Search Results - "CALDERWOOD, M. A"

Specific oncolytic activity of herpesvirus saimiri in pancreatic cancer cells by STEVENSON, A. J, GILES, M. S, HALL, K. T, GOODWIN, D. J, CALDERWOOD, M. A, MARKHAM, A. F, WHITEHOUSE, A

“…The potential use of oncolytic viruses in the treatment of cancer has been investigated for some time. A variety of agents have been studied, including some…”
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Analysis of Gene Expression in a Human Cell Line Stably Transduced with Herpesvirus Saimiri by Hall, K T, Giles, M S, Goodwin, D J, Calderwood, M A, Carr, I M, Stevenson, A J, Markham, A F, Whitehouse, A

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Proto-genes and de novo gene birth by Carvunis, Anne-Ruxandra, Rolland, Thomas, Wapinski, Ilan, Calderwood, Michael A., Yildirim, Muhammed A., Simonis, Nicolas, Charloteaux, Benoit, Hidalgo, César A., Barbette, Justin, Santhanam, Balaji, Brar, Gloria A., Weissman, Jonathan S., Regev, Aviv, Thierry-Mieg, Nicolas, Cusick, Michael E., Vidal, Marc

“…Novel protein-coding genes can arise either from pre-existing genes or de novo ; here it is shown that functional genes emerge de novo through transitory…”
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ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms by Sheynkman, Gloria M., Tuttle, Katharine S., Laval, Florent, Tseng, Elizabeth, Underwood, Jason G., Yu, Liang, Dong, Da, Smith, Melissa L., Sebra, Robert, Willems, Luc, Hao, Tong, Calderwood, Michael A., Hill, David E., Vidal, Marc

“…Most human protein-coding genes are expressed as multiple isoforms, which greatly expands the functional repertoire of the encoded proteome. While at least one…”
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The carboxy terminus of the herpesvirus saimiri ORF 57 gene contains domains that are required for transactivation and transrepression by Goodwin, Delyth J, Hall, Kersten T, Giles, Mathew S, Calderwood, Michael A, Markham, Alex F, Whitehouse, Adrian

“…Molecular Medicine Unit, University of Leeds, St James’s University Hospital, Leeds LS9 7TF, UK 1 Author for correspondence: Adrian Whitehouse. Fax +44 113 244…”
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Characterization of the herpesvirus saimiri ORF73 gene product by Hall, Kersten T, Giles, Mathew S, Goodwin, Delyth J, Calderwood, Michael A, Markham, Alexander F, Whitehouse, Adrian

“…Molecular Medicine Unit, University of Leeds, St James’s University Hospital, Leeds LS9 7TF, UK 1 Author for correspondence: Adrian Whitehouse. Fax +44 113…”
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Development of herpesvirus-based episomally maintained gene delivery vectors by Calderwood, Michael A, White, Robert E, Whitehouse, Adrian

“…Successful gene therapy aims to deliver and express therapeutic genes to cure or slow the progression of disease. However, a major obstacle in the application…”
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Generation and precise modification of a herpesvirus saimiri bacterial artificial chromosome demonstrates that the terminal repeats are required for both virus production and episomal persistence by White, Robert E, Calderwood, Michael A, Whitehouse, Adrian

“…School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK Correspondence Adrian Whitehouse a.whitehouse{at}leeds.ac.uk Herpesvirus…”
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The herpesvirus saimiri ORF73 gene product interacts with host-cell mitotic chromosomes and self-associates via its C terminus by Calderwood, Michael A, Hall, Kersten T, Matthews, David A, Whitehouse, Adrian

“…1 School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK 2 Institute of Cardiovascular Research, University of Leeds, Leeds LS2…”
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The Herpesvirus Saimiri Open Reading Frame 73 Gene Product Interacts with the Cellular Protein p32 by Hall, Kersten T, Giles, Mathew S, Calderwood, Michael A, Goodwin, Delyth J, Matthews, David A, Whitehouse, Adrian

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Cyclooxygenase inhibitors are potent sensitizers of prostate tumours to hyperthermia and radiation by Asea, A, Mallick, R, Lechpammer, S, Ara, G, Teicher, B A, Fiorentino, S, Stevenson, M A, Calderwood, S K

“…It has previously been demonstrated that hyperthermia can activate prostaglandin synthesis and that prostaglandins are protective against hyperthermia. This…”
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