Search Results - "CARPER, D"

Expression analysis of human pterygium shows a predominance of conjunctival and limbal markers and genes associated with cell migration by Jaworski, C J, Aryankalayil-John, M, Campos, M M, Fariss, R N, Rowsey, J, Agarwalla, N, Reid, T W, Dushku, N, Cox, C A, Carper, D, Wistow, G

“…Pterygium is a vision-impairing fibrovascular lesion that grows across the corneal surface and is associated with sunlight exposure. To increase our…”
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Oxidative stress induces differential gene expression in a human lens epithelial cell line by Carper, DA, Sun, JK, Iwata, T, Zigler, JS, Jr, Ibaraki, N, Lin, LR, Reddy, V

“…To identify differentially expressed genes in a human lens epithelial cell line exposed to oxidative stress. Reverse transcriptase-polymerase chain reaction…”
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Molecular Modeling of the Aldose Reductase-Inhibitor Complex Based on the X-ray Crystal Structure and Studies with Single-Site-Directed Mutants by Singh, Suresh B, Malamas, Michael S, Hohman, Thomas C, Nilakantan, Ramaswamy, Carper, Deborah A, Kitchen, Douglas

“…Aldose reductase (AR) has been implicated in the etiology of the secondary complications of diabetes. This enzyme catalyzes the reduction of glucose to…”
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Up-regulation of osteonectin/SPARC in age-related cataractous human lens epithelia by Kantorow, M, Horwitz, J, Carper, D

“…To characterize gene expression patterns between epithelia isolated from cataractous and normal human lenses. Reverse transcriptase differential display was…”
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Preparation of oriented PbTiO3 thin films using a spin-on sol-gel process by CARPER, M. D, PHULE, P. P

“…A novel sol-gel process for the preparation of grain-oriented thin films of PbTiO3 is reported. Using a moisture tolerant molecularly modified titanium…”
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Differential Gene Expression in Male and Female Rat Lenses Undergoing Cataract Induction by Transforming Growth Factor-β (TGF-β) by SUN, JENNIFER K., IWATA, TAKESHI, ZIGLER JR, J.SAMUEL, CARPER, DEBORAH A.

“…Epidemiologic studies in humans as well as immunohistologic studies in animals have demonstrated significant sex differences in the propensity to develop…”
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Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis by Serhan, Charles N, Chew, Emily Y, Hong, Song, Carper, Deborah, Salem, Norman, Chen, Jing, Connor, Kip M, Aderman, Christopher M, Higuchi, Akiko, Smith, Lois E H, Majchrzak, Sharon, Pravda, Elke A, Kang, Jing X, Hellstrom, Ann, Lofqvist, Chatarina, SanGiovanni, John Paul

“…Many sight-threatening diseases have two critical phases, vessel loss followed by hypoxia-driven destructive neovascularization. These diseases include…”
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Na,K-ATPase response to osmotic stress in primary dog lens epithelial cells by Old, SE, Carper, DA, Hohman, TC

“…Na,K-ATPase activity increases in lens cells exposed to hypertonic stress. To test whether the increase in activity involves stimulation of Na,K-ATPase…”
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A superfamily of NADPH-dependent reductases in eukaryotes and prokaryotes by Carper, D A, Wistow, G, Nishimura, C, Graham, C, Watanabe, K, Fujii, Y, Hayashi, H, Hayaishi, O

“…Aldose reductase (AR) is implicated in some of the disabling complications of diabetes, including neuropathy, retinopathy and cataracts. Our studies are aimed…”
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Characterization of the mouse aldose reductase gene and promoter in a lens epithelial cell line by McGowan, M H, Iwata, T, Carper, D A

“…To clone and characterize the mouse aldose reductase (AR) gene and evaluate the functional promoter under basal and hypertonic conditions in mouse lens…”
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Cloning and expression of human aldose reductase by NISHIMURA, C, MATSUURA, Y, KOKAI, Y, AKERA, T, CARPER, D, MORJANA, N, LYONS, C, FLYNN, T. G

“…The complete amino acid sequence of human retina and muscle aldose reductase was determined by nucleotide analysis of cDNA clones isolated using synthetic…”
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Human sorbitol dehydrogenase gene. cDNA sequence and expression by Iwata, T, Carper, D

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Na+, K+-ATPase inhibitors down-regulate gene expression of the intracellular signaling protein 14-3-3 in rat lens by McGowan, M H, Russell, P, Carper, D A, Lichtstein, D

“…To identify genes that are differentially expressed by Na+, K+-ATPase inhibitors, we used the differential display technique to compare mRNA expression…”
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Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites by El-Kabbani, O, Old, S E, Ginell, S L, Carper, D A

“…To identify the structural features responsible for the differences in coenzyme and inhibitor specificities of aldose and aldehyde reductases. The crystal…”
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Alteration of a developmentally regulated, heat-stable polypeptide in the lens of the Philly mouse. Implications for cataract formation by Nakamura, M, Russell, P, Carper, D A, Inana, G, Kinoshita, J H

“…The beta-crystallin basic principal polypeptide (beta Bp) appears to be altered in the lens of the Philly mouse and may be the main defect in this hereditary…”
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Phase Separation in Lens Cytoplasm is Genetically Linked to Cataract Formation in the Philly Mouse by Clark, John I., Carper, Deborah

“…The variation of the phase-separation temperature, Tc, in lenses was studied during the postnatal development of three genetically different mouse strains: (i)…”
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Prion protein expression in mammalian lenses by Frederikse, Peter H., Zigler, J. Samuel, Farnsworth, Patricia N., Carper, Deborah A.

“…Purpose. Aging and oxidative stress resulting from over-expression of Alzheimer precursor protein (ßAPP) have been studied as important factors contributing to…”
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In vitro Expression of Rat Lens Aldose Reductase in Escherichia coli by Old, Susan E., Sato, Sanai, Kador, Peter F., Carper, Deborah A.

“…Aldose reductase (alditol:NADP+oxidore ductase, EC 1.1.1.21), an enzyme that converts glucose to sorbitol, the first step of the polyol pathway, has been…”
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Studies on the inhibitor-binding site of porcine aldehyde reductase: Crystal structure of the holoenzyme-inhibitor ternary complex by El-Kabbani, Ossama, Carper, Deborah A., McGowan, Michelle H., Devedjiev, Yancho, Rees-Milton, Karen J., Flynn, T. Geoffrey

“…Aldehyde reductase is an enzyme capable of metabolizing a wide variety of aldehydes to their corresponding alcohols. The tertiary structures of aldehyde…”
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Structural organization of the human sorbitol dehydrogenase gene (SORD) by Iwata, Takeshi, Popescu, Nicholas C., Zimonjic, Drazen B., Karlsson, Christina, Höög, Jan-olov, Vaca, Geraldo, Rodriguez, Ignacio R., Carper, Deborah

“…The primary structure of human sorbitol dehydrogenase (SORD) was determined by cDNA and genomic cloning. The nucleotide sequence of the mRNA covers 2471 bp…”
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