Search Results - "CARROLL, Andrew J"

Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group by Reshmi, Shalini C., Harvey, Richard C., Roberts, Kathryn G., Stonerock, Eileen, Smith, Amy, Jenkins, Heather, Chen, I-Ming, Valentine, Marc, Liu, Yu, Li, Yongjin, Shao, Ying, Easton, John, Payne-Turner, Debbie, Gu, Zhaohui, Tran, Thai Hoa, Nguyen, Jonathan V., Devidas, Meenakshi, Dai, Yunfeng, Heerema, Nyla A., Carroll, Andrew J., Raetz, Elizabeth A., Borowitz, Michael J., Wood, Brent L., Angiolillo, Anne L., Burke, Michael J., Salzer, Wanda L., Zweidler-McKay, Patrick A., Rabin, Karen R., Carroll, William L., Zhang, Jinghui, Loh, Mignon L., Mullighan, Charles G., Willman, Cheryl L., Gastier-Foster, Julie M., Hunger, Stephen P.

“…Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subtype characterized by genomic alterations that activate cytokine…”
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Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232 by Borowitz, Michael J., Wood, Brent L., Devidas, Meenakshi, Loh, Mignon L., Raetz, Elizabeth A., Salzer, Wanda L., Nachman, James B., Carroll, Andrew J., Heerema, Nyla A., Gastier-Foster, Julie M., Willman, Cheryl L., Dai, Yunfeng, Winick, Naomi J., Hunger, Stephen P., Carroll, William L., Larsen, Eric

“…Minimal residual disease (MRD) is highly prognostic in pediatric B-precursor acute lymphoblastic leukemia (B-ALL). In Children's Oncology Group high-risk B-ALL…”
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Expression and prognostic impact of lncRNAs in acute myeloid leukemia by Garzon, Ramiro, Volinia, Stefano, Papaioannou, Dimitrios, Nicolet, Deedra, Kohlschmidt, Jessica, Yan, Pearlly S, Mrózek, Krzysztof, Bucci, Donna, Carroll, Andrew J, Baer, Maria R, Wetzler, Meir, Carter, Thomas H, Powell, Bayard L, Kolitz, Jonathan E, Moore, Joseph O, Eisfeld, Ann-Kathrin, Blachly, James S, Blum, William, Caligiuri, Michael A, Stone, Richard M, Marcucci, Guido, Croce, Carlo M, Byrd, John C, Bloomfield, Clara D

“…Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides, located within the intergenic stretches or overlapping antisense transcripts of…”
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Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia by MROZEK, Krzysztof, MARCUCCI, Guido, PETTENATI, Mark J, HEEREMA, Nyla A, BLOCK, Annemarie W, PATIL, Shivanand R, BAER, Maria R, KOLITZ, Jonathan E, MOORE, Joseph O, CARROLL, Andrew J, STONE, Richard M, LARSON, Richard A, NICOLET, Deedra, BLOOMFIELD, Clara D, MAHARRY, Kati S, BECKER, Heiko, WHITMAN, Susan P, METZELER, Klaus H, SCHWIND, Sebastian, WU, Yue-Zhong, KOHLSCHMIDT, Jessica

“…To evaluate the prognostic significance of the international European LeukemiaNet (ELN) guidelines for reporting genetic alterations in acute myeloid leukemia…”
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IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study by MARCUCCI, Guido, MAHARRY, Kati, METZELER, Klaus H, POWELL, Bayard L, CARTER, Thomas H, KOLITZ, Jonathan E, WETZLER, Meir, CARROLL, Andrew J, BAER, Maria R, CALIGIURI, Michael A, LARSON, Richard A, BLOOMFIELD, Clara D, WU, Yue-Zhong, RADMACHER, Michael D, MROZEK, Krzysztof, MARGESON, Dean, HOLLAND, Kelsi B, WHITMAN, Susan P, BECKER, Heiko, SCHWIND, Sebastian

“…PURPOSE To analyze the frequency and associations with prognostic markers and outcome of mutations in IDH genes encoding isocitrate dehydrogenases in adult de…”
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FLT3 inhibitor lestaurtinib plus chemotherapy for newly diagnosed KMT2A-rearranged infant acute lymphoblastic leukemia: Children’s Oncology Group trial AALL0631 by Brown, Patrick A., Kairalla, John A., Hilden, Joanne M., Dreyer, ZoAnn E., Carroll, Andrew J., Heerema, Nyla A., Wang, Cindy, Devidas, Meenakshi, Gore, Lia, Salzer, Wanda L., Winick, Naomi J., Carroll, William L., Raetz, Elizabeth A., Borowitz, Michael J., Small, Donald, Loh, Mignon L., Hunger, Stephen P.

“…Infants with KMT2A ‐rearranged acute lymphoblastic leukemia ( KMT2A -r ALL) have a poor prognosis. KMT2A -r ALL overexpresses FLT3, and the FLT3 inhibitor…”
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Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study by Borowitz, Michael J., Devidas, Meenakshi, Hunger, Stephen P., Bowman, W. Paul, Carroll, Andrew J., Carroll, William L., Linda, Stephen, Martin, Paul L., Pullen, D. Jeanette, Viswanatha, David, Willman, Cheryl L., Winick, Naomi, Camitta, Bruce M.

“…Minimal residual disease (MRD) is an important predictor of relapse in acute lymphoblastic leukemia (ALL), but its relationship to other prognostic variables…”
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RUNX1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures by MENDLER, Jason H, MAHARRY, Kati, NICOLET, Deedra, POWELL, Bayard L, CARTER, Thomas H, WETZLER, Meir, MOORE, Joseph O, KOLITZ, Jonathan E, BAER, Maria R, CARROLL, Andrew J, LARSON, Richard A, CALIGIURI, Michael A, RADMACHER, Michael D, MARCUCCI, Guido, BLOOMFIELD, Clara D, MROZEK, Krzysztof, BECKER, Heiko, METZELER, Klaus H, SCHWIND, Sebastian, WHITMAN, Susan P, KHALIFE, Jihane, KOHLSCHMIDT, Jessica

“…To determine the association of RUNX1 mutations with therapeutic outcome in younger and older patients with primary cytogenetically normal acute myeloid…”
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TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study by METZELER, Klaus H, MAHARRY, Kati, WU, Yue-Zhong, BLUM, William, POWELL, Bayard L, CARTER, Thomas H, WETZLER, Meir, MOORE, Joseph O, KOLITZ, Jonathan E, BAER, Maria R, CARROLL, Andrew J, LARSON, Richard A, RADMACHER, Michael D, CALIGIURI, Michael A, MARCUCCI, Guido, BLOOMFIELD, Clara D, MROZEK, Krzysztof, MARGESON, Dean, BECKER, Heiko, CURFMAN, John, HOLLAND, Kelsi B, SCHWIND, Sebastian, WHITMAN, Susan P

“…To determine the frequency of TET2 mutations, their associations with clinical and molecular characteristics and outcome, and the associated gene- and…”
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Age-Related Prognostic Impact of Different Types of DNMT3A Mutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia by MARCUCCI, Guido, METZELER, Klaus H, WU, Yue-Zhong, POWELL, Bayard L, CARTER, Thomas H, KOLITZ, Jonathan E, WETZLER, Meir, CARROLL, Andrew J, BAER, Maria R, MOORE, Joseph O, CALIGIURI, Michael A, LARSON, Richard A, SCHWIND, Sebastian, BLOOMFIELD, Clara D, BECKER, Heiko, MAHARRY, Kati, MROZEK, Krzysztof, RADMACHER, Michael D, KOHLSCHMIDT, Jessica, NICOLET, Deedra, WHITMAN, Susan P

“…To determine the frequency of DNMT3A mutations, their associations with clinical and molecular characteristics and outcome, and the associated gene- and…”
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Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients by MARCUCCI, Guido, MAHARRY, Kati S, SCHWIND, Sebastian, BECKER, Heiko, EISFELD, Ann-Kathrin, CARROLL, Andrew J, POWELL, Bayard L, KOLITZ, Jonathan E, GARZON, Ramiro, CALIGIURI, Michael A, STONE, Richard M, BLOOMFIELD, Clara D, METZELER, Klaus H, VOLINIA, Stefano, WU, Yue-Zhong, MROZEK, Krzysztof, NICOLET, Deedra, KOHLSCHMIDT, Jessica, WHITMAN, Susan P, MENDLER, Jason H

“…To evaluate the impact of miR-155 on the outcome of adults with cytogenetically normal (CN) acute myeloid leukemia (AML) in the context of other clinical and…”
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Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia by Mullighan, Charles G, Collins-Underwood, J Racquel, Phillips, Letha A A, Loudin, Michael G, Liu, Wei, Zhang, Jinghui, Ma, Jing, Coustan-Smith, Elaine, Harvey, Richard C, Willman, Cheryl L, Mikhail, Fady M, Meyer, Julia, Carroll, Andrew J, Williams, Richard T, Cheng, Jinjun, Heerema, Nyla A, Basso, Giuseppe, Pession, Andrea, Pui, Ching-Hon, Raimondi, Susana C, Hunger, Stephen P, Downing, James R, Carroll, William L, Rabin, Karen R

“…Charles Mullighan and colleagues report a recurrent rearrangement of CRLF2 in B-progenitor and Down syndrome-associated acute lymphoblastic leukemia. Their…”
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Epigenetics Meets Genetics in Acute Myeloid Leukemia: Clinical Impact of a Novel Seven-Gene Score by MARCUCCI, Guido, YAN, Pearlly, CURFMAN, John P, WHITMAN, Susan P, EISFELD, Ann-Kathrin, MENDLER, Jason H, SCHWIND, Sebastian, BECKER, Heiko, BÄR, Constance, CARROLL, Andrew J, BAER, Maria R, WETZLER, Meir, MAHARRY, Kati, CARTER, Thomas H, POWELL, Bayard L, KOLITZ, Jonathan E, BYRD, John C, PLASS, Christoph, GARZON, Ramiro, CALIGIURI, Michael A, STONE, Richard M, VOLINIA, Stefano, BUNDSCHUH, Ralf, FRANKHOUSER, David, BLOOMFIELD, Clara D, NICOLET, Deedra, METZELER, Klaus H, KOHLSCHMIDT, Jessica, MRÓZEK, Krzysztof, WU, Yue-Zhong, BUCCI, Donna

“…Molecular risk stratification of acute myeloid leukemia (AML) is largely based on genetic markers. However, epigenetic changes, including DNA methylation,…”
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Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study by BECKER, Heiko, MARCUCCI, Guido, POWELL, Bayard L, CARTER, Thomas H, KOLITZ, Jonathan E, WETZLER, Meir, CARROLL, Andrew J, BAER, Maria R, CALIGIURI, Michael A, LARSON, Richard A, BLOOMFIELD, Clara D, MAHARRY, Kati, RADMACHER, Michael D, MROZEK, Krzysztof, MARGESON, Dean, WHITMAN, Susan P, WU, Yue-Zhong, SCHWIND, Sebastian, PASCHKA, Peter

“…To analyze the prognostic significance of NPM1 mutations, and the associated gene- and microRNA-expression signatures in older patients with de novo,…”
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Outcomes in adolescent and young adult patients (16 to 30 years) compared to younger patients treated for high-risk B-lymphoblastic leukemia: report from Children’s Oncology Group Study AALL0232 by Burke, Michael J., Devidas, Meenakshi, Chen, Zhiguo, Salzer, Wanda L., Raetz, Elizabeth A., Rabin, Karen R., Heerema, Nyla A., Carroll, Andrew J., Gastier-Foster, Julie M., Borowitz, Michael J., Wood, Brent L., Winick, Naomi J., Carroll, William L., Hunger, Stephen P., Loh, Mignon L., Larsen, Eric C.

“…Adolescent and young adult (AYA) patients 16–30 years old with high-risk acute lymphoblastic leukemia (HR-ALL) have inferior outcomes compared to younger…”
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Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study by Paschka, Peter, Marcucci, Guido, Ruppert, Amy S., Mrózek, Krzysztof, Chen, Hankui, Kittles, Rick A., Vukosavljevic, Tamara, Perrotti, Danilo, Vardiman, James W., Carroll, Andrew J., Kolitz, Jonathan E., Larson, Richard A., Bloomfield, Clara D.

“…To analyze the prognostic impact of mutated KIT (mutKIT) in core-binding factor acute myeloid leukemia (AML) with inv(16)(p13q22) and t(8;21)(q22;q22)…”
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Intrachromosomal Amplification of Chromosome 21 Is Associated With Inferior Outcomes in Children With Acute Lymphoblastic Leukemia Treated in Contemporary Standard-Risk Children's Oncology Group Studies: A Report From the Children's Oncology Group by HEEREMA, Nyla A, CARROLL, Andrew J, WOOD, Brent L, WINICK, Naomi J, CARROLL, William L, HUNGER, Stephen P, RAETZ, Elizabeth A, DEVIDAS, Meenakshi, LOH, Mignon L, BOROWITZ, Michael J, GASTIER-FOSTER, Julie M, LARSEN, Eric C, MATTANO, Leonard A, MOLONEY, Kelly W, WILLMAN, Cheryl L

“…Five-year overall survival (OS) for children with B-cell precursor acute lymphoblastic leukemia (B-ALL) exceeds 90% with risk-adapted therapy. Age, initial WBC…”
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Microdeletion/microduplication of proximal 15q11.2 between BP1 and BP2: a susceptibility region for neurological dysfunction including developmental and language delay by Burnside, Rachel D., Pasion, Romela, Mikhail, Fady M., Carroll, Andrew J., Robin, Nathaniel H., Youngs, Erin L., Gadi, Inder K., Keitges, Elizabeth, Jaswaney, Vikram L., Papenhausen, Peter R., Potluri, Venkateswara R., Risheg, Hiba, Rush, Brooke, Smith, Janice L., Schwartz, Stuart, Tepperberg, James H., Butler, Merlin G.

“…The proximal long arm of chromosome 15 has segmental duplications located at breakpoints BP1–BP5 that mediate the generation of NAHR-related microdeletions and…”
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MicroRNA Expression in Cytogenetically Normal Acute Myeloid Leukemia by Marcucci, Guido, Radmacher, Michael D, Maharry, Kati, Mrózek, Krzysztof, Ruppert, Amy S, Paschka, Peter, Vukosavljevic, Tamara, Whitman, Susan P, Baldus, Claudia D, Langer, Christian, Liu, Chang-Gong, Carroll, Andrew J, Powell, Bayard L, Garzon, Ramiro, Croce, Carlo M, Kolitz, Jonathan E, Caligiuri, Michael A, Larson, Richard A, Bloomfield, Clara D

“…This study outlines the development of a microRNA signature in patients with cytogenetically normal acute myeloid leukemia (AML) with high-risk molecular…”
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Favorable Trisomies and ETV6-RUNX1 Predict Cure in Low-Risk B-Cell Acute Lymphoblastic Leukemia: Results From Children's Oncology Group Trial AALL0331 by Mattano, Jr, Leonard A, Devidas, Meenakshi, Maloney, Kelly W, Wang, Cindy, Friedmann, Alison M, Buckley, Patrick, Borowitz, Michael J, Carroll, Andrew J, Gastier-Foster, Julie M, Heerema, Nyla A, Kadan-Lottick, Nina S, Matloub, Yousif H, Marshall, David T, Stork, Linda C, Loh, Mignon L, Raetz, Elizabeth A, Wood, Brent L, Hunger, Stephen P, Carroll, William L, Winick, Naomi J

“…Children's Oncology Group (COG) AALL0331 tested whether pegaspargase intensification on a low-intensity chemotherapy backbone would improve the continuous…”
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