Search Results - "CAMPANINI, N"

Primary resistance to osimertinib due to SCLC transformation: Issue of T790M determination on liquid re-biopsy by Minari, R., Bordi, P., Del Re, M., Facchinetti, F., Mazzoni, F., Barbieri, F., Camerini, A., Comin, C.E., Gnetti, L., Azzoni, C., Nizzoli, R., Bortesi, B., Rofi, E., Petreni, P., Campanini, N., Rossi, G., Danesi, R., Tiseo, M.

“…•Liquid biopsy alone could underestimate coexistence of resistance mechanisms.•T790M plasma levels should be taken into account for clinical decisions.•Low…”
Get full text

Grading the neuroendocrine tumors of the lung: an evidence-based proposal by Rindi, G, Klersy, C, Inzani, F, Fellegara, G, Ampollini, L, Ardizzoni, A, Campanini, N, Carbognani, P, De Pas, T M, Galetta, D, Granone, P L, Righi, L, Rusca, M, Spaggiari, L, Tiseo, M, Viale, G, Volante, M, Papotti, M, Pelosi, G

“…Lung neuroendocrine tumors are catalogued in four categories by the World Health Organization (WHO 2004) classification. Its reproducibility and prognostic…”
Get full text

Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts by Chiu, M, Tardito, S, Pillozzi, S, Arcangeli, A, Armento, A, Uggeri, J, Missale, G, Bianchi, M G, Barilli, A, Dall'Asta, V, Campanini, N, Silini, E M, Fuchs, J, Armeanu-Ebinger, S, Bussolati, O

“…Background: A subset of human hepatocellular carcinomas (HCC) exhibit mutations of β -catenin gene CTNNB1 and overexpress Glutamine synthetase (GS). The CTNNB1…”
Get full text

ERCC1/BRCA1 expression and gene polymorphisms as prognostic and predictive factors in advanced NSCLC treated with or without cisplatin by Tiseo, M, Bordi, P, Bortesi, B, Boni, L, Boni, C, Baldini, E, Grossi, F, Recchia, F, Zanelli, F, Fontanini, G, Naldi, N, Campanini, N, Azzoni, C, Bordi, C, Ardizzoni, A

“…Background: The FAST was a factorial trial in first-line treatment of advanced non-small-cell lung cancer (NSCLC), addressing the role of replacing cisplatin…”
Get full text

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo by Storti, P, Marchica, V, Airoldi, I, Donofrio, G, Fiorini, E, Ferri, V, Guasco, D, Todoerti, K, Silbermann, R, Anderson, J L, Zhao, W, Agnelli, L, Bolzoni, M, Martella, E, Mancini, C, Campanini, N, Noonan, D M, Petronini, P G, Neri, A, Aversa, F, Roodman, G D, Giuliani, N

“…Galectin-1 (Gal-1) is involved in tumoral angiogenesis, hypoxia and metastases. Actually the Gal-1 expression profile in multiple myeloma (MM) patients and its…”
Get full text

Ghrelin Protects Against Ethanol-Induced Gastric Ulcers in Rats: Studies on the Mechanisms of Action by Sibilia, V, Rindi, G, Pagani, F, Rapetti, D, Locatelli, V, Torsello, A, Campanini, N, Deghenghi, R, Netti, C

“…Ghrelin, the endogenous ligand for GH secretagogue receptors, has been reported to influence acid gastric secretion and motility, but its potential…”
Get full text

Functional HRD by RAD51 identifies BRCA1 VUS associated with loss of gene function and response to DNA-damaging agents by Casartelli, C., Tommasi, C., Lazzarin, A., Corianò, M., Tornali, C., Serra, O., Campanini, N., Gutiérrez-Enríquez, S., Sikokis, A., Zanoni, D., Minari, R., Bortesi, B., Michiara, M., Boggiani, D., Uliana, V., Llop-Guevara, A., Serra, V., Musolino, A., Pellegrino, B.

Get full text

Central ghrelin gastroprotection involves nitric oxide/prostaglandin cross‐talk by Sibilia, V, Pagani, F, Rindi, G, Lattuada, N, Rapetti, D, De Luca, V, Campanini, N, Bulgarelli, I, Locatelli, V, Guidobono, F, Netti, C

“…Background and purpose: Ghrelin, a gut‐brain peptide, is considered a gastroprotective factor in gastric mucosa. We investigated the role of prostaglandins…”
Get full text

Alternative academic approaches for testing homologous recombination deficiency in ovarian cancer in the MITO16A/MaNGO-OV2 trial by Capoluongo, E.D., Pellegrino, B., Arenare, L., Califano, D., Scambia, G., Beltrame, L., Serra, V., Scaglione, G.L., Spina, A., Cecere, S.C., De Cecio, R., Normanno, N., Colombo, N., Lorusso, D., Russo, D., Nardelli, C., D’Incalci, M., Llop-Guevara, A., Pisano, C., Baldassarre, G., Mezzanzanica, D., Artioli, G., Setaro, M., Tasca, G., Roma, C., Campanini, N., Cinieri, S., Sergi, A., Musolino, A., Perrone, F., Chiodini, P., Marchini, S., Pignata, S.

“…The detection of homologous recombination deficiency (HRD) can identify patients who are more responsive to platinum and poly ADP ribose polymerase inhibitors…”
Get full text

Prognostic impact of interval breast cancer detection in women with pT1a N0M0 breast cancer with HER2-positive status: Results from a multicentre population-based cancer registry study by Musolino, A., Falcini, F., Sikokis, A., Boggiani, D., Rimanti, A., Pellegrino, B., Silini, E.M., Campanini, N., Barbieri, E., Zamagni, C., Degli Esposti, R., Cortesi, L., Bisagni, G., Cavanna, L., Frassoldati, A., Sgargi, P., Michiara, M.

“…Although human epidermal growth factor receptor 2 (HER2) overexpression is associated with poor prognosis, patients (pts) with pT1a N0M0 breast cancers (BCs)…”
Get full text

Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets by Capurso, G, Lattimore, S, Crnogorac-Jurcevic, T, Panzuto, F, Milione, M, Bhakta, V, Campanini, N, Swift, S M, Bordi, C, Fave, G Delle, Lemoine, N R

“…The intrinsic nature of tumour behaviour (stable vs progressive) and the presence of liver metastases are key factors in determining the outcome of patients…”
Get full text

Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy by Negri, F V, Campanini, N, Camisa, R, Pucci, F, Bui, S, Ceccon, G, Martinelli, R, Fumagalli, M, Losardo, P L, Crafa, P, Bordi, C, Cascinu, S, Ardizzoni, A

“…We analysed the expression of microsatellite instability, p53, p21, vascular endothelial growth factor and thymidylate synthase (TS) in pretreatment biopsy…”
Get full text

The anti-tumoral effect of lenalidomide is increased in vivo by hypoxia-inducible factor (HIF)-1  inhibition in myeloma cells by Storti, P., Toscani, D., Airoldi, I., Marchica, V., Maiga, S., Bolzoni, M., Fiorini, E., Campanini, N., Martella, E., Mancini, C., Guasco, D., Ferri, V., Donofrio, G., Aversa, F., Amiot, M., Giuliani, N.

Get full text

RASSF1A promoter methylation and 3p21.3 loss of heterozygosity are features of foregut, but not midgut and hindgut, malignant endocrine tumours by Pizzi, S, Azzoni, C, Bottarelli, L, Campanini, N, D'Adda, T, Pasquali, C, Rossi, G, Rindi, G, Bordi, C

“…The Ras‐association domain family 1A (RASSF1A) tumour suppressor gene is inactivated in a variety of solid tumours, usually by epigenetic silencing of the…”
Get full text

821 GLUTAMINE SYNTHETASE (GS) IMMUNOREACTIVITY CORRELATES WITH PATHOLOGICAL FEATURES OF HCC AND PREDICTS TUMOR-SPECIFIC SURVIVAL AFTER RFA ABLATION by Silini, E.M, Bello, B. Dal, Rosa, L.L, Campanini, N, Tinelli, C, D'Ambrosio, G, Rossi, S

Get full text

C-kit protein expression in Wilms' tumour: An immunohistochemical study by Giordano, G, Campanini, N, Rocco, A, Donofrio, V, Bertolini, P, Falleti, J, Pettinato, G

“…Abstract Aim The use of a non-toxic tyrosine kinase receptor inhibitor, Imatinib Mesylate (IM), has become an ever-more common therapeutic alternative in some…”
Get full text

Somatostatin receptor subtypes mediate contractility on human colonic smooth muscle cells by Corleto, V. D., Severi, C., Romano, G., Tattoli, I., Weber, H. C., Stridsberg, M., Rindi, G., Campanini, N., Tomassoni, F., Pagotto, U., Coy, D. H., Jensen, R. T., Delle Fave, G.

“…This study demonstrates the expression of functional somatostatin receptor (sstr) subtypes in human circular and longitudinal colonic smooth muscle cells…”
Get full text

Optimisation of isolation of richly pure and homogeneous primary human colonic smooth muscle cells by Tattoli, I., Corleto, V.D., Taffuri, M., Campanini, N., Rindi, G., Caprilli, R., Delle Fave, G., Severi, C.

“…Background. Inherent properties of gastrointestinal smooth muscle can be assessed using isolated cell suspensions. Currently available isolation techniques,…”
Get full text

575P Impact of immunological alterations and post-operative biomarkers on long-term outcomes in patients with locally advanced rectal cancer: Results from the STAR-01 study cohort by Negri, F., Gnetti, L., Bottarelli, L., Campanini, N., Negru, M.E., Tamberi, S., Bergamo, F., Frisinghelli, M., Masi, G., Chiaulon, G., Tagliagambe, A., Siena, S., Petric, M., Morabito, A., Frassineti, G.L., Corsi, D.C., Rimassa, L., G.L. de'Angelis, Boni, L., Aschele, C.

Get full text

452P Predicting response to bevacizumab in colorectal cancer by integrating radiomics to clinical and genomic features by Milanese, G., Maddalo, M., Leo, L., Lecchini, M., Bottarelli, L., Gnetti, L., Campanini, N., Pedrazzi, G., Azzoni, C., Bozzetti, C., Zavani, A., Caruana, P., Silini, E.M., Sverzellati, N., Negri, F.

Get full text