Search Results - "CANETE, Adela"
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Lenvatinib with etoposide plus ifosfamide in patients with refractory or relapsed osteosarcoma (ITCC-050): a multicentre, open-label, multicohort, phase 1/2 study
Published in The lancet oncology (01-09-2021)“…Tyrosine kinase inhibitors have shown activity in osteosarcoma and might enhance the efficacy of chemotherapy. We aimed to determine the recommended phase 2…”
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Comprehensive evaluation of context dependence of the prognostic impact of MYCN amplification in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project
Published in Pediatric blood & cancer (01-08-2019)“…Background MYCN amplification (MYCN‐A) is an established adverse prognostic factor in neuroblastoma. The extent to which the prognostic impact of MYCN‐A…”
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Scaling up and implementing the digital Survivorship Passport tool in routine clinical care – The European multidisciplinary PanCareSurPass project
Published in European journal of cancer (1990) (01-05-2024)“…Childhood cancer survivors (CCS), of whom there are about 500,000 living in Europe, are at an increased risk of developing health problems [1–6] and require…”
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Risk stratification of high‐risk metastatic neuroblastoma: A report from the HR‐NBL‐1/SIOPEN study
Published in Pediatric blood & cancer (01-11-2018)“…Background Risk stratification is crucial to treatment decision‐making in neuroblastoma. This study aimed to explore factors present at diagnosis affecting…”
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Excellent Outcome With Reduced Treatment in Infants With Nonmetastatic and Unresectable Neuroblastoma Without MYCN Amplification: Results of the Prospective INES 99.1
Published in Journal of clinical oncology (01-02-2011)“…To evaluate the efficacy of low-dose chemotherapy in infants with nonmetastatic and unresectable neuroblastoma (NB) without MYCN amplification. Infants with…”
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Poor Survival for Infants With MYCN-Amplified Metastatic Neuroblastoma Despite Intensified Treatment: The International Society of Paediatric Oncology European Neuroblastoma Experience
Published in Journal of clinical oncology (01-03-2009)“…To report the results of a prospective, nonrandomized European study on infants with neuroblastoma and MYCN gene amplification. Infants with neuroblastoma…”
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European recommendations for short-term surveillance of health problems in childhood, adolescent and young adult cancer survivors from the end of treatment to 5 years after diagnosis: a PanCare guideline
Published in Journal of cancer survivorship (04-12-2023)“…Abstract Purpose Childhood, adolescent and young adult (CAYA) cancer survivors require ongoing surveillance for health problems from the end of cancer…”
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Factors Influencing Implementation of the Survivorship Passport: The IT Perspective
Published in Studies in health technology and informatics (16-05-2022)“…Compared to the general population, childhood cancer survivors represent a vulnerable population as they are at increased risk of developing health problems,…”
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Hypermethylation of apoptotic genes as independent prognostic factor in neuroblastoma disease
Published in Molecular carcinogenesis (01-03-2011)“…Neuroblastoma (NB) is an embryonal tumour of neuroectodermal cells, and its prognosis is based on patient age at diagnosis, tumour stage and MYCN…”
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Vitronectin as a molecular player of the tumor microenvironment in neuroblastoma
Published in BMC cancer (22-05-2019)“…Vitronectin is a multifunctional glycoprotein known in several human tumors for its adhesive role in processes such as cell growth, angiogenesis and…”
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Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study
Published in Journal of cancer survivorship (28-11-2023)“…To identify barriers and facilitators for implementing the Survivorship Passport (SurPass) v2.0 in six long-term follow-up (LTFU) care centres in Europe…”
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Delving into the clinical impact of NETs in pediatric cancer
Published in Pediatric research (02-08-2024)“…Pediatric cancer, a complex and heterogeneous group of diseases, continues to challenge medical research and treatment strategies. Despite advances in…”
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Deletion of 11q in Neuroblastomas Drives Sensitivity to PARP Inhibition
Published in Clinical cancer research (15-11-2017)“…Despite advances in multimodal therapy, neuroblastomas with hemizygous deletion in chromosome 11q (20%-30%) undergo consecutive recurrences with poor outcome…”
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Advances in emerging drugs for the treatment of neuroblastoma
Published in Expert opinion on emerging drugs (02-01-2017)“…Neuroblastoma is the most common solid extracranial tumor of childhood. Outcome for children with high-risk neuroblastoma remains suboptimal. More than half of…”
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Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma
Published in Journal of clinical oncology (01-04-2018)“…Purpose Bevacizumab (BEV) is approved in more than 60 countries for use in adults with recurrent glioblastoma. We evaluated the addition of BEV to radiotherapy…”
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Staging childhood cancers in Europe: Application of the Toronto stage principles for neuroblastoma and Wilms tumour. The JARC pilot study
Published in Pediatric blood & cancer (01-09-2021)“…Background The ‘Toronto consensus principles and guidelines’ (TG) provided paediatric‐specific staging system affordable by population‐based cancer registries…”
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Interoperability Architecture for a Paediatric Oncology European Reference Network
Published in Studies in health technology and informatics (2016)“…With the Directive 2011/24/EU on patients' rights in cross-border healthcare and the related delegated decisions, the European Commission defined a legal…”
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Vitronectin Levels in the Plasma of Neuroblastoma Patients and Culture Media of 3D Models: A Prognostic Circulating Biomarker?
Published in International journal of molecular sciences (10-08-2024)“…Vitronectin is a glycoprotein present in plasma and the extracellular matrix that is implicated in cell migration. The high amount of vitronectin found in…”
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Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study
Published in Clinical cancer research (01-11-2023)“…Abstract Purpose: This phase Ib study defined the safety, MTD, and recommended phase II dose (RP2D) of regorafenib combined with vincristine and irinotecan…”
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High Oct4 expression: implications in the pathogenesis of neuroblastic tumours
Published in BMC cancer (03-01-2019)“…Neuroblastic tumours (NBTs) are paediatric solid tumours derived from embryonic neural crest cells which harbour their own cancer stem cells (CSC). There is…”
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