Search Results - "CARR, T. J"

Metal control of selectivity in acetate-assisted C–H bond activation: an experimental and computational study of heterocyclic, vinylic and phenylic C(sp 2 )–H bonds at Ir and Rh by Carr, Kevin J. T., Davies, David L., Macgregor, Stuart A., Singh, Kuldip, Villa-Marcos, Barbara

“…Acetate-assisted C(sp 2 )–H bond activation at [MCl 2 Cp*] 2 (M = Ir, Rh) has been studied for a series of N -alkyl imines, i PrNCHR, (R = N…”
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Aggressive Treatment for Postcardiac Transplant Lymphoproliferation by Swinnen, Lode J., Mullen, G.Martin, Carr, Thomas J., Costanzo, Maria R., Fisher, Richard I.

“…Posttransplant lymphoprolKerative disorder (PTLD) is a frequently fatal complication of organ transplantation, occurring in 2% to 6% of cardiac recipients…”
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An In Vivo Proton Magnetic Resonance Spectroscopy Study of Schizophrenia Patients by Stanley, Jeff A., Williamson, Peter C., Drost, Dick J., Rylett, R. Jane, Carr, Tom J., Malla, Ashok, Thompson, R. Terry

“…The level of the 1H metabolites in the left dorsolateral prefrontal region of schizophrenia patients at different stages of illness were measured in vivo using…”
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A short echo proton magnetic resonance spectroscopy study of the left mesial-temporal lobe in first-onset schizophrenic patients by Bartha, Robert, Al-Semaan, Yousef M, Williamson, Peter C, Drost, Dick J, Malla, Ashok K, Carr, Tom J, Densmore, Maria, Canaran, Gita, Neufeld, Richard W.J

“…Background: Past 1H magnetic resonance spectroscopy (MRS) studies of the temporal lobe in schizophrenic patients have shown decreased levels of…”
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Inhibition of Human Immunodeficiency Virus 1 Protease in vitro: Rational Design of Substrate Analogue Inhibitors by Dreyer, Geoffrey B., Metcalf, Brian W., Tomaszek, Thaddeus A., Carr, Thomas J., Chandler, Arthur C., Hyland, Lawrence, Fakhoury, Stephen A., Magaard, Victoria W., Moore, Michael L., Strickler, James E., Debouck, Christine, Meek, Thomas D.

“…Inhibitors of the protease from human immunodeficiency virus 1 (HIV-1) were designed, synthesized, and kinetically characterized. Analogues of a heptapeptide…”
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Use of Papain as a Model for the Structure-Based Design of Cathepsin K Inhibitors:  Crystal Structures of Two Papain−Inhibitor Complexes Demonstrate Binding to S‘-Subsites by LaLonde, Judith M, Zhao, Baoguang, Smith, Ward W, Janson, Cheryl A, DesJarlais, Renee L, Tomaszek, Thaddeus A, Carr, Thomas J, Thompson, Scott K, Oh, Hye-Ja, Yamashita, Dennis S, Veber, Daniel F, Abdel-Meguid, Sherin S

“…Papain has been used as a surrogate enzyme in a drug design effort to obtain potent and selective inhibitors of cathepsin K, a new member of the papain…”
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BCL-2 But Not Its Epstein-Barr Virus-Encoded Homologue, BHRF1, Is Commonly Expressed in Posttransplantation Lymphoproliferative Disorders by Murray, Paul G., Swinnen, Lode J., Constandinou, Christothea M., Pyle, Joseph M., Carr, Thomas J., Hardwick, J.Marie, Ambinder, Richard F.

“…Posttransplantation lymphoproliferative disease (PTLD) is virtually always associated with Epstein-Barr virus (EBV) infection. BCL-2 and other proteins that…”
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Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, x-ray crystallography, and infected T-cell assays by Dreyer, Geoffrey B, Lambert, Dennis M, Meek, Thomas D, Carr, Thomas J, Tomaszek, Thaddeus A, Fernandez, Annabellee V, Bartus, Henry, Cacciavillani, Emilio, Hassell, Anne M

“…Analogues of peptides ranging in size from three to six amino acids and containing the hydroxyethylene dipeptide isosteres Phe psi Gly, Phe psi Ala, Phe psi…”
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Establishing and maintaining international collaborative research teams: an autobiographical insight by Carr, T J, Van der walt, C, Watson, F, Linda, N

“…Despite the growing impetus for international collaborative research teams (ICRT), there are relatively few resources available to guide and support…”
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Magnetic resonance imaging volumetric and phosphorus 31 magnetic resonance spectroscopy measurements in schizophrenia by HINSBERGER, A. D, WILLIAMSON, P. C, CARR, T. J, STANLEY, J. A, DROST, D. J, DENSMORE, M, MACFABE, G. C, MONTEMURRO, D

“…The purpose of this study was to examine the relationship between phosphorus magnetic resonance spectroscopy (31P MRS) parameters and left prefrontal volumes…”
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Proton magnetic resonance imaging to stage activity of interstitial lung disease by McFadden, R G, Carr, T J, Wood, T E

“…Patients with active interstitial lung disease (ILD) are often treated with high-dose corticosteroids, although such therapy is not universally effective and…”
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Thoracic magnetic resonance imaging in the evaluation of HIV-1/AIDS pneumonitis by McFadden, R G, Carr, T J, Mackie, I D

“…Magnetic resonance imaging of the thorax was performed on ten occasions in eight HIV-positive patients with a clinical picture suggestive of Pneumocystis…”
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Magnetic resonance imaging to diagnose intralobar pulmonary sequestration by Oliphant, L, McFadden, R G, Carr, T J, Mackenzie, D A

“…Confirmation of the diagnosis of intralobar pulmonary sequestration has usually required angiographic demonstration of the systemic arterial supply. We report…”
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Information for the driver by Carr, J T

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Structure and Design of Potent and Selective Cathepsin K Inhibitors by Yamashita, Dennis S., Smith, Ward W., Zhao, Baoguang, Janson, Cheryl A., Tomaszek, Thaddeus A., Bossard, Mary J., Levy, Mark A., Oh, Hye-Ja, Carr, Thomas J., Thompson, Scott K., Ijames, Carl F., Carr, Steven A., McQueney, Michael, D'Alessio, Karla J., Amegadzie, Bernard Y., Hanning, Charles R., Abdel-Meguid, Sherin, DesJarlais, Renee L., Gleason, John G., Veber, Daniel F.

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Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy by Bartha, R, Williamson, P C, Drost, D J, Malla, A, Carr, T J, Cortese, L, Canaran, G, Rylett, R J, Neufeld, R W

“…Positron emission tomographic and postmortem studies comparing schizophrenic patients with healthy control subjects have found medial prefrontal cortical and…”
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An in vivo study of the prefrontal cortex of schizophrenic patients at different stages of illness via phosphorus magnetic resonance spectroscopy by Stanley, J A, Williamson, P C, Drost, D J, Carr, T J, Rylett, R J, Malla, A, Thompson, R T

“…In this study, phospholipid metabolism of cell membranes, high-energy phosphate metabolism, and intracellular free magnesium concentration in the prefrontal…”
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Magnetic resonance imaging for detecting lesions of multiple sclerosis: comparison with computed tomography and clinical assessment by Reese, L, Carr, T J, Nicholson, R L, Lepp, E K

“…Eighty-two patients with known or suspected multiple sclerosis (MS) were examined by means of magnetic resonance imaging (MRI) with a 0.15-T resistive scanner…”
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Potent dipeptidylketone inhibitors of the cysteine protease cathepsin K by Marquis, Robert W, Ru, Yu, Yamashita, Dennis S, Oh, Hye-Ja, Yen, Jack, Thompson, Scott K, Carr, Thomas J, Levy, Mark A, Tomaszek, Thaddeus A, Ijames, Carl F, Smith, Ward W, Zhao, Baoguang, Janson, Cheryl A, Abdel-Meguid, Sherin S, D'Alessio, Karla J, McQueney, M.S, Veber, Daniel F

“…Cathepsin K (EC 3.4.22.38) is a cysteine protease of the papain superfamily which is selectively expressed within the osteoclast. Several lines of evidence…”
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An Orally Bioavailable HIV-1 Protease Inhibitor Containing an Imidazole-Derived Peptide Bond Replacement: Crystallographic and Pharmacokinetic Analysis by Abdel-Meguid, Sherin S, Metcalf, Brian W, Carr, Thomas J, Demarsh, Peter, DesJarlais, Renee L, Fisher, Seth, Green, David W, Ivanoff, Lucinda, Lambert, Dennis M

“…(2R,4S,5S,1'S)-2-Phenylmethyl-4-hydroxy-5-(tert-butoxycarbonyl) amino-6-phenylhexanoyl-N-(1'-imidazo-2-yl)-2'-methylpropanamide (compound 2) is a tripeptide…”
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