Search Results - "CARACCIOLO, G"

An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles by Digiacomo, L, Cardarelli, F, Pozzi, D, Palchetti, S, Digman, M A, Gratton, E, Capriotti, A L, Mahmoudi, M, Caracciolo, G

“…Following exposure to biological milieus (e.g. after systemic administration), nanoparticles (NPs) get covered by an outer biomolecular corona (BC) that…”
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The biomolecular corona of nanoparticles in circulating biological media by Pozzi, D, Caracciolo, G, Digiacomo, L, Colapicchioni, V, Palchetti, S, Capriotti, A L, Cavaliere, C, Zenezini Chiozzi, R, Puglisi, A, Laganà, A

“…When nanoparticles come into contact with biological media, they are covered by a biomolecular 'corona', which confers a new identity to the particles. In all…”
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Nanoparticles-cell association predicted by protein corona fingerprints by Palchetti, S, Digiacomo, L, Pozzi, D, Peruzzi, G, Micarelli, E, Mahmoudi, M, Caracciolo, G

“…In a physiological environment (e.g., blood and interstitial fluids) nanoparticles (NPs) will bind proteins shaping a "protein corona" layer. The long-lived…”
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Clinically approved PEGylated nanoparticles are covered by a protein corona that boosts the uptake by cancer cells by Papi, M, Caputo, D, Palmieri, V, Coppola, R, Palchetti, S, Bugli, F, Martini, C, Digiacomo, L, Pozzi, D, Caracciolo, G

“…Today, liposomes are an advanced technology of drug carriers with a dozen drugs in clinical practice and many more in clinical trials. A bottleneck associated…”
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Mechanistic evaluation of the transfection barriers involved in lipid-mediated gene delivery: Interplay between nanostructure and composition by Pozzi, D., Marchini, C., Cardarelli, F., Salomone, F., Coppola, S., Montani, M., Zabaleta, M. Elexpuru, Digman, M.A., Gratton, E., Colapicchioni, V., Caracciolo, G.

“…Here we present a quantitative mechanism-based investigation aimed at comparing the cell uptake, intracellular trafficking, endosomal escape and final fate of…”
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In vivo protein corona patterns of lipid nanoparticles by Amici, A., Caracciolo, G., Digiacomo, L., Gambini, V., Marchini, C., Tilio, M., Capriotti, A. L., Colapicchioni, V., Matassa, R., Familiari, G., Palchetti, S., Pozzi, D., Mahmoudi, M., Laganà, A.

“…In physiological environments ( e.g. the blood), nanoparticles (NPs) are surrounded by a layer of biomolecules referred to as a ‘protein corona’ (PC). The most…”
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Exact occupation probabilities for intermittent transport and application to image correlation spectroscopy by Coppola, S, Caracciolo, G, Schmidt, T

“…Intermittent transport is frequently observed in nature and has been proven to accelerate search processes at both the macroscopic (e.g., animals looking for…”
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Improving the accuracy of pancreatic cancer clinical staging by exploitation of nanoparticle-blood interactions: A pilot study by Caputo, D., Cartillone, M., Cascone, C., Pozzi, D., Digiacomo, L., Palchetti, S., Caracciolo, G., Coppola, R.

“…Pancreatic ductal adenocarcinoma (PDAC) early diagnosis is  crucial  and new, cheap and user-friendly techniques for biomarker identification  are  needed…”
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Biophysics and protein corona analysis of Janus cyclodextrin-DNA nanocomplexes. Efficient cellular transfection on cancer cells by Martínez-Negro, M., Caracciolo, G., Palchetti, S., Pozzi, D., Capriotti, A.L., Cavaliere, C., Laganà, A., Ortiz Mellet, C., Benito, J.M., García Fernández, J.M., Aicart, E., Junquera, E.

“…The self-assembling processes underlining the capabilities of facially differentiated (“Janus”) polycationic amphiphilic cyclodextrins (paCDs) as non-viral…”
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Mechanistic Understanding of Gene Delivery Mediated by Highly Efficient Multicomponent Envelope-Type Nanoparticle Systems by Pozzi, D, Marchini, C, Cardarelli, F, Rossetta, A, Colapicchioni, V, Amici, A, Montani, M, Motta, S, Brocca, P, Cantù, L, Caracciolo, G

“…We packaged condensed DNA/protamine particles in multicomponent envelope-type nanoparticle systems (MENS) combining different molar fractions of the cationic…”
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A proteomics-based methodology to investigate the protein corona effect for targeted drug delivery by Pozzi, D, Caracciolo, G, Capriotti, A L, Cavaliere, C, Piovesana, S, Colapicchioni, V, Palchetti, S, Riccioli, A, Laganà, A

“…Here we introduce a proteomics methodology based on nanoliquid-chromatography tandem mass spectrometry (nanoLC/MS-MS) to investigate the "protein corona effect…”
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EFFECTS OF PRE-PLANT SOIL TREATMENTS ON STRAWBERRY IN SICILY by F. D¿Anna, G. Caracciolo, A. Parrinello, G. Baruzzi

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Model for End-stage Liver Disease Dynamic Stratification of Survival Benefit by Avolio, A.W, Siciliano, M, Barone, M, Lai, Q, Caracciolo, G.L, Barbarino, R, Nicolotti, N, Lirosi, M.C, Gasbarrini, A, Agnes, S

“…Abstract Only patients with Model for End-stage Liver Disease (MELD) scores ≥18 or ≥17 experience a survival benefit (SB) at 12 and 36 months after liver…”
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579 ENDOTHELIAL DYSFUNCTION IN CIRRHOSIS AND ITS RELATIONSHIP WITH PORTAL HYPERTENSION AND LIVER FAILURE by Garcovich, M, Lupascu, A, Roccarina, D, Annicchiarico, E.B, Ainora, M.E, Caracciolo, G, Ponziani, F.R, Siciliano, M, Gasbarrini, A, Zocco, M.A

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P1023 OUR PRELIMINARY EXPERIENCE WITH ElastPQ SHEAR WAVE ELASTOGRAPHY TECHNIQUE AND DOPPLER INDICES IN THE NON-INVASIVE ASSESSMENT OF LIVER FIBROSIS by Garcovich, M, Zocco, M.A, Riccardi, L, Annicchiarico, E.B, Ainora, M.E, Roccarina, D, Caracciolo, G, Grieco, A, Rapaccini, G.L, Siciliano, M, Pompili, M, Gasbarrini, A

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UPDATE ON THE SICILIAN STRAWBERRY BREEDING PROJECT by F. D¿Anna, G. Caracciolo, C. Prinzivalli, W. Faedi, G. Baruzzi, P. Sbrighi

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P.09.7 GELATINE TANNATE REDUCES ANTIBIOTICS ASSOCIATED SIDE-EFFECTS OF ANTI-HELICOBACTER PYLORI FIRST-LINE THERAPY by Gigante, G, Caracciolo, G, Campanale, M, Cesario, V, Gasbarrini, G, Cammarota, G, Gasbarrini, A

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Role of temperature-independent lipoplex-cell membrane interactions in the efficiency boost of multicomponent lipoplexes by Marchini, C, Pozzi, D, Montani, M, Alfonsi, C, Amici, A, Candeloro De Sanctis, S, Digman, M A, Sanchez, S, Gratton, E, Amenitsch, H, Fabbretti, A, Gualerzi, C O, Caracciolo, G

“…Multicomponent lipoplexes have recently emerged as especially promising transfection candidates, as they are from 10 to 100 times more efficient than binary…”
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P.11.20 CLINICAL OUTCOME OF PARTIAL PORTAL VEIN THROMBOSIS IN CIRRHOTIC PATIENTS: TO OBSERVE OR TO TREAT? by Caracciolo, G, Garcovich, M, Zocco, M.A, Ainora, M.E, Roccarina, D, Annicchiarico, B.E, Ponziani, F.R, Siciliano, M, Gasbarrini, A

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P.16.15 FEASIBILITY AND ACCURACY OF ELASTPQ® SHEAR WAVE ELASTOGRAPHY TECHNIQUE AND DOPPLER INDICES IN THE NON-INVASIVE ASSESSEMENT OF LIVER FIBROSIS: A PRELIMINARY EXPERIENCE by Garcovich, M, Zocco, M.A, Riccardi, L, Roccarina, D, Annicchiarico, B.E, Ainora, M.E, Caracciolo, G, Ponziani, F.R, Grieco, A, Siciliano, M, Pompili, M, Gasbarrini, A

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