Search Results - "CAPLICE, Noel M"

Is Adipose Tissue a Reservoir for Viral Spread, Immune Activation, and Cytokine Amplification in Coronavirus Disease 2019? by Ryan, Paul MacDaragh, Caplice, Noel M.

“…Coronavirus disease 2019 (COVID‐19), the worst pandemic in more than a century, has claimed >125,000 lives worldwide to date. Emerging predictors for poor…”
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Systemic and Cardiac Depletion of M2 Macrophage through CSF-1R Signaling Inhibition Alters Cardiac Function Post Myocardial Infarction by Leblond, Anne-Laure, Klinkert, Kerstin, Martin, Kenneth, Turner, Elizebeth C, Kumar, Arun H, Browne, Tara, Caplice, Noel M

“…The heart hosts tissue resident macrophages which are capable of modulating cardiac inflammation and function by multiple mechanisms. At present, the…”
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Mesenchymal stromal cell derived CCL2 is required for accelerated wound healing by Whelan, Derek S., Caplice, Noel M., Clover, Anthony J. P.

“…Mesenchymal stromal cells (MSC) have immunomodulatory effects impacting macrophages, promoting polarisation towards a reparative phenotype. CCL2 is a potent…”
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Bile acids at the cross-roads of gut microbiome-host cardiometabolic interactions by Ryan, Paul M, Stanton, Catherine, Caplice, Noel M

“…While basic and clinical research over the last several decades has recognized a number of modifiable risk factors associated with cardiometabolic disease…”
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Clinical Potential of Adult Vascular Progenitor Cells by Kumar, Arun H.S, Caplice, Noel M

“…Cell therapy to treat vascular and cardiovascular diseases has evolved over the past decade with improved understanding of progenitor cell mobilization,…”
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Bone Marrow‐Derived Mesenchymal Stem Cells Have Innate Procoagulant Activity and Cause Microvascular Obstruction Following Intracoronary Delivery: Amelioration by Antithrombin Therapy by Gleeson, Birgitta M., Martin, Kenneth, Ali, Mohammed T., Kumar, Arun H. S., Pillai, M. Gopala‐Krishnan, Kumar, Sujith P. G., O'Sullivan, John F., Whelan, Derek, Stocca, Alessia, Khider, Wisam, Barry, Frank P., O'Brien, Timothy, Caplice, Noel M.

“…Mesenchymal stem cells (MSCs) are currently under investigation as tools to preserve cardiac structure and function following acute myocardial infarction…”
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Exploring the Gut Microbiota and Cardiovascular Disease by Murphy, Kiera, O’Donovan, Aoife N., Caplice, Noel M., Ross, R. Paul, Stanton, Catherine

“…Cardiovascular disease (CVD) has been classified as one of the leading causes of morbidity and mortality worldwide. CVD risk factors include smoking,…”
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Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells by Ingram, David A., Caplice, Noel M., Yoder, Mervin C.

“…The field of vascular biology has been stimulated by the concept that circulating endothelial progenitor cells (EPCs) may play a role in neoangiogenesis…”
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Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1 by Hynes, Brian, Kumar, Arun H S, O'Sullivan, John, Klein Buneker, Chirlei, Leblond, Anne-Laure, Weiss, Sharon, Schmeckpeper, Jeffrey, Martin, Kenneth, Caplice, Noel M

“…We have previously reported the cardioprotective effects of endothelial progenitor cell (EPC)-conditioned media (CM) therapy post-myocardial infarction (MI)…”
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Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E -/- mice by Ryan, Paul M, London, Lis E E, Bjorndahl, Trent C, Mandal, Rupasri, Murphy, Kiera, Fitzgerald, Gerald F, Shanahan, Fergus, Ross, R Paul, Wishart, David S, Caplice, Noel M, Stanton, Catherine

“…There is strong evidence indicating that gut microbiota have the potential to modify, or be modified by the drugs and nutritional interventions that we rely…”
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Synthetic Chemically Modified mRNA-Based Delivery of Cytoprotective Factor Promotes Early Cardiomyocyte Survival Post-Acute Myocardial Infarction by Huang, Chien-Ling, Leblond, Anne-Laure, Turner, Elizebeth C, Kumar, Arun Hs, Martin, Kenneth, Whelan, Derek, O’Sullivan, Donnchadh M, Caplice, Noel M

“…To extend the temporal window for cytoprotection in cardiomyocytes undergoing apoptosis after hypoxia and myocardial infarction (MI), a synthetic chemically…”
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Selective M2 Macrophage Depletion Leads to Prolonged Inflammation in Surgical Wounds by Klinkert, Kerstin, Whelan, Derek, Clover, Anthony J P, Leblond, Anne-Laure, Kumar, Arun H S, Caplice, Noel M

“…A prolonged inflammatory phase is seen in aberrant wound healing and in chronic wounds. Macrophages are central to wound healing. Distinct macrophage subtypes…”
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Smooth muscle progenitor cells in human blood by SIMPER, David, STALBOERGER, Paul G, PANETTA, Carmelo J, SHAOHUA WANG, CAPLICE, Noel M

“…Recent animal data suggest that vascular smooth muscle cells within the neointima of the vessel wall may originate from bone marrow, providing indirect…”
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Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe by Ryan, Paul M, Stolte, Ellen H, London, Lis E E, Wells, Jerry M, Long, Sarah L, Joyce, Susan A, Gahan, Cormac G M, Fitzgerald, Gerald F, Ross, R Paul, Caplice, Noel M, Stanton, Catherine

“…Lactobacillus mucosae DPC 6426 has previously demonstrated potentially cardio-protective properties, in the form of dyslipidaemia and hypercholesterolemia…”
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Transplantation of circulating endothelial progenitor cells restores endothelial function of denuded rabbit carotid arteries by TONGRONG HE, SMITH, Leslie A, HARRINGTON, Sean, NATH, Karl A, CAPLICE, Noel M, KATUSIC, Zvonimir S

“…Circulating endothelial progenitor cells (EPCs) play an important role in repair of injured vascular endothelium and neovascularization. The present study was…”
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Role of CX3CR1 receptor in monocyte/macrophage driven neovascularization by Kumar, Arun H S, Martin, Kenneth, Turner, Elizebeth C, Buneker, Chirlei K, Dorgham, Karim, Deterre, Philippe, Caplice, Noel M

“…Monocyte/macrophages are implicated in initiation of angiogenesis, tissue/organ perfusion and atherosclerosis biology. We recently showed that chemokine…”
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Regenerative approaches to post-myocardial infarction heart failure by Martin, Kenneth, Huang, Chien-Ling, Caplice, Noel M

“…Loss of cardiac function following myocardial infarction (MI) remains a leading cause of morbidity in the developed world. Current percutaneous coronary…”
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Microbial bile salt hydrolase activity influences gene expression profiles and gastrointestinal maturation in infant mice by Núñez-Sánchez, María A, Herisson, Florence M, Keane, Jonathan M, García-González, Natalia, Rossini, Valerio, Pinhiero, Jorge, Daly, Jack, Bustamante-Garrido, Milán, Hueston, Cara M, Patel, Shriram, Canela, Nuria, Herrero, Pol, Claesson, Marcus J, Melgar, Silvia, Nally, Ken, Caplice, Noel M, Gahan, Cormac G M

“…The mechanisms by which early microbial colonizers of the neonate influence gut development are poorly understood. Bacterial bile salt hydrolase (BSH) acts as…”
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Smooth Muscle Cells in Human Coronary Atherosclerosis Can Originate from Cells Administered at Marrow Transplantation by Caplice, Noel M., Bunch, T. Jared, Stalboerger, Paul G., Wang, Shaohua, Simper, David, Miller, Dylan V., Russell, Stephen J., Litzow, Mark R., Edwards, William D.

“…Atherosclerosis is the major cause of adult mortality in the developed world, and a significant contributor to atherosclerotic plaque progression involves…”
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Human Endothelial Progenitor Cells Tolerate Oxidative Stress Due to Intrinsically High Expression of Manganese Superoxide Dismutase by He, Tongrong, Peterson, Timothy E, Holmuhamedov, Ekhson L, Terzic, Andre, Caplice, Noel M, Oberley, Larry W, Katusic, Zvonimir S

“…OBJECTIVE—Endothelial progenitor cells (EPCs) display a unique aptitude to promote angiogenesis and restore endothelial function of injured vessels. How…”
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