Search Results - "CARIOU, BERTRAND"

The metabolic triad of non‐alcoholic fatty liver disease, visceral adiposity and type 2 diabetes: Implications for treatment by Cariou, Bertrand

“…Non‐alcoholic fatty liver disease (NAFLD) is associated with visceral obesity, insulin resistance, type 2 diabetes (T2D) and has been often considered as the…”
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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation by Lefebvre, Philippe, Cariou, Bertrand, Lien, Fleur, Kuipers, Folkert, Staels, Bart

“…Institut Pasteur de Lille, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 545, and Université de Lille 2, Faculté des Sciences…”
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Once-Daily Liraglutide Versus Lixisenatide as Add-on to Metformin in Type 2 Diabetes: A 26-Week Randomized Controlled Clinical Trial by Nauck, Michael, Rizzo, Manfredi, Johnson, Andrew, Bosch-Traberg, Heidrun, Madsen, Jesper, Cariou, Bertrand

“…To compare the efficacy and safety of liraglutide versus lixisenatide as add-on to metformin in patients with type 2 diabetes not achieving adequate glycemic…”
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Efficacy and safety of once-weekly semaglutide versus once-daily insulin glargine as add-on to metformin (with or without sulfonylureas) in insulin-naive patients with type 2 diabetes (SUSTAIN 4): a randomised, open-label, parallel-group, multicentre, multinational, phase 3a trial by Aroda, Vanita R, MD, Bain, Stephen C, Prof, Cariou, Bertrand, MD, Piletič, Milivoj, MD, Rose, Ludger, MD, Axelsen, Mads, MD, Rowe, Everton, PhD, DeVries, J Hans, Prof

“…Summary Background Several pharmacological treatment options are available for type 2 diabetes; however, many patients do not achieve optimum glycaemic control…”
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Hepatoprotective effects of the dual peroxisome proliferator‐activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis by Staels, Bart, Rubenstrunk, Anne, Noel, Benoit, Rigou, Géraldine, Delataille, Philippe, Millatt, Lesley J., Baron, Morgane, Lucas, Anthony, Tailleux, Anne, Hum, Dean W., Ratziu, Vlad, Cariou, Bertrand, Hanf, Rémy

“…Nonalcoholic fatty liver disease (NAFLD) covers a spectrum of liver damage ranging from simple steatosis to nonalcoholic steatohepatitis (NASH), fibrosis, and…”
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PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial by Raal, Frederick J, Prof, Stein, Evan A, Prof, Dufour, Robert, MD, Turner, Traci, MD, Civeira, Fernando, MD, Burgess, Lesley, Prof, Langslet, Gisle, MD, Scott, Russell, Prof, Olsson, Anders G, Prof, Sullivan, David, MD, Hovingh, G Kees, MD, Cariou, Bertrand, MD, Gouni-Berthold, Ioanna, MD, Somaratne, Ransi, MD, Bridges, Ian, MSc, Scott, Rob, MD, Wasserman, Scott M, MD, Gaudet, Daniel, Prof

“…Summary Background Heterozygous familial hypercholesterolaemia is characterised by low cellular uptake of LDL cholesterol, increased plasma LDL cholesterol…”
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Chronic O-GlcNAcylation and Diabetic Cardiomyopathy: The Bitterness of Glucose by Ducheix, Simon, Magré, Jocelyne, Cariou, Bertrand, Prieur, Xavier

“…Type 2 diabetes (T2D) is a major risk factor for heart failure. Diabetic cardiomyopathy (DC) is characterized by diastolic dysfunction and left ventricular…”
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Familial Hypercholesterolemia-Risk-Score: A New Score Predicting Cardiovascular Events and Cardiovascular Mortality in Familial Hypercholesterolemia by Paquette, Martine, Bernard, Sophie, Cariou, Bertrand, Hegele, Robert A., Genest, Jacques, Trinder, Mark, Brunham, Liam R., Béliard, Sophie, Baass, Alexis

“…Objective: Familial hypercholesterolemia (FH) is associated with a high risk of premature atherosclerotic cardiovascular disease (ASCVD). However, this risk is…”
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The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model by Joubert, Michael, Jagu, Benoît, Montaigne, David, Marechal, Xavier, Tesse, Angela, Ayer, Audrey, Dollet, Lucile, Le May, Cédric, Toumaniantz, Gilles, Manrique, Alain, Charpentier, Flavien, Staels, Bart, Magré, Jocelyne, Cariou, Bertrand, Prieur, Xavier

“…Type 2 diabetes mellitus (T2DM) is a well-recognized independent risk factor for heart failure. T2DM is associated with altered cardiac energy metabolism,…”
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COVID-19 and Diabetes Outcomes: Rationale for and Updates from the CORONADO Study by Smati, Sarra, Tramunt, Blandine, Wargny, Matthieu, Gourdy, Pierre, Hadjadj, Samy, Cariou, Bertrand

“…Purpose of Review In France, in order to describe the phenotypic characteristics of patients with diabetes hospitalized for coronavirus disease-2019 (COVID-19)…”
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Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1 by Le May, Cédric, Berger, Jean Mathieu, Lespine, Anne, Pillot, Bruno, Prieur, Xavier, Letessier, Eric, Hussain, M Mahmood, Collet, Xavier, Cariou, Bertrand, Costet, Philippe

“…OBJECTIVE—Transintestinal cholesterol excretion (TICE) is an alternate pathway to hepatobiliary secretion. Our study aimed at identifying molecular mechanisms…”
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Lipidomic analysis of adipose-derived extracellular vesicles reveals specific EV lipid sorting informative of the obesity metabolic state by Blandin, Alexia, Dugail, Isabelle, Hilairet, Grégory, Ponnaiah, Maharajah, Ghesquière, Valentine, Froger, Josy, Ducheix, Simon, Fizanne, Lionel, Boursier, Jérôme, Cariou, Bertrand, Lhomme, Marie, Le Lay, Soazig

“…Adipose extracellular vesicles (AdEVs) transport lipids that could participate in the development of obesity-related metabolic dysfunctions. This study aims to…”
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Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology by Tuñón, José, Badimón, Lina, Bochaton-Piallat, Marie-Luce, Cariou, Bertrand, Daemen, Mat J, Egido, Jesus, Evans, Paul C, Hoefer, Imo E, Ketelhuth, Daniel F J, Lutgens, Esther, Matter, Christian M, Monaco, Claudia, Steffens, Sabine, Stroes, Erik, Vindis, Cécile, Weber, Christian, Bäck, Magnus

“…Abstract Dysregulated lipid metabolism induces an inflammatory and immune response leading to atherosclerosis. Conversely, inflammation may alter lipid…”
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Protection against stroke with glucagon-like peptide-1 receptor agonists: a comprehensive review of potential mechanisms by Vergès, Bruno, Aboyans, Victor, Angoulvant, Denis, Boutouyrie, Pierre, Cariou, Bertrand, Hyafil, Fabien, Mohammedi, Kamel, Amarenco, Pierre

“…Several randomized controlled trials have demonstrated the benefits of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on ischemic stroke in patients with…”
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Early humoral response to COVID-19 vaccination in patients living with obesity and diabetes in France. The COVPOP OBEDIAB study with results from the ANRS0001S COV-POPART cohort by Gaborit, Bénédicte, Fernandes, Sara, Loubet, Paul, Ninove, Laetitia, Dutour, Anne, Cariou, Bertrand, Coupaye, Muriel, Clement, Karine, Czernichow, Sébastien, Carette, Claire, Resseguier, Noémie, Esterle, Laure, Kali, Sabrina, Houssays, Marie, de Lamballerie, Xavier, Wittkop, Linda, Launay, Odile, Laville, Martine

“…Patients with diabetes and obesity are populations at high-risk for severe COVID-19 outcomes and have shown blunted immune responses when administered…”
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Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity by PRAWITT, Janne, ABDELKARIM, Mouaadh, DORCHIES, Emilie, DAOUDI, Mehdi, LESTAVEL, Sophie, GONZALEZ, Frank J, ORESIC, Matej, CARIOU, Bertrand, KUIPERS, Folkert, CARON, Sandrine, STAELS, Bart, STROEVE, Johanna H. M, POPESCU, Iuliana, DUEZ, Helene, VELAGAPUDI, Vidya R, DUMONT, Julie, BOUCHAERT, Emmanuel, VAN DIJK, Theo H, LUCAS, Anthony

“…Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through different signaling pathways. The nuclear BA receptor farnesoid X…”
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Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes by Caron, Sandrine, Huaman Samanez, Carolina, Dehondt, Hélène, Ploton, Maheul, Briand, Olivier, Lien, Fleur, Dorchies, Emilie, Dumont, Julie, Postic, Catherine, Cariou, Bertrand, Lefebvre, Philippe, Staels, Bart

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Fatty liver index is a strong predictor of changes in glycemic status in people with prediabetes: The IT-DIAB study by Wargny, Matthieu, Smati, Sarra, Pichelin, Matthieu, Bigot-Corbel, Edith, Authier, Charlotte, Dierry, Violette, Zaïr, Yassine, Jacquin, Vincent, Hadjadj, Samy, Boursier, Jérôme, Cariou, Bertrand

“…In patients at metabolic risk, nonalcoholic fatty liver disease is a strong and highly prevalent predictor for type 2 diabetes. Its assessment in clinical…”
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Circulating Rather Than Intestinal PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Regulates Postprandial Lipemia in Mice by Garçon, Damien, Moreau, François, Ayer, Audrey, Dijk, Wieneke, Prieur, Xavier, Arnaud, Lucie, Roubtsova, Anna, Seidah, Nabil, Prat, Annik, Cariou, Bertrand, Le May, Cédric

“…Objective: Increased postprandial lipemia (PPL) is an independent risk factor for atherosclerotic cardiovascular diseases. PCSK9 (Proprotein convertase…”
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VLDL (Very-Low-Density Lipoprotein)-Apo E (Apolipoprotein E) May Influence Lp(a) (Lipoprotein [a]) Synthesis or Assembly by Croyal, Mikaël, Blanchard, Valentin, Ouguerram, Khadija, Chétiveaux, Maud, Cabioch, Léa, Moyon, Thomas, Billon-Crossouard, Stéphanie, Aguesse, Audrey, Bernardeau, Karine, Le May, Cédric, Flet, Laurent, Lambert, Gilles, Hadjadj, Samy, Cariou, Bertrand, Krempf, Michel, Nobécourt-Dupuy, Estelle

“…To clarify the association between PCSK9 (proprotein convertase subtilisin/kexin type 9) and Lp(a) (lipoprotein [a]), we studied Lp(a) kinetics in patients…”
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