Search Results - "CAMORS, Emmanuel"

Dual ablation of the RyR2‐Ser2808 and RyR2‐Ser2814 sites increases propensity for pro‐arrhythmic spontaneous Ca2+ releases by Janicek, Radoslav, Camors, Emmanuel M., Potenza, Duilio M., Fernandez‐Tenorio, Miguel, Zhao, Yanting, Dooge, Holly C., Loaiza, Randall, Alvarado, Francisco J., Egger, Marcel, Valdivia, Hector H., Niggli, Ernst

“…During exercise or stress, the sympathetic system stimulates cardiac contractility via β‐adrenergic receptor (β‐AR) activation, resulting in phosphorylation of…”
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Dual ablation of the RyR2-Ser2808 and RyR2-Ser2814 sites increases propensity for pro-arrhythmic spontaneous Ca 2+ releases by Janicek, Radoslav, Camors, Emmanuel M, Potenza, Duilio M, Fernandez-Tenorio, Miguel, Zhao, Yanting, Dooge, Holly C, Loaiza, Randall, Alvarado, Francisco J, Egger, Marcel, Valdivia, Hector H, Niggli, Ernst

“…During exercise or stress, the sympathetic system stimulates cardiac contractility via β-adrenergic receptor (β-AR) activation, resulting in phosphorylation of…”
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Progressive Reduction in Right Ventricular Contractile Function Attributable to Altered Actin Expression in an Aging Mouse Model of Arrhythmogenic Cardiomyopathy by Camors, Emmanuel M., Roth, Alyson H., Alef, Joseph R., Sullivan, Ryan D., Johnson, Jason N., Purevjav, Enkhsaikhan, Towbin, Jeffrey A.

“…Arrhythmogenic cardiomyopathy (ACM) is an inherited genetic disorder of desmosomal dysfunction, and PKP2 (plakophilin-2) has been reported to be the most…”
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Kinetics of FKBP12.6 Binding to Ryanodine Receptors in Permeabilized Cardiac Myocytes and Effects on Ca Sparks by Guo, Tao, Cornea, Razvan L, Huke, Sabine, Camors, Emmanuel, Yang, Yi, Picht, Eckard, Fruen, Bradley R, Bers, Donald M

“…RATIONALE:FK506-binding proteins FKBP12.6 and FKBP12 are associated with cardiac ryanodine receptors (RyR2), and cAMP-dependent protein kinase A…”
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CaMKII regulation of cardiac ryanodine receptors and inositol triphosphate receptors by Camors, Emmanuel, Valdivia, Héctor H

“…Ryanodine receptors (RyRs) and inositol triphosphate receptors (InsP3Rs) are structurally related intracellular calcium release channels that participate in…”
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Early Lethality Due to a Novel Desmoplakin Variant Causing Infantile Epidermolysis Bullosa Simplex With Fragile Skin, Aplasia Cutis Congenita, and Arrhythmogenic Cardiomyopathy by Camors, Emmanuel M., Purevjav, Enkhsaikhan, Jefferies, John L., Saffitz, Jeffrey E., Gong, Nan, Ryan, Thomas D., Lucky, Anne W., Taylor, Michael D., Sullivan, Lisa M., Mestroni, Luisa, Towbin, Jeffrey A.

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Altered Contractile Response due to Increased β3-Adrenoceptor Stimulation in Diabetic Cardiomyopathy by Amour, Julien, Loyer, Xavier, Le Guen, Morgan, Mabrouk, Nejma, David, Jean-Stéphane, Camors, Emmanuel, Carusio, Nunzia, Vivien, Benoît, Andriantsitohaina, Ramaroson, Heymes, Christophe, Riou, Bruno

“…Background In the diabetic heart, the positive inotropic response to beta-adrenoceptor stimulation is altered and beta1 and beta2 adrenoceptors are…”
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Abstract 15846: Impaired Contraction and High Susceptibility to Arrhythmias in a Mouse Model of Desmoplakin-Mediated Arrhythmogenic Cardiomyopathy by Camors, Emmanuel M, Orgil, Buyan-Ochir, Alberson, Neely, Purevjav, Enkhsaikhan, Towbin, Jeffrey A

“…Abstract only Introduction: Desmoplakin (DSP) is a key protein for cardiac myocyte cell-to-cell adhesion that connects the desmosomes present in intercalated…”
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Progressive Reduction in Right Ventricular Contractile Function Due to Altered Actin Expression in an Aging Mouse Model of Arrhythmogenic Cardiomyopathy by Camors, Emmanuel M., Roth, Alyson H., Alef, Joseph R., Sullivan, Ryan D., Johnson, Jason N., Purevjav, Enkhsaikhan, Towbin, Jeffrey A.

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Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete β-adrenergic response by Potenza, Duilio M, Janicek, Radoslav, Fernandez-Tenorio, Miguel, Camors, Emmanuel, Ramos-Mondragón, Roberto, Valdivia, Héctor H, Niggli, Ernst

“…During physical exercise or stress, the sympathetic system stimulates cardiac contractility via β-adrenergic receptor (β-AR) activation, resulting in protein…”
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Ankyrin-B reduction enhances Ca spark-mediated SR Ca release promoting cardiac myocyte arrhythmic activity by Camors, Emmanuel, Mohler, Peter J, Bers, Donald M, Despa, Sanda

“…Abstract Ankyrin-B (AnkB) loss-of-function may cause ventricular arrhythmias and sudden cardiac death in humans. Cardiac myocytes from AnkB heterozygous mice…”
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Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress Than Ventricular Myocytes From Mice With Catecholaminergic Polymorphic Ventricular Tachycardia by Willis, B Cicero, Pandit, Sandeep V, Ponce-Balbuena, Daniela, Zarzoso, Manuel, Guerrero-Serna, Guadalupe, Limbu, Bijay, Deo, Makarand, Camors, Emmanuel, Ramirez, Rafael J, Mironov, Sergey, Herron, Todd J, Valdivia, Héctor H, Jalife, José

“…BACKGROUND—In catecholaminergic polymorphic ventricular tachycardia (CPVT), cardiac Purkinje cells (PCs) appear more susceptible to Ca dysfunction than…”
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Ablation of two Major Phosphorylation Sites in RyR2 Alter Sarcoplamic Reticulum Calcium Handling and Increases the Propensity to Atrial Fibrillation by Ramos Mondragon, Roberto, Camors, Emmanuel M., Bao, Yangyang, Willis, Cicero B., Valdivia, Carmen, Isom, Lori, Jalife, Jose, Valdivia, Hector H.

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Ablation of Major PKA and/or Camkii Phosphorylation Sites in the RyR2 Channel Differentially Affects the Susceptibility of Mice to Vagotonic Atrial Fibrillation by Ramos Mondragón, Roberto, Camors, Emmanuel, Powers, Patricia P., Valdivia, Héctor H.

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Preventing RyR2-S2808 and RyR2-S2814 Phosphorylation does not Alter the β-Adrenergic Response of Mouse Hearts by Camors, Emmanuel, Loaiza, Randall, Alvarado, Francisco, Zhao, Yanting, Powers, Patricia, Valdivia, Hector H.

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Increased neuronal nitric oxide synthase-derived NO production in the failing human heart by Damy, Thibaud, Ratajczak, Philippe, Shah, Ajay M, Camors, Emmanuel, Marty, Isabelle, Hasenfuss, Gerd, Marotte, Françoise, Samuel, Jane-Lise, Heymes, Christophe

“…Experimental data suggest that nitric oxide (NO) generated from neuronal NO synthase (nNOS) modulates the myocardial inotropic state. To assess the…”
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Annexins and Ca2+ handling in the heart by CAMORS, Emmanuel, MONCEAU, Virginie, CHARLEMAGNE, Daniéle

“…Annexins are a family of 13 proteins known to bind phospholipids (PL) in a Ca(2+)-dependent way. They are ubiquitous proteins and share a similar structure…”
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Annexins and Ca handling in the heart by CAMORS, E, MONCEAU, V, CHARLEMAGNE, D

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Abstract 19322: Cardiac Function and Beta-Adrenergic Response in Mice with Genetic Ablation of Two Major Phosphorylation Sites in the Cardiac Ryanodine Receptor by Camors, Emmanuel, Loaiza, Randall, Alvarado, Francisco, Powers, Patricia, Valdivia, Héctor H

“…Abstract only Despite intensive research, the functional consequences of cardiac ryanodine receptor (RyR2) phosphorylation remain highly controversial. Two…”
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Altered contractile response due to increased β3-adrenoceptor stimulation in diabetic cardiomyopathy : The role of nitric oxide synthase 1-derived nitric oxide by AMOUR, Julien, LOYER, Xavier, RIOU, Bruno, LE GUEN, Morgan, MABROUK, Nejma, DAVID, Jean-Stéphane, CAMORS, Emmanuel, CARUSIO, Nunzia, VIVIEN, Benoit, ANDRIANTSITOHAINA, Ramaroson, HEYMES, Christophe

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