Search Results - "CANTELL, K"

N-glycosylation of human interferon-gamma: glycans at Asn-25 are critical for protease resistance by Sareneva, T, Pirhonen, J, Cantell, K, Julkunen, I

“…Human interferon-gamma (IFN-gamma) is a secretory, dimeric glycoprotein that forms a compact globular structure with potential N-linked glycosylation sites at…”
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Effect of interferon on glucose tolerance and insulin sensitivity by Koivisto, V. A., Pelkonen, R., Cantell, K.

“…Effect of interferon on glucose tolerance and insulin sensitivity. V A Koivisto , R Pelkonen and K Cantell Helsinki University Hospital, Second Department of…”
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Role of N-glycosylation in the synthesis, dimerization and secretion of human interferon-gamma by Sareneva, T, Pirhonen, J, Cantell, K, Kalkkinen, N, Julkunen, I

“…Human interferon-gamma (IFN-gamma) is a secretory glycoprotein, which has two potential N-linked glycosylation sites at positions Asn-25 and Asn-97 of its 143…”
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Effect of interferon on glucose tolerance and insulin sensitivity by KOIVISTO, V. A, PELKONEN, R, CANTELL, K

“…Many viral infections induce interferon (IFN) production and cause insulin resistance. To examine the causal relationship between IFN and insulin resistance,…”
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Natural human interferon-α2 is O-glycosylated by ADOLF, G. R, KALSNER, I, AHORN, H, MAURER-FOGY, I, CANTELL, K

“…Natural human interferon alpha 2 (IFN-alpha 2) was isolated from a preparation of partially purified human leucocyte IFN by monoclonal-antibody immunoaffinity…”
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Natural interferon alfa as maintenance therapy for small cell lung cancer by Mattson, K, Niiranen, A, Pyrhönen, S, Holsti, L R, Holsti, P, Kumpulainen, E, Cantell, K

“…We performed a 3-armed phase III study between 1982 and 1990 to evaluate low dose natural interferon alfa (nIFN-alpha) as a maintenance therapy in small cell…”
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Large-scale Production of Human Leukocyte Interferon Containing 108 Units per ml by Cantell, K, Hirvonen, Sinikka

“…Department of Virology Central Public Health Laboratory Helsinki 28, Finland A procedure is described by which human leukocyte interferon can be concentrated…”
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Clinical performance of natural human leukocyte interferon by Cantell, K

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Interferon maintenance therapy for small cell lung cancer: improvement in long-term survival by Mattson, K, Niiranen, A, Ruotsalainen, T, Maasilta, P, Halme, M, Pyrhönen, S, Kajanti, M, Mäntylä, M, Tamminen, K, Jekunen, A, Sarna, S, Cantell, K

“…Two hundred thirty-seven patients with small cell lung cancer (SCLC), who had responded to induction chemotherapy and radiotherapy, were randomly assigned to…”
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Large-scale production of human leukocyte interferon containing 10(8) units per ml by Cantell, K, Hirvonen, S

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Pharmacokinetics and toxicity of inhaled human natural interferon-beta in patients with lung cancer by Halme, M, Maasilta, P, Mattson, K, Cantell, K

“…Eight patients with a thoracic malignancy inhaled single doses of 3-100 x 10(6) IU of human natural interferon (IFN)-beta via a dosimeter-equipped jet…”
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Conjugation of interferon alpha to a humanized monoclonal antibody (HuBrE-3vl) enhances the selective localization and antitumor effects of interferon in breast cancer xenografts by OZZELLO, L, BLANK, E. W, DE ROSA, C. M, CERIANI, R. L, TÖLÖ, H, KAUPPINEN, H.-L, CANTELL, K

“…Human mammary carcinoma xenografts (MCF-7) growing in nude mice were treated with natural interferon alpha (n-IFN-alpha) alone or conjugated to a humanized…”
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Neurologic sequelae following interferon therapy of juvenile laryngeal papilloma by Vesikari, T, Nuutila, A, Cantell, K

“…Human leukocyte interferon at doses from 2 million units every two days to 3 million units daily was given to a 2-year-old boy for the treatment of recurrent…”
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Sensitivity of the Epstein-Barr Virus Transformed Human Lymphoid Cell Lines to Interferon by Adams, Alice, Strander, H, Cantell, K

“…* Department of Tumor Biology, Karolinska Institute Radiumhemmet, Karolinska Hospital, Stockholm 60, Sweden, and Department of Virology, Central Public Health…”
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Behavioral assessment of patients treated with alpha-interferon by Niiranen, A, Laaksonen, R, Iivanainen, M, Mattson, K, Färkkilä, M, Cantell, K

“…To document behavioral effects of interferon (IFN) with daily consecutive assessments we developed an easily administered procedure for bedside testing. It…”
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Alpha- and gamma-interferon inhibit plasminogen activator inhibitor-1 gene expression in human retinal pigment epithelial cells by Sirén, V, Immonen, I, Cantell, K, Vaheri, A

“…The effect of interferons IFN-alpha and IFN-gamma on the production of plasminogen activators (PAs) and plasminogen activator inhibitors (PAIs) was examined in…”
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Recombinant interferon gamma treatment in non-small cell lung cancer. Antitumour effect and cardiotoxicity by Mattson, K, Niiranen, A, Pyrhönen, S, Färkkilä, M, Cantell, K

“…Fifteen patients with previously untreated, inoperable non-small cell lung cancer were treated with r-IFN-gamma 2 mg/m2, on alternate days three times a week…”
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Human natural killer cell activity is augmented by interferon via recruitment of 'pre-NK' cells by Saksela, E, Timonen, T, Cantell, K

“…Contact with various cell-line targets increases the natural killer (NK) activity of human lymphocytes. Supernatants of such 20 h co-cultures augment the NK…”
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Human leukocyte interferon inhibits human chorionic gonadotropin stimulated testosterone production by porcine Leydig cells in culture by Orava, M, Cantell, K, Vihko, R

“…Pretreatment of primary porcine Leydig cell cultures with human leukocyte interferon suppressed the subsequent hCG-stimulated testosterone production in a…”
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Immune response to inactivated influenza virus vaccine: antibody reactivity with epidemic influenza B viruses of two highly distinct evolutionary lineages by Pyhälä, R, Kleemola, M, Kumpulainen, V, Vartiainen, E, Lappi, S, Pönkä, A, Cantell, K

“…Vaccination of adults (healthy female employees potentially capable of transmitting influenza to high-risk persons; n = 104) in autumn 1990 with a trivalent…”
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