Search Results - "CARRIO, M. Mar"
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Localization of Chaperones DnaK and GroEL in Bacterial Inclusion Bodies
Published in Journal of Bacteriology (01-05-2005)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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2
Protein aggregation in recombinant bacteria: biological role of inclusion bodies
Published in Biotechnology letters (01-09-2003)“…Protein aggregation is an ordinary consequence of thermal stress. In recombinant bacteria, the over-expression of plasmid-encoded genes triggers transcription…”
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3
Folding of a misfolding-prone β-galactosidase in absence of DnaK
Published in Biotechnology and bioengineering (30-06-2005)“…In absence of chaperone DnaK, bacterially produced misfolding‐prone proteins aggregate into large inclusion bodies, but still a significant part of these…”
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4
Bacterial inclusion bodies are cytotoxic in vivo in absence of functional chaperones DnaK or GroEL
Published in Journal of biotechnology (10-09-2005)“…Cytotoxicity of cytoplasmic bacterial inclusion bodies has been explored in vivo in cells producing a model, misfolding-prone β-galactosidase fusion protein…”
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5
Role of molecular chaperones in inclusion body formation
Published in FEBS letters (27-02-2003)“…Protein misfolding and aggregation are linked to several degenerative diseases and are responsible for the formation of bacterial inclusion bodies. Roles of…”
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The impact of DnaKJ overexpression on recombinant protein solubility results from antagonistic effects on the control of protein quality
Published in Biotechnology letters (01-04-2004)“…We have produced increasing levels of DnaK and its co-chaperone DnaJ along with the model VP1LAC misfolding-prone protein, to explore the role of DnaK on the…”
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7
Protein aggregation as bacterial inclusion bodies is reversible
Published in FEBS letters (26-01-2001)“…Inclusion bodies are refractile, intracellular protein aggregates usually observed in bacteria upon targeted gene overexpression. Since their occurrence has a…”
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8
Fine architecture of bacterial inclusion bodies
Published in FEBS letters (07-04-2000)“…The molecular organisation of protein aggregates, formed under physiological conditions, has been explored by in vitro trypsin treatment and electron…”
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9
In Situ Proteolytic Digestion of Inclusion Body Polypeptides Occurs as a Cascade Process
Published in Biochemical and biophysical research communications (30-03-2001)“…Misfolded proteins undergo a preferent degradation ruled by the housekeeping bacterial proteolytic system, but upon precipitation as inclusion bodies their…”
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