Search Results - "CARMONA, F"

Approaches for enhanced phytoextraction of heavy metals by Bhargava, Atul, Carmona, Francisco F., Bhargava, Meenakshi, Srivastava, Shilpi

“…The contamination of the environment with toxic metals has become a worldwide problem. Metal toxicity affects crop yields, soil biomass and fertility. Soils…”
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PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition by Castel, Pau, Ellis, Haley, Bago, Ruzica, Toska, Eneda, Razavi, Pedram, Carmona, F. Javier, Kannan, Srinivasaraghavan, Verma, Chandra S., Dickler, Maura, Chandarlapaty, Sarat, Brogi, Edi, Alessi, Dario R., Baselga, José, Scaltriti, Maurizio

“…PIK3CA, which encodes the p110α subunit of PI3K, is frequently mutated and oncogenic in breast cancer. PI3Kα inhibitors are in clinical development and despite…”
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Distinct DNA methylomes of newborns and centenarians by Heyn, Holger, Li, Ning, Ferreira, Humberto J., Moran, Sebastian, Pisano, David G., Gomez, Antonio, Diez, Javier, Sanchez-Mut, Jose V., Setien, Fernando, Carmona, F. Javier, Puca, Annibale A., Sayols, Sergi, Pujana, Miguel A., Serra-Musach, Jordi, Iglesias-Platas, Isabel, Formiga, Francesc, Fernandez, Agustin F., Fraga, Mario F., Heath, Simon C., Valencia, Alfonso, Gut, Ivo G., Wang, Jun, Esteller, Manel

“…Human aging cannot be fully understood in terms of the constrained genetic setting. Epigenetic drift is an alternative means of explaining age-associated…”
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DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker by Heyn, Holger, Carmona, F Javier, Gomez, Antonio, Ferreira, Humberto J, Bell, Jordana T, Sayols, Sergi, Ward, Kirsten, Stefansson, Olafur A, Moran, Sebastian, Sandoval, Juan, Eyfjord, Jorunn E, Spector, Tim D, Esteller, Manel

“…Using whole blood from 15 twin pairs discordant for breast cancer and high-resolution (450K) DNA methylation analysis, we identified 403 differentially…”
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DNA Methylation Map of Human Atherosclerosis by Zaina, Silvio, Heyn, Holger, Carmona, F Javier, Varol, Nuray, Sayols, Sergi, Condom, Enric, Ramírez-Ruz, José, Gomez, Antonio, Gonçalves, Isabel, Moran, Sebastian, Esteller, Manel

“…BACKGROUND—Epigenetic alterations may contribute to the development of atherosclerosis. In particular, DNA methylation, a reversible and highly regulated DNA…”
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Genetic component of giant cell arteritis by Carmona, F David, González-Gay, Miguel A, Martín, Javier

“…Important steps forwards have been taken during recent years towards the understanding of the genetic basis of autoimmunity. The increasing number of study…”
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Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR by Vizoso, Miguel, Ferreira, Humberto J, Lopez-Serra, Paula, Carmona, F Javier, Martínez-Cardús, Anna, Girotti, Maria Romina, Villanueva, Alberto, Guil, Sonia, Moutinho, Catia, Liz, Julia, Portela, Anna, Heyn, Holger, Moran, Sebastian, Vidal, August, Martinez-Iniesta, Maria, Manzano, Jose L, Fernandez-Figueras, Maria Teresa, Elez, Elena, Muñoz-Couselo, Eva, Botella-Estrada, Rafael, Berrocal, Alfonso, Pontén, Fredrik, Oord, Joost van den, Gallagher, William M, Frederick, Dennie T, Flaherty, Keith T, McDermott, Ultan, Lorigan, Paul, Marais, Richard, Esteller, Manel

“…Epigenetic inactivation of a Rab GTPase activating protein confers metastatic properties in melanoma, and it correlates with poor prognosis but better…”
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Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review by López-Mejías, Raquel, Castañeda, Santos, Genre, Fernanda, Remuzgo-Martínez, Sara, Carmona, F. David, Llorca, Javier, Blanco, Ricardo, Martín, Javier, González-Gay, Miguel A.

“…Immunoglobulin-A vasculitis (IgAV) is classically a childhood small-sized blood vessel vasculitis with predominant involvement of the skin. Gastrointestinal…”
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Understanding of sliding and contact angle results in tilted plate experiments by Pierce, E., Carmona, F.J., Amirfazli, A.

“…Tilted plate experimental methodology is studied in order to address misinterpretations and omissions that exist in the literature. The effect of methodology…”
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Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2) by Cocco, Emiliano, Javier Carmona, F, Razavi, Pedram, Won, Helen H, Cai, Yanyan, Rossi, Valentina, Chan, Carmen, Cownie, James, Soong, Joanne, Toska, Eneda, Shifman, Sophie G, Sarotto, Ivana, Savas, Peter, Wick, Michael J, Papadopoulos, Kyriakos P, Moriarty, Alyssa, Cutler, Jr, Richard E, Avogadri-Connors, Francesca, Lalani, Alshad S, Bryce, Richard P, Chandarlapaty, Sarat, Hyman, David M, Solit, David B, Boni, Valentina, Loi, Sherene, Baselga, José, Berger, Michael F, Montemurro, Filippo, Scaltriti, Maurizio

“…Mutations in , the gene encoding epidermal growth factor receptor (EGFR) family member HER2, are common in and drive the growth of "HER2-negative" (not…”
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The potential of PTPN22 as a therapeutic target for rheumatoid arthritis by Carmona, F David, Martín, Javier

“…PTPN22 encodes a lymphoid-specific tyrosine phosphatase (LYP) that is a master regulator of the immune response. This gene is a major susceptibility factor for…”
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Genome-wide compound heterozygote analysis highlights DPY19L2 alleles in a non-consanguineous Spanish family with total globozoospermia by López-Rodrigo, Olga, Bossini-Castillo, Lara, Carmona, F. David, Bassas, Lluís, Larriba, Sara

“…Would the use of genome-wide genotyping be an advantageous strategy to identify the molecular aetiology of two brothers from a non-consanguineous family,…”
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DNA Methylation Biomarkers for Noninvasive Diagnosis of Colorectal Cancer by CARMONA, Javier F, AZUARA, Daniel, GUARDIOLA, Jordi, CAPELLA, Gabriel, ESTELLER, Manel, MORENO, Victor, BERENGUER-LLERGO, Antonio, FERNANDEZ, Agustin F, BIONDO, Sebastiano, DE OCA, Javier, RODRIGUEZ-MORANTA, Francisco, SALAZAR, Ramón, VILLANUEVA, Alberto, FRAGA, Mario F

“…DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer (CRC) and precursor lesions have been extensively studied. Different panels have been…”
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Evidence of high compliance and fatigue in mask adherence in two mandates in Barcelona, Spain: a naturalistic observational study by Gamez, J., Carmona, F., Gamez, A., Santos, M.

“…OBJECTIVEWe investigated a possible pandemic fatigue effect, comparing adherence to compulsory mask use outdoors in Barcelona during the fourth and sixth waves…”
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A Prognostic DNA Methylation Signature for Stage I Non–Small-Cell Lung Cancer by SANDOVAL, Juan, MENDEZ-GONZALEZ, Jesus, SANCHEZ-CESPEDES, Montse, ASSENOV, Yassen, MÜLLER, Fabian, BOCK, Christoph, TARON, Miquel, MORA, Josefina, MUSCARELLA, Lucia A, LILOGLOU, Triantafillos, DAVIES, Michael, POLLAN, Marina, NADAL, Ernest, PAJARES, Maria J, TORRE, Wenceslao, MONTUENGA, Luis M, BRAMBILLA, Elisabeth, FIELD, John K, ROZ, Luca, IACONO, Marco Lo, SCAGLIOTTI, Giorgio V, ROSELL, Rafael, BEER, David G, GUOAN CHEN, ESTELLER, Manel, CARMONA, F. Javier, SAYOLS, Sergi, MORAN, Sebastian, HEYN, Holger, VIZOSO, Miguel, GOMEZ, Antonio

“…Non-small-cell lung cancer (NSCLC) is a tumor in which only small improvements in clinical outcome have been achieved. The issue is critical for stage I…”
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AKT signaling in ERBB2-amplified breast cancer by Carmona, F Javier, Montemurro, Filippo, Kannan, Srinivasaraghavan, Rossi, Valentina, Verma, Chandra, Baselga, José, Scaltriti, Maurizio

“…The PI3K/AKT pathway is the focus of several targeted therapeutic agents for a variety of malignancies. In ERBB2-amplified breast cancer, the hyperactivation…”
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A GWAS in Idiopathic/Unexplained Infertile Men Detects a Genomic Region Determining Follicle-Stimulating Hormone Levels by Schubert, Maria, Pérez Lanuza, Lina, Wöste, Marius, Dugas, Martin, Carmona, F David, Palomino-Morales, Rogelio J, Rassam, Yousif, Heilmann-Heimbach, Stefanie, Tüttelmann, Frank, Kliesch, Sabine, Gromoll, Jörg

“…Approximately 70% of infertile men are diagnosed with idiopathic (abnormal semen parameters) or unexplained (normozoospermia) infertility, with the common…”
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Ovarian response is associated with anogenital distance in patients undergoing controlled ovarian stimulation for IVF by Fabregues, F, González-Foruria, I, Peñarrubia, J, Carmona, F

“…Abstract STUDY QUESTION Is the length of the anogenital distance (AGD) a biomarker of ovarian reserve and response to controlled ovarian stimulation (COS)?…”
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Genetic Landscape of Nonobstructive Azoospermia and New Perspectives for the Clinic by Cerván-Martín, Miriam, Castilla, José A, Palomino-Morales, Rogelio J, Carmona, F David

“…Nonobstructive azoospermia (NOA) represents the most severe expression of male infertility, involving around 1% of the male population and 10% of infertile…”
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Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer by MOUTINHO, Catia, MARTINEZ-CARDUS, Anna, ELEZ, Elena, TABERNERO, Josep, SALAZAR, Ramon, ABAD, Albert, ESTELLER, Manel, SANTOS, Cristina, NAVARRO-PEREZ, Valentin, MARTINEZ-BALIBREA, Eva, MUSULEN, Eva, CARMONA, F. Javier, SARTORE-BIANCHI, Andrea, CASSINGENA, Andrea, SIENA, Salvatore

“…A major problem in cancer chemotherapy is the existence of primary resistance and/or the acquisition of secondary resistance. Many cellular defects contribute…”
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