Search Results - "CANDURI, F"

REVIEW-ARTICLE Bioinformatics: an overview and its applications by Diniz, W J S, Canduri, F

“…Technological advancements in recent years have promoted a marked progress in understanding the genetic basis of phenotypes. In line with these advances,…”
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Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell- and apicomplexan parasite-mediated diseases by Silva, R G, Nunes, J E S, Canduri, F, Borges, J C, Gava, L M, Moreno, F B, Basso, L A, Santos, D S

“…Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphorolysis of nucleosides and deoxynucleosides, generating ribose 1-phosphate and the purine…”
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Molecular Model for the Binary Complex of Uropepsin and Pepstatin by de Azevedo, Walter F., Canduri, Fernanda, Fadel, Valmir, Teodoro, Lívia G.V.L., Hial, Valdemar, Gomes, Roseli A.S.

“…The three-dimensional structure of human uropepsin complexed with pepstatin has been modelled using human pepsin as a template. Uropepsin is an aspartic…”
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Molecular modeling and small angle X-ray scattering studies of Hoplosternum littorale cathodic haemoglobin by Peres, P., Lombardi, F.R., dos Santos, G.C., Olivieri, J.R., Canduri, F., Bonilla-Rodriguez, G.O., de Azevedo, W.F.

“…Considerable interest is currently focused on fish haemoglobins in order to identify the structural basis for their diversity of functional behavior…”
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Crystal structure of piratoxin-I : A calcium-independent, myotoxic phospholipase A2-HOMOLOGUE from Bothrops pirajai venom by DE AZEVEDO, W. F, WARD, R. J, CANDURI, F, SOARES, A, GIGLIO, J. R, ARNI, R. K

“…The crystal structure of Piratoxin-I (PrTX-I) a Lys49 homologue isolated from the venom of Bothrops pirajai has been determined and refined at 2.8 A to a…”
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Structure of human uropepsin at 2.45 Å resolution by Canduri, Fernanda, Teodoro, Lívia G. V. L., Fadel, Valmir, Lorenzi, Carla C. B., Hial, Valdemar, Gomes, Roseli A. S., Neto, João Ruggiero, De Azevedo Jr, Walter F.

“…The molecular structure of human uropepsin, an aspartic proteinase from the urine produced in the form of pepsinogen A in the gastric mucosa, has been…”
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Crystallization and preliminary X-ray diffraction analysis of a eumenine mastoparan toxin: a new class of mast-cell degranulating peptide in the wasp venom by Canduri, F., Delatorre, P., Fadel, V., Lorenzi, C. C. B., Pereira, J. H., Olivieri, J. R., Ruggiero Neto, J., Konno, K., Palma, M. S., Yamane, T., De Azevedo Jr, W. F.

“…Mastoparans are tetradecapeptides found to be the major component of vespid venoms. A mastoparan toxin isolated from the venom of Anterhynchium flavomarginatum…”
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Structural bioinformatics study of cyclin-dependent kinases complexed with inhibitors by Canduri, F., Silveira, N. J. F. da, Camera Jr, J. C., Azevedo Jr, W. F. de

“…The present work describes molecular models for the binary complexes CDK9, CDK5 and CDK1 complexed with Flavopiridol and Roscovitine. These structural models…”
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Preliminary cryocrystallography analysis of an eumenine mastoparan toxin isolated from the venom of the wasp Anterhynchium flavomarginatum micado by Delatorre, P, Olivieri, J R, Ruggiero Neto, J, Lorenzi, C C, Canduri, F, Fadel, V, Konno, K, Palma, M S, Yamane, T, de Azevedo, Jr, W F

“…Mastoparans are tetradecapeptides found to be the major component of vespid venoms. These peptides present a wide spectrum of biological activities, such as…”
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Purification, crystallization and Patterson search of haemoglobin IV from the armoured catfish Liposarcus anisitsi by Delatorre, P., Smarra, A. L. S., Fadel, V., Canduri, F., Dellamano, M., Bonilla-Rodriguez, G. O., De Azevedo Jr, W. F.

“…Considerable interest is currently focused on fish haemoglobins in order to identify the structural basis for their diversity of functional behaviour. The…”
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Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis by Oliveira, Jaim S., Pereira, José H., Canduri, Fernanda, Rodrigues, Nathália C., de Souza, Osmar N., de Azevedo, Walter F., Basso, Luiz A., Santos, Diógenes S.

“…An understanding of isoniazid (INH) drug resistance mechanism in Mycobacterium tuberculosis should provide significant insight for the development of newer…”
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Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol by Filgueira de Azevedo, Walter, Canduri, Fernanda, Freitas da Silveira, Nelson José

“…Flavopiridol has been shown to potently inhibit CDK1 and 2 (cyclin-dependent kinases 1 and 2) and most recently it has been found that it also inhibits CDK9…”
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Molecular models of cyclin-dependent kinase 1 complexed with inhibitors by Canduri, Fernanda, Uchoa, Hugo Brandão, de Azevedo, Walter Filgueira

“…Roscovitine and flavopiridol have been shown to potently inhibit cyclin-dependent kinase 1 and 2 (CDK1 and 2). The structures of CDK2 complexed with…”
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Crystallization, preliminary X-ray analysis and molecular-replacement solution of the carboxy form of haemoglobin I from the fish Brycon cephalus by Honda, R. T., Delatorre, P., Fadel, V., Canduri, F., Dellamano, M., De Azevedo Jr, W. F., Bonilla-Rodriguez, G. O.

“…Haemoglobin, the `honorary enzyme' [Brunori (1999), Trends Biochem. Sci.24, 158–161], constitutes a prime prototype for allosteric models. Here, the…”
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Structural bioinformatics study of cyclin-dependent kinases complexed with inhibitors by Canduri, Fernanda, Da Silveira, Nelson José Freitas, Câmera Junior, João Carlos, De Azevedo Júnior, Walter Filgueira

“…The present work describes molecular models for the binary complexes CDK9, CDK5 andCDK1 complexed with Flavopiridol and Roscovitine. These structural models…”
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Parmodel: a web server for automated comparative modeling of proteins by Uchôa, Hugo Brandão, Jorge, Guilherme Eberhart, Freitas Da Silveira, Nelson José, Camera, João Carlos, Canduri, Fernanda, De Azevedo, Walter Filgueira

“…Parmodel is a web server for automated comparative modeling and evaluation of protein structures. The aim of this tool is to help inexperienced users to…”
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How C-Terminal Carboxyamidation Alters the Biological Activity of Peptides from the Venom of the Eumenine Solitary Wasp by Sforça, Maurício L, Oyama, Sérgio, Canduri, Fernanda, Lorenzi, Carla C. B, Pertinhez, Thelma A, Konno, Katsuhiro, Souza, Bibiana M, Palma, Mário S, Ruggiero Neto, J, Azevedo, Walter F, Spisni, Alberto

“…Inflammatory peptides display different types of post-transcriptional modifications, such as C-terminal amidation, that alter their biological activity. Here…”
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Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid by Pereira, José Henrique, De Oliveira, Jaim Simões, Canduri, Fernanda, Dias, Marcio Vinicius Bertacine, Palma, Mário Sérgio, Basso, Luiz Augusto, Santos, Diógenes Santiago, De Azevedo Jr, Walter Filgueira

“…Tuberculosis made a resurgence in the mid‐1980s and now kills approximately 3 million people a year. The re‐emergence of tuberculosis as a public health…”
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New catalytic mechanism for human purine nucleoside phosphorylase by Canduri, Fernanda, Fadel, Valmir, Basso, Luiz Augusto, Palma, Mário Sérgio, Santos, Diógenes Santiago, de Azevedo, Walter Filgueira

“…Human purine nucleoside phosphorylase has been submitted to intensive structure-based design of inhibitors, most of them using low-resolution structures of…”
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Molecular model of cyclin-dependent kinase 5 complexed with roscovitine by de Azevedo, Walter Filgueira, Tadeu Gaspar, Renato, Canduri, Fernanda, Carlos Camera, João, José Freitas da Silveira, Nelson

“…Here is described a structural model for the binary complex CDK5–roscovitine. Roscovitine has been shown to potently inhibit cyclin-dependent kinases 1, 2 and…”
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