Search Results - "CANPING JIANG"

A mechanistic study of Protein A chromatography resin lifetime by Jiang, Canping, Liu, Jing, Rubacha, Michael, Shukla, Abhinav A.

“…A mechanistic study into Protein A chromatographic resin lifetime limitations is presented. Binding and mass transport properties of two widely used…”
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Defining process design space for a hydrophobic interaction chromatography (HIC) purification step: Application of quality by design (QbD) principles by Jiang, Canping, Flansburg, Lisa, Ghose, Sanchayita, Jorjorian, Paul, Shukla, Abhinav A

“…The concept of design space has been taking root under the quality by design paradigm as a foundation of in‐process control strategies for biopharmaceutical…”
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Improved process analytical technology for protein a chromatography using predictive principal component analysis tools by Hou, Ying, Jiang, Canping, Shukla, Abhinav A, Cramer, Steven M

“…Protein A chromatography is widely employed for the capture and purification of antibodies and Fc‐fusion proteins. Due to the high cost of protein A resins,…”
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Defining process design space for monoclonal antibody cell culture by Abu-Absi, Susan Fugett, Yang, LiYing, Thompson, Patrick, Jiang, Canping, Kandula, Sunitha, Schilling, Bernhard, Shukla, Abhinav A

“…The concept of design space has been taking root as a foundation of in-process control strategies for biopharmaceutical manufacturing processes. During mapping…”
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Demonstration of Robust Host Cell Protein Clearance in Biopharmaceutical Downstream Processes by Shukla, Abhinav A., Jiang, Canping, Ma, Junfen, Rubacha, Michael, Flansburg, Lisa, Lee, Steven S.

“…Residual host cell protein impurities (HCPs) are a key component of biopharmaceutical process related impurities. These impurities need to be effectively…”
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Demonstrating β-glucan and yeast peptide clearance in biopharmaceutical downstream processes by Jiang, Canping, Scherfner, Sarah, Shukla, Abhinav A.

“…The use of yeast‐ and plant‐derived hydrolysates in cell culture production processes has sparked concerns over the potential immunogenicity risk posed by…”
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Presence of imidazole in loading buffer prevents formation of free radical in immobilized metal affinity chromatography and dramatically improves the recovery of herpes simplex virus type 1 gene therapy vectors by Jiang, Canping, Glorioso, Joseph C, Ataai, Mohammad

“…We have recently shown that immobilized metal affinity chromatography (IMAC) is an effective technique for purification of herpes simplex virus type 1 (HSV-1)…”
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Immobilized Cobalt Affinity Chromatography Provides a Novel, Efficient Method for Herpes Simplex Virus Type 1 Gene Vector Purification by CANPING JIANG, WECHUCK, James B, GOINS, William F, KRISKY, David M, WOLFE, Darren, ATAAI, Mohammad M, GLORIOSO, Joseph C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inactivation of herpes simplex type 1 gene vector on immobilized metal affinity chromatography: Oxidative damage by hydroxyl free radicals and its prevention by Jiang, Canping, Ataai, Mohammad, Ozuer, Ali, Krisky, David, Wechuck, James, Pornsuwan, Soraya, Pourarian, Fazard, Glorioso, Joseph C.

“…Metal catalyzed oxidation (MCO), which typically involves oxygen free radical generation, is an important pathway that leads to the deterioration of many…”
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Modulation of transmembrane pressure in manufacturing scale tangential flow filtration N‐1 perfusion seed culture by Karst, Daniel J., Ramer, Kevin, Hughes, Erik H., Jiang, Canping, Jacobs, Pieter J., Mitchelson, Fernie G.

“…Mammalian cells were grown to high density in a 3,000 L culture using perfusion with hollow fibers operated in a tangential flow filtration mode. The…”
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Demonstrating Delta b-glucan and yeast peptide clearance in biopharmaceutical downstream processes by Jiang, Canping, Scherfner, Sarah, Shukla, Abhinav A

“…The use of yeast- and plant-derived hydrolysates in cell culture production processes has sparked concerns over the potential immunogenicity risk posed by…”
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Erratum by Jiang, Canping, Scherfner, Sarah, Dick, Lawrence W., Mahon, David, Qiu, Difei, Cheng, Kuang‐Chuan, Shukla, Abhinav A.

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Erratum by Jiang, Canping, Scherfner, Sarah, Dick Jr, Lawrence W., Mahon, David, Qiu, Difei, Cheng, Kuang-Chuan, Shukla, Abhinav A.

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Erratum by Jiang, Canping, Scherfner, Sarah, Dick, Lawrence W., Mahon, David, Qiu, Difei, Cheng, Kuang‐Chuan, Shukla, Abhinav A.

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Demonstration of Robust Host Cell Protein Clearance in Biopharmaceutical Downstream Processes by Shukla, Abhinav A, Jiang, Canping, Ma, Junfen, Rubacha, Michael, Flansburg, Lisa, Lee, Steven S

“…Residual host cell protein impurities (HCPs) are a key component of biopharmaceutical process related impurities. These impurities need to be effectively…”
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Immobilized cobalt affinity purification for HSV-1 based gene therapy vectors by Jiang, Canping

“…Herpes simplex virus type 1 (HSV-1) is a promising vector for gene therapy applications. To be used as therapeutic agents, HSV-1 vectors must meet the…”
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Immobilized cobalt affinity purification for HSV-1 based gene therapy vectors by Jiang, Canping

“…Herpes simplex virus type 1 (HSV-1) is a promising vector for gene therapy applications. To be used as therapeutic agents, HSV-1 vectors must meet the…”
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794. Immobilized Cobalt Affinity Chromatography Provides a Novel, Efficient Method for HSV Gene Vector Purification by Jiang, Canping, Wechuck, James B, Goins, William F, Krisky, David M, Wolfe, Darren P, Ataai, Mohammad M, Glorioso, Joseph C

“…Herpes simplex virus type 1 (HSV-1) is a promising vector for gene therapy applications particularly to peripheral nerves, the natural site of virus latency…”
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