Search Results - "CARRATU, M. R"

Rat embryo exposure to all-trans retinoic acid results in long-term cognitive deficits by Borracci, P, Carratù, M R

“…The present study examines in particular associative learning and aversive memory abilities in adult Sprague Dawley rats exposed to all-trans retinoic acid…”
Get more information

Therapeutic targeting of the mTOR‐signalling pathway in cancer: benefits and limitations by Moschetta, M, Reale, A, Marasco, C, Vacca, A, Carratù, M R

“…The mammalian target of rapamycin (mTOR) plays an important role in the regulation of protein translation, cell growth and metabolism. The mTOR protein forms…”
Get full text

Retinoids: novel immunomodulators and tumour‐suppressive agents? by Carratù, MR, Marasco, C, Mangialardi, G, Vacca, A

“…Retinoids play important roles in the transcriptional activity of normal, degenerative and tumour cells. Retinoid analogues may be promising therapeutic agents…”
Get full text

Mapping ligand binding pockets in chloride ClC‐1 channels through an integrated in silico and experimental approach using anthracene‐9‐carboxylic acid and niflumic acid by Altamura, C, Mangiatordi, G F, Nicolotti, O, Sahbani, D, Farinato, A, Leonetti, F, Carratù, M R, Conte, D, Desaphy, J‐F, Imbrici, P

“…Background and Purpose Although chloride channels are involved in several physiological processes and acquired diseases, the availability of compounds…”
Get full text

Long-term effects on cortical glutamate release induced by prenatal exposure to the cannabinoid receptor agonist ( r)-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinyl-methyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone: an in vivo microdialysis study in the awake rat by Antonelli, T, Tanganelli, S, Tomasini, M.C, Finetti, S, Trabace, L, Steardo, L, Sabino, V, Carratu, M.R, Cuomo, V, Ferraro, L

“…The aim of the present in vivo microdialysis study was to investigate whether prenatal exposure to the CB 1 receptor agonist WIN55,212–2 mesylate (WIN; (…”
Get full text

Ineffectiveness of activated carbon in reducing the alteration of sphingolipid metabolism in rats exposed to fumonisin-contaminated diets by Solfrizzo, M, Carratu, M.R, Avantaggiato, G, Galvano, F, Pietri, A, Visconti, A

“…Sphinganine/sphingosine (SA/SO) ratio, a biomarker of fumonisin exposure, has been measured in urine, kidney and liver of male Wistar rats exposed to…”
Get full text

Are retinoids a promise for Alzheimer's disease management? by Carratù, M R, Marasco, C, Signorile, A, Scuderi, C, Steardo, L

“…Retinoids regulate several physiological and pathological processes through the interaction with nuclear receptors. Retinoid-associated signaling which plays…”
Get more information

Prenatal exposure to low concentrations of carbon monoxide alters habituation and non-spatial working memory in rat offspring by Giustino, Arcangela, Cagiano, Raffaele, Carratù, Maria Rosaria, Cassano, Tommaso, Tattoli, Maria, Cuomo, Vincenzo

“…Inhalation of low concentrations (75 and 150 ppm) of carbon monoxide (CO) by pregnant rats from days 0 to 20 of gestation leads to alterations in habituation…”
Get full text

Acute exposure to methylmercury at two developmental windows: Focus on neurobehavioral and neurochemical effects in rat offspring by Carratù, M.R., Borracci, P., Coluccia, A., Giustino, A., Renna, G., Tomasini, M.C., Raisi, E., Antonelli, T., Cuomo, V., Mazzoni, E., Ferraro, L.

“…The neurobehavioral and neurochemical effects produced by prenatal methylmercury exposure (8 mg/kg, gestational-days 8 or 15), were investigated in rats. On…”
Get full text

Neurofunctional effects of developmental sodium fluoride exposure in rats by Bera, I, Sabatini, R, Auteri, P, Flace, P, Sisto, G, Montagnani, M, Potenza, M A, Marasciulo, F L, Carratu, M R, Coluccia, A, Borracci, P, Tarullo, A, Cagiano, R

“…Contrasting studies on the toxic effects of sodium fluoride (NaF) during developmental stages of Wistar rats, lead us to investigate the neurofunctional…”
Get full text

Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 and carbon monoxide reduces extracellular glutamate levels in primary rat cerebral cortex cell cultures by Antonelli, T., Tomasini, M.C., Tattoli, M., Cassano, T., Finetti, S., Mazzoni, E., Trabace, L., Carratù, M.R., Cuomo, V., Tanganelli, S., Ferraro, L.

“…The effects of prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 (0.5 mg/kg s.c.), alone or in combination with carbon monoxide, on…”
Get full text

Alterations in the ontogeny of rat pup ultrasonic vocalization produced by prenatal exposure to nitrogen dioxide by DI GIOVANNI, V, CAGIANO, R, CARRATU, M. R, DE SALVIA, M. A, GIUSTINO, A, CUOMO, V

“…Wistar female rats were exposed to low concentrations of nitrogen dioxide, NO2 (1.5 and 3 ppm) from day 0 to day 20 of pregnancy. The results show that…”
Get full text

Smoking during pregnancy: a risk factor for peripheral neuropathy? by Carratù, M R, Coluccia, A, Borracci, P, Fasano, A, Riccio, P, Cuomo, V

“…Studies dealing with the outcomes of developmental carbon monoxide (CO) exposure on myelination in rat offspring are reviewed. Prenatal CO exposure from…”
Get more information

Potassium channel modulation by the pseudopeptide ochratoxin A in rat nerve fibers by Carratú, Maria-Rosaria, Belmadani, Abdelhak, Cuomo, Vincenzo, Creppy, Edmond Ekué

“…Ochratoxin A (OTA), a naturally occurring mycotoxin produced by Aspergillus and Penicillium genera, blocks anion conductance in Madin‐Darby canine kidney…”
Get full text

Mechanism of action of a structural analog of alphaxalone on myelinated nerve fibre by Benoit, E, Carratù, M R, Mitolo-Chieppa, D

“…The action of alphadolone acetate (0.05-5 mM), a steroid anaesthetic and structural analog of alphaxalone, was investigated on frog myelinated axons under…”
Get more information

Recent advances in the study of epigenetic effects induced by the phycotoxin okadaic acid by Creppy, Edmond Ekué, Traoré, Adama, Baudrimont, Isabelle, Cascante, Marta, Carratú, Maria-Rosaria

“…Okadaic acid (OA) is a phycotoxin produced by dinoflagellates. It accumulates in the digestive tracts of shellfish causing diarrhetic shellfish poisoning (DSP)…”
Get full text

Prenatal exposure to carbon monoxide affects postnatal cellular electrophysiological maturation of the rat heart: A potential substrate for arrhythmogenesis in infancy by SARTIANI, Laura, CERBAI, Elisabetta, LONARDO, Giuseppe, DEPAOLI, Petra, TATTOLI, Maria, CAGIANO, Raffaele, CARRATU, Maria Rosaria, CUOMO, Vincenzo, MUGELLI, Alessandro

“…Maternal smoking is an independent risk factor for sudden infant death syndrome (SIDS). Carbon monoxide (CO) is a major component of smoke. No information is…”
Get full text

INHIBITION OF IONIC CURRENTS IN FROG NODE OF RANVIER TREATED WITH NALOXONE by Carratu, M R, Mitolo-Chieppa, D

“…1 Myelinated nerve fibres of frog sciatic nerve were investigated under current and voltage clamp conditions. In the presence of 68 μM external naloxone, the…”
Get full text

Prenatal exposure model simulating CO inhalation in human cigarette smokers: sphingomyelin alterations in the rat sciatic nerve by Carratù, M.R, Cagiano, R, Tattoli, M, Trabace, L, Borracci, P, Cuomo, V

“…Prenatal exposure to low concentrations of carbon monoxide (CO, 150 ppm) causes long-term alterations in sphingomyelin (SM) homeostasis in peripheral nervous…”
Get full text

Prenatal exposure to low levels of carbon monoxide alters sciatic nerve myelination in rat offspring by Carratù, M.R., Cagiano, R., Desantis, S., Labate, M., Tattoli, M., Trabace, L., Cuomo, V.

“…Prenatal exposure to low concentrations of carbon monoxide (CO, 75 and 150 ppm from day 0 to day 20 of gestation), resulting in maternal blood HbCO…”
Get full text