Search Results - "CAPECCHI, Barbara"
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A Universal Vaccine for Serogroup B Meningococcus
Published in Proceedings of the National Academy of Sciences - PNAS (18-07-2006)“…Meningitis and sepsis caused by serogroup B meningococcus are two severe diseases that still cause significant mortality. To date there is no universal vaccine…”
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NadA, a novel vaccine candidate of Neisseria meningitidis
Published in The Journal of experimental medicine (03-06-2002)“…Neisseria meningitidis is a human pathogen, which, in spite of antibiotic therapy, is still a major cause of mortality due to sepsis and meningitis. Here we…”
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NadA Diversity and Carriage in Neisseria meningitidis
Published in Infection and Immunity (01-07-2004)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Neisseria meningitidis NhhA is a multifunctional trimeric autotransporter adhesin
Published in Molecular microbiology (01-08-2006)“…Summary NhhA, Neisseriahia/hsf homologue, or GNA0992, is an oligomeric outer membrane protein of Neisseria meningitidis, recently included in the family of…”
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Mapping of the Neisseria meningitidis NadA Cell-Binding Site: Relevance of Predicted α-Helices in the NH2-Terminal and Dimeric Coiled-Coil Regions
Published in Journal of Bacteriology (01-01-2011)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human monocytes/macrophages are a target of Neisseria meningitidis Adhesin A (NadA)
Published in Journal of leukocyte biology (01-05-2008)“…Specific surface proteins of Neisseria meningitidis have been proposed to stimulate leukocytes during tissue invasion and septic shock. In this study, we…”
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Monocyte-activation test to reliably measure the pyrogenic content of a vaccine: An in vitro pyrogen test to overcome in vivo limitations
Published in Vaccine (27-06-2019)“…Pyrogen content is one of the critical quality attributes impacting the safety of a product, and there is an increasing need for assays that can reliably…”
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Approaches to Target Conserved Conformational Epitopes in HIV Envelope
Published in Retrovirology (08-12-2005)Get full text
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Neisseria meningitidis NadA is a new invasin which promotes bacterial adhesion to and penetration into human epithelial cells
Published in Molecular microbiology (01-02-2005)“…Summary Neisseria meningitidis is a human pathogen, which is a major cause of sepsis and meningitis. The bacterium colonizes the upper respiratory tract…”
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Impact of preexisting memory to seasonal A/H1N1 influenza virus on the immune response following vaccination against avian A/H5N1 virus
Published in European journal of immunology (01-03-2013)“…Cross‐protection against divergent strains of influenza virus is an objective of various vaccination approaches. B cells cross‐neutralizing several influenza A…”
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Pseudoparticle neutralization is a reliable assay to measure immunity and cross-reactivity to H5N1 influenza viruses
Published in Vaccine (09-10-2009)“…Abstract The standard serological methods present limitations for the measurement of immunity against H5N1 influenza strains. The hemagglutination inhibition…”
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Identification of Vaccine Candidates against Serogroup B Meningococcus by Whole-Genome Sequencing
Published in Science (American Association for the Advancement of Science) (10-03-2000)“…Neisseria meningitidis is a major cause of bacterial septicemia and meningitis. Sequence variation of surface-exposed proteins and cross-reactivity of the…”
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Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)‐mediated adhesion and invasion
Published in Cellular microbiology (01-03-2012)“…Summary NadA (N eisseria meningitidisadhesin A), a meningococcal surface protein, mediates adhesion to and invasion of human cells, an activity in which host…”
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Impact of preexisting memory to seasonal A / H 1 N 1 influenza virus on the immune response following vaccination against avian A / H 5 N 1 virus
Published in European journal of immunology (01-03-2013)“…Cross‐protection against divergent strains of influenza virus is an objective of various vaccination approaches. B cells cross‐neutralizing several influenza A…”
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Two years into reverse vaccinology
Published in Vaccine (30-01-2003)“…During the last century, several approaches have been used for the development of vaccines, going from the immunization with live-attenuated bacteria up to the…”
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Journal Article Conference Proceeding -
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Biotechnology and vaccines: application of functional genomics to Neisseria meningitidis and other bacterial pathogens
Published in Journal of biotechnology (30-09-2004)“…Since its introduction, vaccinology has been very effective in preventing infectious diseases. However, in several cases, the conventional approach to identify…”
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Journal Article Conference Proceeding -
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Mapping of the Neisseria meningitidis NadA Cell-Binding Site: Relevance of Predicted α-Helices in the NH 2 -Terminal and Dimeric Coiled-Coil Regions
Published in Journal of bacteriology (01-01-2011)“…NadA is a trimeric autotransporter protein of Neisseria meningitidis belonging to the group of oligomeric coiled-coil adhesins. It is implicated in the…”
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Mapping of the Neisseria meningitidis NadA Cell-Binding Site: Relevance of Predicted -Helices in the NH^sub 2^-Terminal and Dimeric Coiled-Coil Regions
Published in Journal of bacteriology (01-01-2011)“…NadA is a trimeric autotransporter protein of Neisseria meningitidis belonging to the group of oligomeric coiled-coil adhesins. It is implicated in the…”
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Mapping of the Neisseria meningitidis NadA cell-binding site: relevance of predicted {alpha}-helices in the NH2-terminal and dimeric coiled-coil regions
Published in Journal of bacteriology (01-01-2011)“…NadA is a trimeric autotransporter protein of Neisseria meningitidis belonging to the group of oligomeric coiled-coil adhesins. It is implicated in the…”
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