Search Results - "CANE, PATRICIA"

Analysis of Inactivation of SARS-CoV-2 by Specimen Transport Media, Nucleic Acid Extraction Reagents, Detergents, and Fixatives by Welch, Stephen R, Davies, Katherine A, Buczkowski, Hubert, Hettiarachchi, Nipunadi, Green, Nicole, Arnold, Ulrike, Jones, Matthew, Hannah, Matthew J, Evans, Reah, Burton, Christopher, Burton, Jane E, Guiver, Malcolm, Cane, Patricia A, Woodford, Neil, Bruce, Christine B, Roberts, Allen D G, Killip, Marian J

“…The COVID-19 pandemic has necessitated a multifaceted rapid response by the scientific community, bringing researchers, health officials, and industry together…”
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Vaccine Induced Herd Immunity for Control of Respiratory Syncytial Virus Disease in a Low-Income Country Setting by Kinyanjui, Timothy M, House, Thomas A, Kiti, Moses C, Cane, Patricia A, Nokes, David J, Medley, Graham F

“…Respiratory syncytial virus (RSV) is globally ubiquitous, and infection during the first six months of life is a major risk for severe disease and hospital…”
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The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya by Ochola, Rachel, Sande, Charles, Fegan, Gregory, Scott, Paul D, Medley, Graham F, Cane, Patricia A, Nokes, D James

“…Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants. The rate of decay of RSV-specific maternal antibodies…”
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The Source of Respiratory Syncytial Virus Infection In Infants: A Household Cohort Study In Rural Kenya by Munywoki, Patrick K., Koech, Dorothy C., Agoti, Charles N., Lewa, Clement, Cane, Patricia A., Medley, Graham F., Nokes, D. J.

“…Background. Respiratory syncytial virus (RSV) vaccine development for direct protection of young infants faces substantial obstacles. Assessing the potential…”
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Spread and Evolution of Respiratory Syncytial Virus A Genotype ON1, Coastal Kenya, 2010-2015 by Otieno, James R, Kamau, Everlyn M, Agoti, Charles N, Lewa, Clement, Otieno, Grieven, Bett, Ann, Ngama, Mwanajuma, Cane, Patricia A, Nokes, D James

“…In February 2012, the novel respiratory syncytial virus (RSV) group A, genotype ON1, was detected in Kilifi County, coastal Kenya. ON1 is characterized by a…”
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Local evolutionary patterns of human respiratory syncytial virus derived from whole-genome sequencing by Agoti, Charles N, Otieno, James R, Munywoki, Patrick K, Mwihuri, Alexander G, Cane, Patricia A, Nokes, D James, Kellam, Paul, Cotten, Matthew

“…Human respiratory syncytial virus (RSV) is associated with severe childhood respiratory infections. A clear description of local RSV molecular epidemiology,…”
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Presence, persistence and effects of pre-treatment HIV-1 drug resistance variants detected using next generation sequencing: A Retrospective longitudinal study from rural coastal Kenya by Hassan, Amin S, Bibby, David F, Mwaringa, Shalton M, Agutu, Clara A, Ndirangu, Kennedy K, Sanders, Eduard J, Cane, Patricia A, Mbisa, Jean L, Berkley, James A

“…The epidemiology of HIV-1 drug resistance (HIVDR) determined by Sanger capillary sequencing, has been widely studied. However, much less is known about HIVDR…”
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Frequent Asymptomatic Respiratory Syncytial Virus Infections During an Epidemic in a Rural Kenyan Household Cohort by Munywoki, Patrick K., Koech, Dorothy C., Agoti, Charles N., Bett, Ann, Cane, Patricia A., Medley, Graham F., Nokes, D. James

“…Background. The characteristics, determinants, and potential contribution to transmission of asymptomatic cases of respiratory syncytial virus (RSV) infection…”
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Rapid spread and diversification of respiratory syncytial virus genotype ON1, Kenya by Agoti, Charles N, Otieno, James R, Gitahi, Caroline W, Cane, Patricia A, Nokes, D James

“…Respiratory syncytial virus genotype ON1, which is characterized by a 72-nt duplication in the attachment protein gene, has been detected in >10 countries…”
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Viral Etiology of Severe Pneumonia Among Kenyan Infants and Children by Berkley, James A, Munywoki, Patrick, Ngama, Mwanajuma, Kazungu, Sidi, Abwao, John, Bett, Anne, Lassauniére, Ria, Kresfelder, Tina, Cane, Patricia A, Venter, Marietjie, Scott, J. Anthony G, Nokes, D. James

“…CONTEXT Pneumonia is the leading cause of childhood death in sub-Saharan Africa. Comparative estimates of the contribution of causative pathogens to the burden…”
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Incidence and Severity of Respiratory Syncytial Virus Pneumonia in Rural Kenyan Children Identified through Hospital Surveillance by Nokes, D. James, Ngama, Mwanajuma, Bett, Anne, Abwao, John, Munywoki, Patrick, English, Mike, Scott, J. Anthony G., Cane, Patricia A., Medley, Graham F.

“…Background.Although necessary for developing a rationale for vaccination, the burden of severe respiratory syncytial virus (RSV) disease in children in…”
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Proposal for Human Respiratory Syncytial Virus Nomenclature below the Species Level by Salimi, Vahid, Viegas, Mariana, Trento, Alfonsina, Agoti, Charles N, Anderson, Larry J, Avadhanula, Vasanthi, Bahl, Justin, Bont, Louis, Brister, J Rodney, Cane, Patricia A, Galiano, Mónica, Graham, Barney S, Hatcher, Eneida L, Hellferscee, Orienka, Henke, David M, Hirve, Siddhivinayak, Jackson, Sandra, Keyaerts, Els, Kragten-Tabatabaie, Leyla, Lindstrom, Stephen, Nauwelaers, Inne, Nokes, D James, Openshaw, Peter J, Peret, Teresa C, Piedra, Pedro A, Ramaekers, Kaat, Rector, Annabel, Trovão, Nídia Sequeira, von Gottberg, Anne, Zambon, Maria, Zhang, Wenqing, Williams, Thomas C, Barr, Ian G, Buchholz, Ursula J

“…Human respiratory syncytial virus (HRSV) is the leading viral cause of serious pediatric respiratory disease, and lifelong reinfections are common. Its 2 major…”
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Evidence of Self-Sustaining Drug Resistant HIV-1 Lineages Among Untreated Patients in the United Kingdom by Mbisa, Jean L., Fearnhill, Esther, Dunn, David T., Pillay, Deenan, Asboe, David, Cane, Patricia A.

“…Background. About 10% of new diagnoses of subtype B human immunodeficiency virus type 1 (HIV-1) in the United Kingdom are with viruses showing transmitted drug…”
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A large population sample of African HIV genomes from the 1980s reveals a reduction in subtype D over time associated with propensity for CXCR4 tropism by Grant, Heather E, Roy, Sunando, Williams, Rachel, Tutill, Helena, Ferns, Bridget, Cane, Patricia A, Carswell, J Wilson, Ssemwanga, Deogratius, Kaleebu, Pontiano, Breuer, Judith, Leigh Brown, Andrew J

“…We present 109 near full-length HIV genomes amplified from blood serum samples obtained during early 1986 from across Uganda, which to our knowledge is the…”
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Continuous Invasion by Respiratory Viruses Observed in Rural Households During a Respiratory Syncytial Virus Seasonal Outbreak in Coastal Kenya by Munywoki, Patrick K, Koech, Dorothy C, Agoti, Charles N, Cane, Patricia A, Medley, Graham F, Nokes, D James

“…This is the first household study of multiple respiratory viruses in a low-income setting that used intensive sampling regardless of symptoms. There was a…”
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Successive Respiratory Syncytial Virus Epidemics in Local Populations Arise from Multiple Variant Introductions, Providing Insights into Virus Persistence by Agoti, Charles N, Otieno, James R, Ngama, Mwanajuma, Mwihuri, Alexander G, Medley, Graham F, Cane, Patricia A, Nokes, D James

“…Respiratory syncytial virus (RSV) is a global respiratory pathogen of humans, with infection occurring characteristically as recurrent seasonal epidemics…”
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Virucidal efficacy of guanidine-free inactivants and rapid test buffers against SARS-CoV-2 by Davies, Katherine, Arnold, Ulrike, Buczkowski, Hubert, Burton, Christopher, Welch, Stephen R., Green, Nicole, Strachan, Rhea, Beetar-King, Tracy, Spencer, Peter, Hettiarachchi, Nipunadi, Hannah, Matthew J., Jones, Matthew, Cane, Patricia A., Bruce, Christine B., Woodford, Neil, Roberts, Allen D. G., Killip, Marian J.

“…A pathogen inactivation step during collection or processing of clinical samples has the potential to reduce infectious risks associated with diagnostic…”
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Genomic analysis of respiratory syncytial virus infections in households and utility in inferring who infects the infant by Agoti, Charles N., Phan, My V. T., Munywoki, Patrick K., Githinji, George, Medley, Graham F., Cane, Patricia A., Kellam, Paul, Cotten, Matthew, Nokes, D. James

“…Infants (under 1-year-old) are at most risk of life threatening respiratory syncytial virus (RSV) disease. RSV epidemiological data alone has been insufficient…”
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Molecular Evolutionary Dynamics of Respiratory Syncytial Virus Group A in Recurrent Epidemics in Coastal Kenya by Otieno, James R, Agoti, Charles N, Gitahi, Caroline W, Bett, Ann, Ngama, Mwanajuma, Medley, Graham F, Cane, Patricia A, Nokes, D James

“…The characteristic recurrent epidemics of human respiratory syncytial virus (RSV) within communities may result from the genetic variability of the virus and…”
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HIV-1 pol gene variation is sufficient for reconstruction of transmissions in the era of antiretroviral therapy by HUE, Stéphane, CLEWLEY, Jonathan P, CANE, Patricia A, PILLAY, Deenan

“…We wished to assess the potential of using HIV-1 pol gene for the identification of transmissions events by phylogenetic means in the era of antiretroviral…”
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