Search Results - "CAMBY, ISABELLE"
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Galectins as modulators of tumor progression in head and neck squamous cell carcinomas
Published in Head & neck (01-09-2007)“…Head and neck squamous cell carcinomas (HNSCCs) remain a significant cause of morbidity worldwide. Biological therapies able to induce and/or upregulate…”
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2
Anti-galectin compounds as potential anti-cancer drugs
Published in Current medicinal chemistry (01-12-2006)“…Galectins form a family of carbohydrate-binding proteins defined by their affinity for beta-galactosides containing glycoconjugates. The carbohydrate…”
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3
Galectin 7 (p53-induced gene 1): a new prognostic predictor of recurrence and survival in stage IV hypopharyngeal cancer
Published in Annals of surgical oncology (01-07-2006)“…Eighty percent of hypopharyngeal squamous cell carcinoma patients have advanced stages (III and IV) of the disease, and biological markers are required to…”
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Galectins Are Differentially Expressed in Supratentorial Pilocytic Astrocytomas, Astrocytomas, Anaplastic Astrocytomas and Glioblastomas, and Significantly Modulate Tumor Astrocyte Migration
Published in Brain pathology (Zurich, Switzerland) (01-01-2001)“…Galectins, a family of mammalian lectins with specificity to β‐galactosides, are involved in growth‐regulatory mechanisms and cell adhesion. A relationship is…”
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Molecular characterization of cell substratum attachments in human glial tumors relates to prognostic features
Published in Glia (01-12-2001)“…Glioma cell attachments to substratum play crucial roles in the invasion by glioma cells of normal brain tissue. These attachments are mediated through…”
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v-Src accelerates spontaneous motility via phosphoinositide 3-kinase, phospholipase C and phospholipase D, but abrogates chemotaxis in Rat-1 and MDCK cells
Published in Journal of cell science (15-09-2004)“…In Rat-1 fibroblasts, v-Src causes a profound remodelling of cortical actin cytoskeleton. This transformation includes membrane ruffling, a hallmark of the…”
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Galectin-1: a small protein with major functions
Published in Glycobiology (Oxford) (01-11-2006)“…Galectins are a family of carbohydrate-binding proteins with an affinity for β-galactosides. Galectin-1 (Gal-1) is differentially expressed by various normal…”
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Gastrin induces over-expression of genes involved in human U373 glioblastoma cell migration
Published in Oncogene (25-10-2001)“…Astrocytic tumors are the most common and the most malignant primary tumors of the central nervous system. We had previously observed that gastrin could…”
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C-terminal heptapeptide of gastrin inhibits astrocytomas motility by interacting with a new gastrin binding site
Published in The Journal of pharmacology and experimental therapeutics (01-07-2002)“…It is well known that the amidated C-terminal part of gastrin is crucial for its interaction with the classical seven transmembrane domain receptors CCK-1 or…”
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10
Galectins and cancer
Published in BBA - General Subjects (19-09-2002)“…The galectins are a family of proteins that are distributed widely in all living organisms. All of them share galactose-specificity. At present, 14 members of…”
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Book Review Journal Article -
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Galectin-1 Is Implicated in the Protein Kinase C ε/Vimentin-Controlled Trafficking of Integrin-β1 in Glioblastoma Cells
Published in Brain pathology (Zurich, Switzerland) (01-01-2010)“…Cell motility and resistance to apoptosis characterize glioblastoma (GBM) growth and malignancy. In our current work we report that galectin‐1, a homodimeric…”
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Present and potential future issues in glioblastoma treatment
Published in Expert review of anticancer therapy (01-05-2006)“…The treatment of glioblastomas requires a multidisciplinary approach that takes the presently incurable nature of the disease into consideration. Treatments…”
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13
DNA histogram typing in a series of 707 tumors of the central and peripheral nervous system
Published in The American journal of surgical pathology (01-10-1993)“…The diagnostic value of ploidy level was investigated in a series of 707 tumors (from 707 patients) of the central and peripheral nervous system. The series…”
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Publication practices and standards: recommendations from GSK Vaccines' author survey
Published in Trials (18-11-2014)“…Evolving standards of good publication practice (GPP) and a survey conducted in 2009 of authors, who were investigators and researchers not employed by the…”
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Lectin histochemistry of astrocytic tumors and in vitro characterization of lectin-induced modifications on the proliferation of the SW1088, U373 and U87 human astrocytic cell lines
Published in Journal of neuro-oncology (01-09-1997)“…The role of lectins as biosignalling molecules or as markers of human astrocytic tumors remains relatively unexplored. The aim of the present work is to…”
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Upregulation of galectins‐1 and ‐3 in human colon cancer and their role in regulating cell migration
Published in International journal of cancer (20-01-2003)“…To probe the potential contribution of β‐galactoside‐contributing epitopes and receptor proteins (gal‐1 and gal‐3) to colon malignancy, we first examined the…”
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Galectin-1 Modulates Human Glioblastoma Cell Migration into the Brain Through Modifications to the Actin Cytoskeleton and Levels of Expression of Small GTPases
Published in Journal of neuropathology and experimental neurology (01-07-2002)“…We show that high-grade astrocytic tumors with high levels of galectin-1 expression are associated with dismal prognoses. The immunohistochemical analysis of…”
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Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy
Published in Cancer (01-08-2002)“…BACKGROUND Malignant gliomas of the central nervous system remain associated with dismal prognoses because of their diffuse invasion of the brain parenchyma…”
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Galectin-1 knocking down in human U87 glioblastoma cells alters their gene expression pattern
Published in Biochemical and biophysical research communications (16-09-2005)“…We have previously reported that (i) progression of malignancy in patients bearing astrocytic tumors correlates with increased tumor levels of galectin-1; (ii)…”
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High level of galectin-1 expression is a negative prognostic predictor of recurrence in laryngeal squamous cell carcinomas
Published in International journal of oncology (01-05-2007)“…Monitoring of gene-expression profiles is assumed to refine tumor characterization of laryngeal squamous cell carcinomas (LSCCs) with a therapeutic…”
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