Search Results - "CARNAUD, C"
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S.13.03 Immunotherapy in prion diseases
Published in European neuropsychopharmacology (01-10-2012)Get full text
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Protection Against Diabetes and Improved NK/NKT Cell Performance in NOD.NK1.1 Mice Congenic at the NK Complex
Published in The Journal of immunology (1950) (15-02-2001)“…The NK1.1 cell surface receptor, which belongs to the NKR-P1 gene cluster, has been bred onto nonobese diabetic (NOD) mice for two purposes. The first was to…”
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Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates: requirement for both L3T4+ and Lyt-2+ T cells
Published in The Journal of experimental medicine (01-10-1987)“…We have developed a model of syngeneic adoptive transfer for type I diabetes mellitus of NOD mice. This model consists in injecting spleen cells from diabetic…”
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The contribution of animal models to the understanding of the pathogenesis of type 1 diabetes
Published in Brazilian journal of medical and biological research (01-08-1995)“…The autoimmune nature of insulin-dependent diabetes mellitus (type 1 diabetes) has been definitively established during the past ten years only, owing…”
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Genetic control of giant perivascular space formation in the thymus of NOD mice
Published in Diabetes (New York, N.Y.) (01-11-1996)“…Genetic control of giant perivascular space formation in the thymus of NOD mice. E Colomb , W Savino , L Wicker , L Peterson , M Dardenne and C Carnaud Hôpital…”
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Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and granzyme A in the intra-islet infiltrates
Published in Diabetes (New York, N.Y.) (01-01-1995)“…Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and…”
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Characterization of the extracellular matrix-containing giant perivascular spaces in the NOD mouse thymus
Published in Diabetes (New York, N.Y.) (01-01-1993)“…Characterization of the extracellular matrix-containing giant perivascular spaces in the NOD mouse thymus. W Savino , C Carnaud , J J Luan , J F Bach and M…”
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Inhibition of submandibular and lacrimal gland infiltration in nonobese diabetic mice by transgenic expression of soluble TNF-receptor p55
Published in The Journal of clinical investigation (15-08-1996)“…Besides a prominent mononuclear cell infiltration of the islets of Langerhans, nonobese diabetic (NOD) mice also show massive cellular infiltrates of the…”
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Prevention of Diabetes in Nonobese Diabetic Mice by Anti-I-A Monoclonal Antibodies: Transfer of Protection by Splenic T Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1988)“…The nonobese diabetic (NOD) mouse has been developed as a model for insulin-dependent diabetes. One gene required for the development of diabetes is associated…”
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Treatment with neutralizing antibodies specific for IL-1beta prevents cyclophosphamide-induced diabetes in nonobese diabetic mice
Published in Diabetes (New York, N.Y.) (01-06-1997)“…Treatment with neutralizing antibodies specific for IL-1beta prevents cyclophosphamide-induced diabetes in nonobese diabetic mice. C Cailleau , A Diu-Hercend ,…”
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Adoptive T cell transfer of autoimmune nonobese diabetic mouse diabetes does not require recruitment of host B lymphocytes
Published in The Journal of immunology (1950) (15-10-1988)“…The autoimmune nonobese diabetic mouse, a model of human juvenile type I diabetes mellitus, exhibits features of both B and T cell autoreactivity against…”
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Cutting Edge: Cross-Talk Between Cells of the Innate Immune System: NKT Cells Rapidly Activate NK Cells
Published in The Journal of immunology (1950) (01-11-1999)“…alpha-Galactosylceramide (alpha-GalCer) is a glycolipid with potent antitumor properties that binds to CD1d molecules and activates mouse Valpha14 and human…”
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Impairment of NK Cell Function by NKG2D Modulation in NOD Mice
Published in Immunity (Cambridge, Mass.) (2003)“…Nonobese diabetic (NOD) mice, a model of insulin-dependent diabetes mellitus, have a defect in natural killer (NK) cell-mediated functions. Here we show…”
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Overexpression of Natural Killer T Cells Protects V alpha 14-J alpha 281 Transgenic Nonobese Diabetic Mice against Diabetes
Published in The Journal of experimental medicine (16-11-1998)“…Progression to destructive insulitis in nonobese diabetic (NOD) mice is linked to the failure of regulatory cells, possibly involving T helper type 2 (Th2)…”
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Transplantation Tolerance Correlates with High Levels of T- and B-Lymphocyte Activity
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1989)“…Mice tolerized (treated to make them tolerant) at birth to transplantation antigens by injection of semi-allogeneic cells contain very high numbers of…”
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Host humoral and cellular immune mechanisms in the continued suppression of friend erythroleukemia metastases after interferon α/β treatment in mice
Published in The Journal of experimental medicine (01-05-1991)“…DBA/2 mice were injected intravenously with 2 x 10(6) 3C18 Friend erythroleukemia cells (FLC), a cell line resistant to interferon alpha/beta (IFN-alpha/beta)…”
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NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen
Published in The Journal of immunology (1950) (15-03-2001)“…The onset of autoimmune diabetes is related to defective immune regulation. Recent studies have shown that NK T cells are deficient in number and function in…”
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Damage control, rather than unresponsiveness, effected by protective DX5 + T cells in autoimmune diabetes
Published in Nature immunology (01-12-2001)“…The progression of autoimmune diabetes is regulated. We examined here the cellular controls exerted on disease that developed in the BDC2.5 T cell…”
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NK T Cell-Induced Protection Against Diabetes in Vα14-Jα281 Transgenic Nonobese Diabetic Mice Is Associated with a Th2 Shift Circumscribed Regionally to the Islets and Functionally to Islet Autoantigen
Published in The Journal of immunology (1950) (15-03-2001)“…The onset of autoimmune diabetes is related to defective immune regulation. Recent studies have shown that NK T cells are deficient in number and function in…”
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