Search Results - "CAPUTO, Antonella"
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Novel Chitosan-Based Schiff Base Compounds: Chemical Characterization and Antimicrobial Activity
Published in Molecules (Basel, Switzerland) (24-04-2022)“…Chitosan (CS) and its derivatives are receiving considerable attention for their great biocompatibility and broad-spectrum activities in many fields. In this…”
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Kaposi's Sarcoma Lesion Progression in BKV-Tat Transgenic Mice Is Increased by Inflammatory Cytokines and Blocked by Treatment with Anti-Tat Antibodies
Published in International journal of molecular sciences (14-02-2022)“…Kaposi's sarcoma (KS) is an angioproliferative tumor showing an increased frequency and aggressiveness in HIV-infected subjects (AIDS-KS), due to the combined…”
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Vaccine Development for Herpes Simplex Viruses: A Commentary of Special Issue Editors
Published in Vaccines (Basel) (16-02-2021)“…Herpes simplex virus type 1 and 2 (HSV1 and HSV2) are global, widespread human pathogens transmitted by direct contact that cause lifelong, recurrent…”
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Regulation of TMEM16A Chloride Channel Properties by Alternative Splicing
Published in The Journal of biological chemistry (27-11-2009)“…Expression of TMEM16A protein is associated with the activity of Ca2+-activated Cl− channels. TMEM16A primary transcript undergoes alternative splicing. thus…”
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TMEM16A Protein: A New Identity for Ca2+-Dependent Cl- Channels
Published in Physiology (Bethesda, Md.) (01-12-2010)“…Ca+-dependent Cl- channels (CaCCs) play a variety of physiological roles in different organs and tissues, including transepithelial Cl- secretion, smooth…”
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Naïve CD8 + T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8 + T-Cells
Published in Frontiers in immunology (21-12-2018)“…Characterization of the intracellular biochemical processes that regulate the generation and maintenance of effector and memory CD8 T-cells from naïve…”
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Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects
Published in Frontiers in immunology (13-07-2021)“…Advanced age is associated with severe symptoms and death upon SARS-CoV-2 infection. Virus-specific CD8 + T-cell responses have shown to be protective toward…”
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Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity
Published in GeroScience (01-08-2020)Get full text
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In Chronic Hepatitis C Infection, Myeloid-Derived Suppressor Cell Accumulation and T Cell Dysfunctions Revert Partially and Late After Successful Direct-Acting Antiviral Treatment
Published in Frontiers in cellular and infection microbiology (14-06-2019)“…Chronic HCV infection is characterized by several immunological alterations, such as the accumulation of suppressor cells and of hyperactivated T lymphocytes…”
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Effects of the age of vaccination on the humoral responses to a human papillomavirus vaccine
Published in npj vaccines (15-03-2022)“…Adult vaccination programs are receiving increasing attention however, little is known regarding the impact of age on the maintenance of the immune response…”
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Processing of retinal signals in normal and HCN deficient mice
Published in PloS one (18-01-2012)“…This study investigates the role of two different HCN channel isoforms in the light response of the outer retina. Taking advantage of HCN-deficient mice models…”
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HPV-Specific Systemic Antibody Responses and Memory B Cells are Independently Maintained up to 6 Years and in a Vaccine-Specific Manner Following Immunization with Cervarix and Gardasil in Adolescent and Young Adult Women in Vaccination Programs in Italy
Published in Vaccines (Basel) (14-01-2020)“…Human papillomavirus (HPV) persistent infections are associated with cervical cancer and other HPV-related diseases and tumors. Thus, the characterization of…”
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The HIV-1 Tat protein induces the activation of CD8+ T cells and affects in vivo the magnitude and kinetics of antiviral responses
Published in PloS one (04-11-2013)“…T cells are functionally compromised during HIV infection despite their increased activation and proliferation. Although T cell hyperactivation is one of the…”
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Thiocyanate Transport in Resting and IL-4-Stimulated Human Bronchial Epithelial Cells: Role of Pendrin and Anion Channels
Published in Journal of Immunology (15-04-2007)“…SCN(-) (thiocyanate) is an important physiological anion involved in innate defense of mucosal surfaces. SCN(-) is oxidized by H(2)O(2), a reaction catalyzed…”
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Increased excitability in tat -transgenic mice: Role of tat in HIV-related neurological disorders
Published in Neurobiology of disease (01-07-2013)“…Abstract HIV-1 associated neurocognitive disorders (HAND) are a major complication of HIV-1 infection. The mechanism(s) underlying HAND are not completely…”
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Ageing Curtails the Diversity and Functionality of Nascent CD8 + T Cell Responses against SARS-CoV-2
Published in Vaccines (Basel) (01-01-2023)“…Age-related changes in the immune system are thought to underlie the vulnerability of elderly individuals to emerging viral diseases, such as coronavirus…”
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Focus group study on perceptions and information needs regarding vaccines targeting the older population: a cross-country comparison in four European countries
Published in GeroScience (01-04-2023)“…The increasing life expectancy leads to more older adults suffering from infectious diseases. Vaccines are available against diverse infections such as…”
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An attenuated herpes simplex virus type 1 (HSV1) encoding the HIV-1 Tat protein protects mice from a deadly mucosal HSV1 challenge
Published in PloS one (17-07-2014)“…Herpes simplex virus types 1 and 2 (HSV1 and HSV2) are common infectious agents in both industrialized and developing countries. They cause recurrent…”
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Altered protease-activated receptor-1 expression and signaling in a malignant pleural mesothelioma cell line, NCI-H28, with homozygous deletion of the β-catenin gene
Published in PloS one (03-11-2014)“…Protease activated receptors (PARs) are G-protein coupled receptors that are activated by an unique proteolytic mechanism. These receptors play crucial roles…”
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