Search Results - "CAPO, Christian"
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The two faces of interleukin 10 in human infectious diseases
Published in The Lancet infectious diseases (01-09-2006)“…Resolution of infections depends on the host's ability to mount a protective immune response. However, an exacerbated response to infections may result in…”
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2
Epidemic typhus
Published in The Lancet infectious diseases (01-07-2008)“…Summary Epidemic typhus is transmitted to human beings by the body louse Pediculus humanus corporis . The disease is still considered a major threat by…”
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3
Ameobal pathogen mimivirus infects macrophages through phagocytosis
Published in PLoS pathogens (01-06-2008)“…Mimivirus, or Acanthamoeba polyphaga mimivirus (APMV), a giant double-stranded DNA virus that grows in amoeba, was identified for the first time in 2003. Entry…”
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4
Persistence of Coxiella burnetii, the agent of Q fever, in murine adipose tissue
Published in PloS one (16-05-2014)“…Coxiella burnetii, the agent of Q fever, is known to persist in humans and rodents but its cellular reservoir in hosts remains undetermined. We hypothesized…”
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Intracellular bacteria interfere with dendritic cell functions: role of the type I interferon pathway
Published in PloS one (10-06-2014)“…Dendritic cells (DCs) orchestrate host defenses against microorganisms. In infectious diseases due to intracellular bacteria, the inefficiency of the immune…”
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Monocyte Responses in the Context of Q Fever: From a Static Polarized Model to a Kinetic Model of Activation
Published in The Journal of infectious diseases (15-09-2013)“…Background. Q fever is caused by Coxiella burnetii, a bacterium that persists in M2-polarized macrophages. We wondered whether the concept of M1/M2…”
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Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response
Published in PloS one (14-12-2010)“…Q fever is a zoonosis caused by Coxiella burnetii, an obligate intracellular bacterium typically found in myeloid cells. The infection is a source of severe…”
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The gene expression analysis of blood reveals S100A11 and AQP9 as potential biomarkers of infective endocarditis
Published in PloS one (03-02-2012)“…The diagnostic and prognostic assessments of infective endocarditis (IE) are challenging. To investigate the host response during IE and to identify potential…”
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Imbalance of circulating monocyte subsets and PD-1 dysregulation in Q fever endocarditis: the role of IL-10 in PD-1 modulation
Published in PloS one (11-09-2014)“…Q fever endocarditis, a severe complication of Q fever, is associated with a defective immune response, the mechanisms of which are poorly understood. We…”
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Orientia tsutsugamushi stimulates an original gene expression program in monocytes: relationship with gene expression in patients with scrub typhus
Published in PLoS neglected tropical diseases (01-05-2011)“…Orientia tsutsugamushi is the causal agent of scrub typhus, a public health problem in the Asia-Pacific region and a life-threatening disease. O. tsutsugamushi…”
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Persistent Coxiella burnetii infection in mice overexpressing IL-10: an efficient model for chronic Q fever pathogenesis
Published in PLoS pathogens (01-02-2008)“…Interleukin (IL)-10 increases host susceptibility to microorganisms and is involved in intracellular persistence of bacterial pathogens. IL-10 is associated…”
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Sex-related differences in gene expression following Coxiella burnetii infection in mice: potential role of circadian rhythm
Published in PloS one (13-08-2010)“…Q fever, a zoonosis due to Coxiella burnetii infection, exhibits sexual dimorphism; men are affected more frequently and severely than women for a given…”
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Adipose tissue serves as a reservoir for recrudescent Rickettsia prowazekii infection in a mouse model
Published in PloS one (01-01-2010)“…Brill-Zinsser disease, the relapsing form of epidemic typhus, typically occurs in a susceptible host years or decades after the primary infection; however, the…”
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Global analysis of circulating immune cells by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
Published in PloS one (27-10-2010)“…MALDI-TOF mass spectrometry is currently used in microbiological diagnosis to characterize bacterial populations. Our aim was to determine whether this…”
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IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation
Published in PloS one (21-10-2010)“…The replication of Tropheryma whipplei (the agent of Whipple's disease) within human macrophages is associated with the expression of IL-16, a cytokine known…”
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The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis
Published in PLoS pathogens (16-05-2008)“…Patients with valvulopathy have the highest risk to develop infective endocarditis (IE), although the relationship between valvulopathy and IE is not clearly…”
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The transcriptional programme of human heart valves reveals the natural history of infective endocarditis
Published in PloS one (28-01-2010)“…Infective endocarditis (IE) is an infectious disease that is mainly caused by Staphylococcus aureus and Streptococcus sp. It usually leads to valvular…”
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New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis
Published in PloS one (28-04-2009)“…Tracheal glands (TG) may play a specific role in the pathogenesis of cystic fibrosis (CF), a disease due to mutations in the cftr gene and characterized by…”
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Survival of Tropheryma whipplei, the Agent of Whipple's Disease, Requires Phagosome Acidification
Published in Infection and Immunity (01-03-2002)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Coxiella burnetii Survives in Monocytes from Patients with Q Fever Endocarditis: Involvement of Tumor Necrosis Factor
Published in Infection and Immunity (01-01-2000)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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