic fatty liver disease (NAFLD) and its severe form, non-alcoholic steatohepatitis (NASH), is higher in men than in women of…”
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Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance by Camporez, João Paulo G, Jornayvaz, François R, Lee, Hui-Young, Kanda, Shoichi, Guigni, Blas A, Kahn, Mario, Samuel, Varman T, Carvalho, Carla R.O, Petersen, Kitt Falk, Jurczak, Michael J, Shulman, Gerald I

“…Estrogen replacement therapy reduces the incidence of type 2 diabetes in postmenopausal women; however, the mechanism is unknown. Therefore, the aim of this…”
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Obesity induced by high-fat diet promotes insulin resistance in the ovary by Akamine, Eliana H, Marçal, Anderson C, Camporez, João Paulo, Hoshida, Mara S, Caperuto, Luciana C, Bevilacqua, Estela, Carvalho, Carla R O

“…Besides the effects on peripheral energy homeostasis, insulin also has an important role in ovarian function. Obesity has a negative effect on fertility, and…”
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A comprehensive review on phytochemicals for fatty liver: are they potential adjuvants? by do Moinho, Taís Menezes, Matos, Sandro Leão, Carvalho, Carla R. O.

“…Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome and, as such, is associated with obesity. With the…”
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Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLD by Araujo, Layanne C. C., Feitosa, Karla B., Murata, Gilson M., Furigo, Isadora C., Teixeira, Simone A., Lucena, Camila F., Ribeiro, Luciene M., Muscará, Marcelo N., Costa, Soraia K. P., Donato, José, Bordin, Silvana, Curi, Rui, Carvalho, Carla R. O.

“…We investigated the effect of the crude herbal extract from Uncaria tomentosa (UT) on non-alcoholic fatty liver disease (NAFLD) in two models of obesity: high…”
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Reference Gene and Protein Expression Levels in Two Different NAFLD Mouse Models by Araujo, Layanne C. C., Carvalho, Carla Roberta de Oliveira, Bordin, Silvana

“…The expression levels of some reference genes and proteins are used for data normalization and quantification. However, these levels can change in response to…”
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Melatonin improves insulin sensitivity independently of weight loss in old obese rats by Zanuto, Ricardo, Siqueira-Filho, Mário A., Caperuto, Luciana C., Bacurau, Reury F. P., Hirata, Emiko, Peliciari-Garcia, Rodrigo A., do Amaral, Fernanda Gaspar, Marçal, Anderson C., Ribeiro, Luciene M., Camporez, João P. G., Carpinelli, Ângelo Rafael, Bordin, Silvana, Cipolla-Neto, José, Carvalho, Carla R. O.

“…In aged rats, insulin signaling pathway (ISP) is impaired in tissues that play a pivotal role in glucose homeostasis, such as liver, skeletal muscle, and…”
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Distinct regulation of IRS proteins in adipose tissue from obese aged and dexamethasone-treated rats by Caperuto, Luciana C, Anhê, Gabriel F, Amanso, Angélica M, Ribeiro, Luciene M, Medina, Mayrin C, Souza, Lilian C, Carvalho, Olga M F, Bordin, Silvana, Saad, Mário J A, Carvalho, Carla R O

“…In the present study, we investigated the protein levels and phosphorylation status of the insulin receptor and insulin receptor substrates (IRS-1, IRS-2, and…”
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In vivo activation of insulin receptor tyrosine kinase by melatonin in the rat hypothalamus by Anhê, Gabriel F., Caperuto, Luciana C., Pereira‐Da‐Silva, Marcio, Souza, Lilian C., Hirata, A. Emiko, Velloso, Lício A., Cipolla‐Neto, José, Carvalho, Carla R. O.

“…Melatonin is the pineal hormone that acts via a pertussis toxin‐sensitive G‐protein to inhibit adenylate cyclase. However, the intracellular signalling effects…”
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Role of fatty acids in the transition from anaerobic to aerobic metabolism in skeletal muscle during exercise by Hirabara, Sandro M., Silveira, Leonardo R., Abdulkader, Fernando R. M., Alberici, Luciane C., Procopio, Joaquim, Carvalho, Carla R. O., Pithon-Curi, Tania C., Curi, Rui

“…In moderate physical exercise, the transition from predominantly anaerobic towards predominantly aerobic metabolism is a key step to improve performance…”
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Novel Signal Transduction Pathway for Luteinizing Hormone and Its Interaction with Insulin: Activation of Janus Kinase/Signal Transducer and Activator of Transcription and Phosphoinositol 3-Kinase/Akt Pathways by Carvalho, Carla R. O, Carvalheira, José B. C, Lima, Maria H. M, Zimmerman, Suzana F, Caperuto, Luciana C, Amanso, Angélica, Gasparetti, Alessandra L, Meneghetti, Vainer, Zimmerman, Leonardo F, Velloso, Licio A, Saad, Mario J. A

“…The actions of LH are mediated through a single class of cell surface LH/human chorionic gonadotropin receptor, which is a member of the G protein-coupled…”
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Diet-induced obesity impairs AKT signalling in the retina and causes retinal degeneration by Marçal, Anderson C., Leonelli, Mauro, Fiamoncini, Jarlei, Deschamps, Francisco C., Rodrigues, Maria A. M., Curi, Rui, Carpinelli, Angelo R., Britto, Luiz R. G., Carvalho, Carla R. O.

“…Retinopathy, a common complication of diabetes, is characterized by an unbalanced production of nitric oxide (NO), a process regulated by nitric oxide synthase…”
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Insulin temporal sensitivity and its signaling pathway in the rat pineal gland by Peliciari-Garcia, Rodrigo A., Marçal, Anderson C., Silva, Jéssica A., Carmo-Buonfiglio, Daniella, Amaral, Fernanda G., Afeche, Solange Castro, Cipolla-Neto, José, Carvalho, Carla R.O.

“…In our previous work, we reported that the insulin potentiating effect on melatonin synthesis is regulated by a post-transcriptional mechanism. However, the…”
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Metformin acts in the gut and induces gut-liver crosstalk by Tobar, Natália, Rocha, Guilherme Z, Santos, Andrey, Guadagnini, Dioze, Assalin, Heloísa B, Camargo, Juliana A, Gonçalves, Any E S S, Pallis, Flavia R, Oliveira, Alexandre G, Rocco, Silvana A, Neto, Raphael M, de Sousa, Irene Layane, Alborghetti, Marcos R, Sforça, Maurício L, Rodrigues, Patrícia B, Ludwig, Raissa G, Vanzela, Emerielle C, Brunetto, Sergio Q, Boer, Patrícia A, Gontijo, José A R, Geloneze, Bruno, Carvalho, Carla R O, Prada, Patricia O, Folli, Franco, Curi, Rui, Mori, Marcelo A, Vinolo, Marco A R, Ramos, Celso D, Franchini, Kleber G, Tormena, Claudio F, Saad, Mario J A

“…Metformin is the most prescribed drug for DM2, but its site and mechanism of action are still not well established. Here, we investigated the effects of…”
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Kombucha tea improves glucose tolerance and reduces hepatic steatosis in obese mice by Moreira, Gabriela V., Araujo, Layanne C.C., Murata, Gilson M., Matos, Sandro L., Carvalho, Carla R.O.

“…Nonalcoholic fatty liver disease (NAFLD), often associated with obesity, is becoming one of the most common liver diseases worldwide. It is estimated to affect…”
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Up-regulation of the phosphatidylinositol 3-kinase/protein kinase B pathway in the ovary of rats by chronic treatment with hCG and insulin by Lima, Maria H M, Souza, Lílian C, Caperuto, Luciana C, Bevilacqua, Estela, Gasparetti, Alessandra L, Zanuto, Ricardo, Saad, Mario J A, Carvalho, Carla R O

“…Polycystic ovary syndrome (PCOS) manifests as chronic anovulation, ovarian hyperandrogenism, and follicular cysts, which are amplified by insulin as well as…”
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Postpartum glycemic homeostasis in early lactating rats is accompanied by transient and specific increase of soleus insulin response through IRS2/AKT pathway by Anhê, Gabriel F, Hirabara, Sandro M, Turrer, Tatiana C, Caperuto, Luciana C, Anhê, Fernando F, Ribeiro, Luciene M, Marçal, Anderson C, Carvalho, Carla R O, Curi, Rui, Machado, Ubiratan F, Bordin, Silvana

“…It is known that at the moment of delivery immediate lost of conceptus (main site of glucose disposal in late pregnancy) is not able to disturb glucose…”
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Reversal of denervation-induced insulin resistance by SHIP2 protein synthesis blockade by Bertelli, Daniela F, Ueno, Miriam, Amaral, Maria E C, Toyama, Marcos Hikari, Carneiro, Everardo M, Marangoni, Sergio, Carvalho, Carla R O, Saad, Mario J A, Velloso, Licio A, Boschero, A Carlos

“…Short-term muscle denervation is a reproducible model of tissue-specific insulin resistance. To investigate the molecular basis of insulin resistance in…”
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