Search Results - "CARLETON GAJDUSEK, D"
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Neuronal cell death in transmissible spongiform encephalopathies (prion diseases) revisited: from apoptosis to autophagy
Published in International Journal of Biochemistry and Cell Biology (01-12-2004)“…Neuronal autophagy, like apoptosis, is one of the mechanisms of the programmed cell death (PCD). In this review, we summarize the presence of autophagic…”
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2
Infectivity Studies of Both Ash and Air Emissions from Simulated Incineration of Scrapie- Contaminated Tissues
Published in Environmental science & technology (15-11-2004)“…We investigated the effectiveness of 15 min exposures to 600 and 1000 °C in continuous flow normal and starved-air incineration-like conditions to inactivate…”
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Kuru and its contribution to medicine
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (27-11-2008)“…The solution of kuru led us to the solution of Creutzfeldt–Jakob disease and to the elucidation, in humans and other species, of previously unknown mechanisms…”
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4
Family clustering of Viliuisk encephalomyelitis in traditional and new geographic regions
Published in Emerging infectious diseases (01-09-2007)“…Viliuisk encephalomyelitis is an acute, often fatal, meningoencephalitis that tends to develop into a prolonged chronically progressive panencephalitis…”
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Review. Kuru and its contribution to medicine
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (27-11-2008)“…The solution of kuru led us to the solution of Creutzfeldt-Jakob disease and to the elucidation, in humans and other species, of previously unknown mechanisms…”
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6
Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease
Published in Science (American Association for the Advancement of Science) (20-02-1987)“…Four clones were isolated from an adult human brain complementary DNA library with an oligonucleotide probe corresponding to the first 20 amino acids of the…”
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A proposal for new criteria for the classification of hantaviruses, based on S and M segment protein sequences
Published in Infection, genetics and evolution (01-09-2009)“…Hantaviruses, members of the family Bunyaviridae, are the causative agents of hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome…”
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Early images of kuru and the people of Okapa
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (27-11-2008)Get full text
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The new biology of spongiform encephalopathy: infectious amyloidoses with a genetic twist
Published in The Lancet (British edition) (27-04-1991)Get more information
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Distinct Pathological Features of the Gallyas- and Tau-positive Glia in the Parkinsonism-Dementia Complex and Amyotrophic Lateral Sclerosis of Guam
Published in Journal of neuropathology and experimental neurology (01-03-1997)“…We examined 50 patients with parkinsonism-dementia complex of Guam (Guam PDC). 10 Guamanian patients with amyotrophic lateral sclerosis (ALS), 5 patients with…”
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HTLV-III Infection in Brains of Children and Adults with AIDS Encephalopathy
Published in Science (American Association for the Advancement of Science) (11-01-1985)“…Unexplained debilitating dementia or encephalopathy occurs frequently in adults and children with the acquired immune deficiency syndrome (AIDS). Brains from…”
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Highly Divergent Molecular Variants of Human T-Lymphotropic Virus Type I from Isolated Populations in Papua New Guinea and the Solomon Islands
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1991)“…To determine the molecular genetic relationship between Melanesian strains of human T-lymphotropic virus type I (HTLV-I) and cosmopolitan prototype HTLV-I, we…”
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13
Natural and Experimental Oral Infection of Nonhuman Primates by Bovine Spongiform Encephalopathy Agents
Published in Proceedings of the National Academy of Sciences - PNAS (30-03-1999)“…Experimental lemurs either were infected orally with the agent of bovine spongiform encephalopathy (BSE) or were maintained as unifected control animals…”
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14
New studies on the heat resistance of hamster-adapted scrapie agent: Threshold survival after ashing at 600°C suggests an inorganic template of replication
Published in Proceedings of the National Academy of Sciences - PNAS (28-03-2000)“…One-gram samples from a pool of crude brain tissue from hamsters infected with the 263K strain of hamster-adapted scrapie agent were placed in covered…”
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Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease
Published in Annals of neurology (01-05-1994)“…We present a synthesis of clinical, neuropathological, and biological details of the National Institutes of Health series of 300 experimentally transmitted…”
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Increased Susceptibility to Kuru of Carriers of the PRNP 129 Methionine/Methionine Genotype
Published in The Journal of infectious diseases (15-01-2001)“…Kuru reached epidemic proportions by the mid-twentieth century among the Fore people of New Guinea and disappeared after the abolition of cannibalistic…”
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Different Patterns of Truncated Prion Protein Fragments Correlate with Distinct Phenotypes in P102L Gerstmann--Straussler--Scheinker Disease
Published in Proceedings of the National Academy of Sciences - PNAS (07-07-1998)“…The clinicopathological phenotype of the Gerstmann--Straussler--Scheinker disease (GSS) variant linked to the codon 102 mutation in the prion protein (PrP)…”
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Belgrade Virus: A New Hantavirus Causing Severe Hemorrhagic Fever with Renal Syndrome in Yugoslavia
Published in The Journal of infectious diseases (01-07-1992)“…Two biologically and genetically distinct hantaviruses were isolated from blood and urine specimens collected from four Yugoslavian patients with clinically…”
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Phenotype-Genotype Studies in Kuru: Implications for New Variant Creutzfeldt-Jakob Disease
Published in Proceedings of the National Academy of Sciences - PNAS (27-10-1998)“…The PRNP polymorphic (methionine/valine) codon 129 genotype influences the phenotypic features of transmissible spongiform encephalopathy. All tested cases of…”
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Genetic Analysis of Creutzfeldt-Jakob Disease and Related Disorders
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29-03-1994)“…Genetic studies of over 200 cases of Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler-Scheinker syndrome (GSS), fatal familial insomnia (FFI) and kuru…”
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