Search Results - "CARRÃO, Daniel Blascke"
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Metabolism studies of chiral pesticides: A critical review
Published in Journal of pharmaceutical and biomedical analysis (05-01-2018)“…•The stereoselective metabolism of chiral pesticides is important for risk assessment.•Stereoselective results were found on metabolism of chiral…”
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A Review of Analytical Methods for Codeine Determination
Published in Molecules (Basel, Switzerland) (04-02-2021)“…Codeine is derived from morphine, an opioid analgesic, and has weaker analgesic and sedative effects than the parent molecule. This weak opioid is commonly…”
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In vitro inhibition of human CYP2D6 by the chiral pesticide fipronil and its metabolite fipronil sulfone: Prediction of pesticide-drug interactions
Published in Toxicology letters (01-10-2019)“…[Display omitted] •Rac-fipronil, S-fipronil, R-fipronil and fipronil sulfone inhibited CYP2D6.•Both fipronil and its metabolite are competitive inhibitors of…”
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Emerging applications of paper-based analytical devices for drug analysis: A review
Published in Analytica chimica acta (15-06-2020)“…The use of paper microfluidics to perform chemical measurements for various analytical applications has gained interest over the last decade. One of the…”
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Prediction of seriniquinone-drug interactions by in vitro inhibition of human cytochrome P450 enzymes
Published in Toxicology in vitro (01-06-2020)“…Seriniquinone is a secondary metabolite isolated from a rare marine bacterium of the genus Serinicoccus. This natural quinone is highlighted for its selective…”
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Phenolic and flavonoid content and in vitro inhibitory effect of some Amazonian fruit juices on CYP3A4 activity
Published in Acta amazonica (01-04-2022)“…ABSTRACT Many foods interact with drugs and may cause changes in the pharmacological effects of the co-administered therapeutic agent. The enzyme CYP3A4, which…”
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Enantioseparation of pesticides: A critical review
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-01-2020)“…The potential of chiral pesticides to exhibit stereoselective behavior in regards to activity, toxicity, degradation, bioaccumulation, and/or metabolism has…”
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Evaluation of the enantioselective in vitro metabolism of the chiral pesticide fipronil employing a human model: Risk assessment through in vitro-in vivo correlation and prediction of toxicokinetic parameters
Published in Food and chemical toxicology (01-01-2019)“…The chiral pesticide fipronil is employed as a racemic mixture to control pests. Although there are no enantioselective differences in the fipronil enantiomer…”
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Enantioselective inhibition of human CYP2C19 by the chiral pesticide ethofumesate: Prediction of pesticide-drug interactions in humans
Published in Chemico-biological interactions (25-08-2021)“…Ethofumesate is a chiral herbicide that may display enantioselective behavior in humans. For this reason, the enantioselective potential of ethofumesate and…”
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In vitro enantioselective inhibition of the main human CYP450 enzymes involved in drug metabolism by the chiral pesticide tebuconazole
Published in Toxicology letters (15-10-2021)“…•Rac-Tebuconazole and its isolated enantiomers inhibited CYP3A4/5, 2C9, 2C19 and 2D6.•Inhibition was enantioselective for CYP2C9, CYP2C19 and…”
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Risk assessment of the chiral pesticide fenamiphos in a human model: Cytochrome P450 phenotyping and inhibition studies
Published in Food and chemical toxicology (01-12-2020)“…Fenamiphos (FS) is a chiral organophosphate pesticide that is used to control nematodes in several crops. Enantioselective differences may be observed in FS…”
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Paenibacillus polymyxa Associated with the Stingless Bee Melipona scutellaris Produces Antimicrobial Compounds against Entomopathogens
Published in Journal of chemical ecology (01-12-2018)“…Social insects are frequently observed in symbiotic association with bacteria that produce antimicrobial natural products as a defense mechanism. There is a…”
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Method validation and nanoparticle characterization assays for an innovative amphothericin B formulation to reach increased stability and safety in infectious diseases
Published in Journal of pharmaceutical and biomedical analysis (25-10-2017)“…[Display omitted] •NLC-AmB characterizations employing DLS, AFM, FT-IR and DSC/TGA demonstrated the nanosized scale of the DDS and evidenced the mechanical…”
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A three phase hollow fiber liquid-phase microextraction for quantification of lamotrigine in plasma of epileptic patients by capillary electrophoresis
Published in Electrophoresis (01-10-2016)“…A three phase hollow fiber liquid‐phase microextraction technique combined with capillary electrophoresis was developed to quantify lamotrigine (LTG) in plasma…”
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In Vitro Metabolism of Artepillin C by Rat and Human Liver Microsomes
Published in Planta medica (01-05-2017)“…Artepillin C, a natural product present in the Brazilian green propolis, has several biological properties. Among these properties, the antitumor action of…”
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Assessment of the stereoselective fungal biotransformation of albendazole and its analysis by HPLC in polar organic mode
Published in Journal of pharmaceutical and biomedical analysis (05-03-2012)“…A high-performance liquid chromatographic method using polar organic mode was developed to analyze albendazole (ABZ), albendazole sulfone (ABZSO 2) and the…”
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Enantioselective in vitro metabolism and in vitro-in vivo correlation of the herbicide ethofumesate in a human model
Published in Journal of pharmaceutical and biomedical analysis (05-08-2020)“…[Display omitted] •Ethofumesate is metabolized by human CYP2C19 and CYP3A4 into ethofumesate-2-hydroxy.•(+)-ETO is metabolized by CYP2C19 and CYP3A4.•(–)-ETO…”
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